{"data":[{"id":"10.18131/mex83-1c675","type":"dois","attributes":{"doi":"10.18131/mex83-1c675","identifiers":[],"creators":[{"name":"Xi, Wenna","nameType":"Personal","givenName":"Wenna","familyName":"Xi","affiliation":[{"name":"Northwestern University","affiliationIdentifier":"https://ror.org/000e0be47","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Nunes, Denise A.","nameType":"Personal","givenName":"Denise A.","familyName":"Nunes","affiliation":[{"name":"Northwestern University","affiliationIdentifier":"https://ror.org/000e0be47","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Wang, Xiafei","nameType":"Personal","givenName":"Xiafei","familyName":"Wang","affiliation":[{"name":"University of Kentucky","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Wi, Dahee","nameType":"Personal","givenName":"Dahee","familyName":"Wi","affiliation":[{"name":"University of Illinois Chicago","affiliationIdentifier":"https://ror.org/02mpq6x41","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Li, Xinbo","nameType":"Personal","givenName":"Xinbo","familyName":"Li","affiliation":[{"name":"University of Kentucky","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Schellenberg, Luke","nameType":"Personal","givenName":"Luke","familyName":"Schellenberg","affiliation":[{"name":"Northwestern University","affiliationIdentifier":"https://ror.org/000e0be47","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"title":"Mental health and substance use disorders and care in individuals with sickle cell disease or trait: A scoping review protocol"}],"publisher":"Prism. Galter Health Sciences Library. Northwestern University","container":{},"publicationYear":2026,"subjects":[{"subject":"Anemia, Sickle Cell","subjectScheme":"MeSH"},{"subject":"Sickle Cell Trait","subjectScheme":"MeSH"},{"subject":"Mental Health","subjectScheme":"MeSH"}],"contributors":[],"dates":[{"date":"2026-04-28","dateType":"Issued"},{"date":"2026-04-28","dateType":"Submitted"}],"language":"en","types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Protocol","resourceTypeGeneral":"Text"},"relatedIdentifiers":[{"relationType":"HasVersion","relatedIdentifier":"10.18131/mz4eh-6e719","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"lang":"eng","description":"Background: As a genetic disorder associated with multiple chronic medical comorbidities, individuals with sickle cell disease (SCD) or sickle cell trait (SCT) are reported to have negative mental health outcomes. The different genetic variations of SCD/SCT are associated with various rates and onset of medical comorbidities, which may lead to different rates or severity of comorbid mental health conditions. \n\nObjective: The goal of this scoping review is to elucidate the association between SCD/SCT and mental health conditions, the underlying mechanisms, and existing mental health care management strategies for individuals with SCD/SCT.\n\nMethods: This scoping review follows the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) published in 2018.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"url":"https://prism.northwestern.edu/doi/10.18131/mex83-1c675","contentUrl":null,"metadataVersion":1,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"api","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-04-28T16:40:26Z","registered":"2026-04-28T16:40:26Z","published":null,"updated":"2026-05-22T18:33:12Z"},"relationships":{"client":{"data":{"id":"ghsl.galter","type":"clients"}}}},{"id":"10.18131/mz4eh-6e719","type":"dois","attributes":{"doi":"10.18131/mz4eh-6e719","identifiers":[{"identifier":"oai:prism.northwestern.edu:mz4eh-6e719","identifierType":"oai"}],"creators":[{"name":"Xi, Wenna","nameType":"Personal","givenName":"Wenna","familyName":"Xi","affiliation":[{"name":"Northwestern University","affiliationIdentifier":"https://ror.org/000e0be47","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Nunes, Denise A.","nameType":"Personal","givenName":"Denise A.","familyName":"Nunes","affiliation":[{"name":"Northwestern University","affiliationIdentifier":"https://ror.org/000e0be47","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Wang, Xiafei","nameType":"Personal","givenName":"Xiafei","familyName":"Wang","affiliation":[{"name":"University of Kentucky","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Wi, Dahee","nameType":"Personal","givenName":"Dahee","familyName":"Wi","affiliation":[{"name":"University of Illinois Chicago","affiliationIdentifier":"https://ror.org/02mpq6x41","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Li, Xinbo","nameType":"Personal","givenName":"Xinbo","familyName":"Li","affiliation":[{"name":"University of Kentucky","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]},{"name":"Schellenberg, Luke","nameType":"Personal","givenName":"Luke","familyName":"Schellenberg","affiliation":[{"name":"Northwestern University","affiliationIdentifier":"https://ror.org/000e0be47","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"title":"Mental health and substance use disorders and care in individuals with sickle cell disease or trait: A scoping review protocol"}],"publisher":"Prism. Galter Health Sciences Library. Northwestern University","container":{},"publicationYear":2026,"subjects":[{"subject":"Anemia, Sickle Cell","subjectScheme":"MeSH"},{"subject":"Sickle Cell Trait","subjectScheme":"MeSH"},{"subject":"Mental Health","subjectScheme":"MeSH"}],"contributors":[],"dates":[{"date":"2026-04-28","dateType":"Issued"},{"date":"2026-04-28","dateType":"Submitted"}],"language":"en","types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Protocol","resourceTypeGeneral":"Text"},"relatedIdentifiers":[{"relationType":"IsVersionOf","relatedIdentifier":"10.18131/mex83-1c675","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"lang":"eng","description":"Background: As a genetic disorder associated with multiple chronic medical comorbidities, individuals with sickle cell disease (SCD) or sickle cell trait (SCT) are reported to have negative mental health outcomes. The different genetic variations of SCD/SCT are associated with various rates and onset of medical comorbidities, which may lead to different rates or severity of comorbid mental health conditions. \n\nObjective: The goal of this scoping review is to elucidate the association between SCD/SCT and mental health conditions, the underlying mechanisms, and existing mental health care management strategies for individuals with SCD/SCT.\n\nMethods: This scoping review follows the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) published in 2018.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"url":"https://prism.northwestern.edu/doi/10.18131/mz4eh-6e719","contentUrl":null,"metadataVersion":1,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"api","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-04-28T16:40:26Z","registered":"2026-04-28T16:40:26Z","published":null,"updated":"2026-05-22T18:33:12Z"},"relationships":{"client":{"data":{"id":"ghsl.galter","type":"clients"}}}},{"id":"10.13023/etd.2026.300","type":"dois","attributes":{"doi":"10.13023/etd.2026.300","identifiers":[],"creators":[{"name":"Hyde, Emma E.","nameType":"Personal","givenName":"Emma E.","familyName":"Hyde","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"lang":null,"title":"ENVIRONMENTAL DETECTION AND QUANTIFICATION OF EQUID ALPHAHERPESVIRUSES IN EQUINE FACILITIES USING AIR SAMPLING","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Veterinary sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"4.3"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Equid alphaherpesvirus 1 and 4 (EHV-1/-4) circulate at equestrian facilities, contributing to outbreaks. Due to the complexities of the pathogen, including the limited predictability of reactivation from latency and the effects associated with secondary sites of viral replication, abortion, and neurologic disease, EHV infections are of utmost concern to the equine industry. Recent studies have highlighted the prevalence of the viruses in stabling areas at competitions, though little is known about this phenomenon in other high-traffic equine environments. This thesis presents two studies using air sampling surveillance methods to further explore the viral detection in other equine environments (veterinary facility and racetrack settings) including brief seasonal comparisons in viral shedding and mean genomic copies between experimental infection and field samples collected from facilities with no reported clinical cases. Results showed high frequency of low abundance in viral detection with 26/48 air samples positive for EHV-1 and 24/48 air samples positive for EHV-4 across both studies, suggesting that reactivation from latency and subsequent circulation may be more common than previously thought. Moreover, the substantial difference in the mean genomic copy numbers detected in air between the field study at the racetrack and a controlled EHV-1 infection study (10-fold increase) suggests the difference in airborne detection in the presence of high shedding, clinical cases versus what is detected in environments with no known active cases. Together, these studies will advance our knowledge of the disease, emphasizing the importance of early detection of the virus and the role of surveillance in mitigating the impact of EHV-1 and EHV-4 on the equine industry.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Emma E. Hyde","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"International Equestrian Federation","awardNumber":"2023-01180922","funderIdentifier":null,"funderIdentifierType":"Other"},{"awardUri":null,"awardTitle":"Summer Research Grant","funderName":"Lincoln Memorial University","awardNumber":null,"funderIdentifier":"https://doi.org/10.13039/100019232","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/gluck_etds/78/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-21T14:07:45Z","registered":"2026-05-21T14:07:46Z","published":null,"updated":"2026-05-21T14:07:46Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.249","type":"dois","attributes":{"doi":"10.13023/etd.2026.249","identifiers":[],"creators":[{"name":"Li, Kai","nameType":"Personal","givenName":"Kai","familyName":"Li","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0005-4426-0837","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"Technical Progression in Mammalian Genome Assembly","titleType":null},{"lang":null,"title":"From Reference Refinement to Haplotype-Resolved Telomere-to-Telomere Reconstruction","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Veterinary sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"4.3"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Long read sequencing and modern assembly algorithms have substantially advanced mammalian genome reconstruction yet repeat rich regions and complex structural variation remain difficult to resolve. This dissertation documents a progression in genome assembly strategies from reference refinement to haplotype-resolved and telomere-to-telomere (T2T) reconstruction. I first contributed to the development of the rat reference assembly GRCr8, integrating PacBio HiFi sequencing, Bionano optical mapping, and targeted curation. The resulting 2.85 Gb assembly achieved 98.7% chromosomal assignment, a scaffold N50 of 137 Mb, and a Merqury QV of 59.5. Next, haplotype-resolved T2T assemblies were generated for horse and donkey derived from a mule using trio-binning and long-read sequencing, improving BUSCO completeness and achieving phased chromosome-scale assemblies with a Merqury score of 52.5. Finally, integration of PacBio HiFi, ultra-long Oxford Nanopore reads, and Hi-C scaffolding enabled T2T reconstruction of the rat genome (SHRSP), achieving an overall QV of 65.0 and 15 of 22 chromosomes assembled gaplessly. Multiple high-quality rat assemblies further supported construction of a graph-based pangenome and systematic analysis of strain-specific structural variation. Together, these studies demonstrate stepwise gains in genome continuity, accuracy, and structural resolution enabled by long-read and haplotype-aware assembly strategies.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Kai Li","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":"Grant","funderName":"National Institutes of Health","awardNumber":"1R01 HG011252-01A1","funderIdentifier":"https://doi.org/10.13039/100000002","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/gluck_etds/77/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T16:34:20Z","registered":"2026-05-20T16:34:20Z","published":null,"updated":"2026-05-20T16:34:20Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.247b","type":"dois","attributes":{"doi":"10.13023/etd.2026.247b","identifiers":[],"creators":[{"name":"Ochoa, Rebeca Ponce","nameType":"Personal","givenName":"Rebeca Ponce","familyName":"Ochoa","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"lang":null,"title":"UNA LIMA MULTICULTURAL","titleType":null},{"lang":null,"title":"LA CULTURA MATERIAL DE LAS MUJERES AFROPERUANAS DURANTE LOS SIGLOS XVI Y XVII","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: History and archaeology","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"6.1"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Uno de los valores más importantes de una sociedad es la cultura adquirida a través del conocimiento, de la tradición y de la historia donde el intercambio de experiencias en la ciudad limeña hizo posible la construcción de una cultura material. Los documentos producidos, adaptados y aceptados a un determinado contexto social refuerzan la identidad, la cultura y la memoria de una colectividad.\n\nPor ello, esta investigación tiene como objetivo analizar los autos de fe y los testamentos de mujeres afroperuanas en los siglos XVI y XVII como parte del material cultural que ayudan a pensar y reconstruir el pasado. La vestimenta, la posesión de esclavos, de bienes o las reliquias religiosas modelaron una nueva identidad afroperuana que modificó las dinámicas de poder, de género y raza. El objetivo es rescatar lo material en lo textual para examinar la vida de estas mujeres, cómo adaptaron los cambios culturales a sus propias creencias y cómo a través de su cuerpo y voz reclamaron su estatus en el Perú colonial.\n\nPor tanto, la cultura material se conforma de los elementos que ayudaron a estas mujeres a crear una nueva identidad y agencia femenina en la sociedad colonial rompiendo la idea de subordinación y abriendo un espacio de libertad que les permitió avanzar social y económicamente. De esta forma, las mujeres afroperuanas modificaron los elementos culturales introducidos por la sociedad colonial, adaptándolos de acuerdo con sus creencias y necesidades lo que resultó en una transformación sociocultural que aporta una nueva perspectiva dentro de los estudios coloniales.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Rebeca Ponce Ochoa","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/hisp_etds/72/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T16:31:36Z","registered":"2026-05-20T16:31:37Z","published":null,"updated":"2026-05-20T16:31:37Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.05","type":"dois","attributes":{"doi":"10.13023/etd.2026.05","identifiers":[],"creators":[{"name":"Melissa Peters","nameType":"Personal","givenName":"Melissa Peters","familyName":null,"affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0008-2082-947X","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"BURNOUT AND MINDFUL SELF-CARE PRACTICES AMONG BIPOC WOMEN MUSIC THERAPISTS","titleType":null},{"lang":null,"title":"A CROSS-SECTIONAL SURVEY","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Psychology","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.1"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Music therapy as a profession has long acknowledged burnout as a significant occupational concern, yet the experiences of marginalized therapists remain understudied. In particular, little research has explored how burnout and self-care manifest for those who identify as Black, Indigenous, or People of Color (BIPOC) women in a field historically dominated by white women. Most of the existing literature on this topic is focused on the majority identity of music therapists, white women. The purpose of this thesis was to examine the reported levels of burnout among BIPOC women music therapists as well as their reported frequency of engagement in self-care strategies and the relationships between the two. I sent a survey to the certification board of music therapy email list. The survey was composed of the Maslach Burnout Inventory-Human Services Survey and the Brief-Mindful Self-Care Scale (B-MSCS). The survey was completed by 59 participants, all of whom identified as BIPOC women therapists, from various racial/ethnic identities, work settings, and regions. The results indicated moderate to high levels of burnout. Participants reported engaging most frequently in the self-care domain of supportive relationships, with moderate engagement in the self-care domains of supportive structure, self-compassion and purpose. The lowest engagement was seen in the self-care domains of mindful relaxation, physical care, and mindful awareness. Burnout and depersonalization both showed a negative correlation with mindful relaxation practices, self-compassion, purpose, supportive relationships, supportive structure, and mindful awareness but showed a positive correlation to physical care. Burnout showed a statistically significant negative correlation with mindful awareness. Depersonalization showed a statistically significant negative correlation with supportive structure and mindful awareness. Personal achievement showed a positive correlation with all dimensions of the B-MSCS but had a statistically significant positive correlation with self-compassion and purpose, supportive relationships, supportive structure, and mindful awareness. Personal achievement showed the most statistically significant correlations with the dimensions of the B-MSCS while Burnout showed the least. This study is important because it fills some of the gaps in the literature when discussing burnout among music therapists and how differences in gender and racial/ethnic identity can influence the overall effectiveness of self-care strategies to combat burnout.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Melissa V. Peters","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"UNITE Research Priority Area","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"},{"awardUri":null,"awardTitle":null,"funderName":"University of Kentucky School of Music","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"}],"url":"https://uknowledge.uky.edu/music_etds/301/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T16:16:07Z","registered":"2026-05-20T16:16:08Z","published":null,"updated":"2026-05-20T16:16:08Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.03","type":"dois","attributes":{"doi":"10.13023/etd.2026.03","identifiers":[],"creators":[{"name":"Kane, Caroline","nameType":"Personal","givenName":"Caroline","familyName":"Kane","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0009-4055-9427","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"THE ROLE OF NUTRITION IN MANAGING HONEY BEE VIRAL PATHOGEN","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2025,"subjects":[{"subject":"FOS: Biological sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"1.6"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"This study evaluated the impact of nutritional supplements on viral infections in honey bee colonies, focusing on Lake Sinai Virus 2 (LSV2), Deformed Wing Virus A (DWVA), and Deformed Wing Virus B (DWVB). I partnered with 32 hobbyist beekeepers across Kentucky, who volunteered 138 colonies for a month-long field study. Half of the colonies received weekly commercial supplements, while the other half served as controls. Viral titers were measured before and after the supplementation period using qPCR. Supplements did not significantly reduce viral titers for any of the three viruses, suggesting that short-term supplementation may not be effective in lowering infection levels. However, variation between months and among beekeepers with different management practices underscores the importance of accounting for seasonal and individual management factors. This report offers a starting point for understanding how hobbyist beekeeper colony management practices intersect with viral dynamics and highlights the need for longer-term studies to inform practical disease management strategies.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Caroline Wylie Kane","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"Kentucky Agricultural Development Fund","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"},{"awardUri":null,"awardTitle":null,"funderName":"National Science Foundation","awardNumber":null,"funderIdentifier":"https://doi.org/10.13039/100000001","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/entomology_etds/101/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T15:53:35Z","registered":"2026-05-20T15:53:35Z","published":null,"updated":"2026-05-20T15:53:35Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.250b","type":"dois","attributes":{"doi":"10.13023/etd.2026.250b","identifiers":[],"creators":[{"name":"Eertink, Lianne","nameType":"Personal","givenName":"Lianne","familyName":"Eertink","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0000-2255-6366","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"EQUINE ROTAVIRUS A","titleType":null},{"lang":null,"title":"INVESTIGATION INTO IMMUNE RESPONSES TO VACCINATION, AND GENETIC DIVERSITY AND THEIR IMPLICATIONS FOR ROTAVIRUS A OUTBREAKS IN HORSES WITHIN THE UNITED STATES OF AMERICA","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Veterinary sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"4.3"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Despite a monovalent G3P[12] (‘G3’) vaccine being available for horses, equine rotavirus A (ERVA) is still the predominant infectious pathogen causing diarrhea in foals in the United States of America (U.S.). ERVA is classified into G genotypes based on the VP7 protein and P genotypes based on the VP4 protein. Two genotypes of ERVA, G3 and G14P[12] (‘G14’) are currently circulating in U.S. horses. Mares are immunized at 8, 9, and 10 months of gestation with the G3 vaccine and maternal antibodies are passively transferred to foals through colostrum. Outbreaks in foals from unvaccinated mares can be observed as early as 12 hours of age, while outbreaks in foals from vaccinated mares predominantly occur at later ages.\n\nThe first aim of our study was to determine how long virus neutralizing maternal antibodies from ERVA vaccinated dams persist in foals. For this aim, clinical samples including serum, milk, colostrum, and fecal swab samples were collected from 50 mare-foal pairs. Serum, colostrum, and milk samples were quantitatively tested for protective antibodies using a cell-based virus neutralization assay for both G3 and G14 viruses, while fecal swabs were analyzed by RT-qPCR for detection of ERVA genome. The absence of virus neutralizing antibodies (NAbs) in foal pre-nursing samples and the presence thereof after nursing confirmed that these NAbs are transferred through the colostrum. We also found that there is variation in the ratio of NAbs transferred between mares and their foals. Furthermore, results of our studies demonstrated a substantial cross-reactivity between G3 and G14 viruses in horses in that NAb titers against the G14 virus are approximately 2-4-fold lower than those against the homologous G3 virus. Both G3 and G14 NAb titers decreased steadily over time in foals with the lowest titers measured at approximately 4 months of age which is in line with when ERVA infections are observed in foals from vaccinated dams.\n\nThe second aim of our work was to determine if it is possible to increase NAb titers in foals through vaccination before they are vulnerable to ERVA infection. We immunized two foals with the commercially available vaccine (G3) at solely three months of age, seven foals at both two and three months of age, and two mock foals were vaccinated with saline buffer. The dams of these foals were not vaccinated during their gestation period. All pre-vaccination G3 and G14 NAb titers in this foal cohort were 256 or lower. Following vaccination, NAb titers in foals were increased up to 1024 against G3 and 512 against G14 viruses, respectively. Interestingly, NAb titers were stabilized in immunized foals, which contrasts with unvaccinated foals showing a rapid decline in NAb titers over time.\n\nIn the third aim of this project, we proposed to characterize the genetic diversity of current circulating genotypes in U.S. horses and determine whether the identified viruses behave different from each other in in vitro replication and antigenic property. A multidisciplinary approach including virus isolation, sequencing, genetic analysis, and antigenic characterization was utilized. Among 160 ERVA positive samples collected from 22 states, genotype-specific RT-PCR analysis showed 96 samples were positive for solely G3, 11 samples for G14, 52 samples for both G3 and G14, and 1 uncharacterized ERVA was identified. Thirty-three positive samples were sequenced using Illumina© MiSeq platform. Based on whole genome analysis, twenty unique viruses were identified. Based on amino acid sequences thirteen viruses were unique in genomic segment 4 (VP4) and 7 in segment 9 (VP7). Furthermore, extensive reassortment was detected among these viruses, indicating that co-infection of homologous and heterologous genotypes (G3 and G14) is common in horses, leading to the generation of new strains. Genetically different viruses were antigenically characterized using rabbit and equine sera. Despite no major antigenic differences observed between strains within the same genotype, rabbit serum, but not equine serum, distinguished the antigenic drift between G3 and G14 genotypes. Finally, experiments showed a genotype-dependent difference in replication kinetics with G14 viruses appearing to replicate slower than G3 viruses. This work revealed a novel host species-specific immunity against ERVA, which will be important for future rotavirus vaccine research.\n\nOverall, these studies show that ERVA maternal antibodies decrease over time in foals which is in line with when most infections in foals from vaccinated dams are observed in the field study. NAbs generated in response to the G3 vaccine were cross-protective against G14, indicating that the current vaccine may sufficiently protect horses from both genotypes. Furthermore, it was shown that vaccination of foals is possible, however, the timepoint of vaccination and the pre-vaccination ERVA NAb titer is of influence on the immune response to vaccine antigens. Lastly, no isolates were identified that are antigenically different from each other within the G3 and within the G14 genotypes. However, viruses with different replication fitness were identified, indicating the potential emergence of evolutionary advanced rotaviruses with altered transmissibility in horses.\n\nDespite the research presented in this dissertation that can offer novel insights to infection landscape of ERVA and vaccine-mediated protection in U.S. horses, challenge experiments involving vaccinated horses will shed light on the exact ERVA NAb titers needed to protect foals from infection and clinical disease. Furthermore, continued surveillance and isolation of future field strains from severely ill or diseased foals are important for the rapid identification of antigenically drifted strains so proper control and vaccination strategies can be implemented to protect foal health and mitigate economic losses to the equine industry. The development of a reverse genetic system would be useful for elucidating the impact of genetic mutations on viral antigenic property and determining the correlations of antibody-mediated protection.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Lianne G. Eertink","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":"Maxwell and Muriel Gluck Fellowship","funderName":"University of Kentucky Department of Veterinary Science","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"},{"awardUri":null,"awardTitle":null,"funderName":"William Robert Mills Endowed Chair Fund","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"},{"awardUri":null,"awardTitle":null,"funderName":"Zoetis","awardNumber":null,"funderIdentifier":"https://doi.org/10.13039/100012895","funderIdentifierType":"Crossref Funder ID"},{"awardUri":null,"awardTitle":null,"funderName":"National Institute of Food and Agriculture","awardNumber":"2025-67016-44998","funderIdentifier":"https://doi.org/10.13039/100005825","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/gluck_etds/76/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T15:44:55Z","registered":"2026-05-20T15:44:56Z","published":null,"updated":"2026-05-20T15:44:56Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.245","type":"dois","attributes":{"doi":"10.13023/etd.2026.245","identifiers":[],"creators":[{"name":"Todd-Voyten, Jeffrey","nameType":"Personal","givenName":"Jeffrey","familyName":"Todd-Voyten","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0003-0775-0066","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"Implementations of Improvisation and Existing Materials in Electroacoustic Composition","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Arts (arts, history of arts, performing arts, music)","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"6.4"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"I have developed my compositional process through the use of sound synthesis, existing materials, and improvisation. When combining these techniques and resources, human gestures can emerge from inhuman materials in a dialogue between machines and humans. This thesis is an overview of my initial inquiries into the continuum of human agency and machine intervention, considering aspects of patch-programming, formal structure, and performance practice. In addition to the aforementioned compositional methods, this thesis also considers musico-dramatic meaning and personal musical influences outside the scope of electroacoustic music.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Jeffrey Todd-Voyten","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/music_etds/300/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T15:35:32Z","registered":"2026-05-20T15:35:32Z","published":null,"updated":"2026-05-20T15:35:32Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.246b","type":"dois","attributes":{"doi":"10.13023/etd.2026.246b","identifiers":[],"creators":[{"name":"Thiranya Abeyrathne, Dilni","nameType":"Personal","givenName":"Dilni","familyName":"Thiranya Abeyrathne","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0001-5477-6889","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"MUSINGS OF THE HOME GARDEN","titleType":null},{"lang":null,"title":"CONTRIBUTIONS OF SMALL-SCALE AGRICULTURE TO INFORMAL ECONOMIES AND RELATIONAL ECOLOGIES IN SELECT RURAL AND SEMI-RURAL VILLAGES IN KANDY, SRI LANKA","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Social and economic geography","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.7"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Sri Lanka’s 2020 economic crisis has led to concerns regarding the state’s capacity to support localities through precarity in relation to food production and everyday living. This study examines this aspect of crisis through an exploration of home gardens in Kandy, Sri Lanka and their capacity to mitigate and maneuver around moments of crisis and precarity through the development of cultivations, sociocultural relations, and melded diverse economic forms. In Kandy, home gardens are a long-held historical small-scale agriculture practice that evolved out of Kandyan forest gardens, an agroforestry practice that combined maintenance of a forest landscape with intentional and interspersed cultivation of produce, including vegetables, fruits, spices, trees, and ornamental species. Drawing on diverse economic frameworks and studies on everyday precarity, I demonstrate how home gardens function as a multi-use system of subsistence agriculture that weaves together gift economies of gift-as-exchange, communal cultivations on privatized lands (based in the locality), responses to precarity through agentic food production in the home garden, and the paradox of precarity through home garden continuity and state support.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Dilni T. Abeyrathne","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":"Barnhart-Withington Block fund, Food Connection grant","funderName":"University of Kentucky","awardNumber":null,"funderIdentifier":"https://doi.org/10.13039/100007472","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/geography_etds/118/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T15:29:16Z","registered":"2026-05-20T15:29:17Z","published":null,"updated":"2026-05-20T15:29:17Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.188","type":"dois","attributes":{"doi":"10.13023/etd.2026.188","identifiers":[],"creators":[{"name":"Bryant, George C.","nameType":"Personal","givenName":"George C.","familyName":"Bryant","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0005-1625-4894","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"USING CONTROLLED INTERRUPTEDTIME SERIES TO QUANTIFY COVID-19 PANDEMIC-ASSOCIATED CHANGES IN CLABSI RATES IN ONCOLOGY INPATIENT LOCATIONS","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Other medical sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"3.5"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Background: Prior to the COVID-19 Pandemic, central line-associated bloodstream infection (CLABSI) rates in the United States (U.S.) were on a sustained downward trajectory. The pandemic abruptly reversed this progress, with national CLABSI rates increasing approximately 24% between 2019 and 2020. Oncology inpatient locations carry disproportionately high baseline CLABSI rates, driven largely by mucosal barrier injury laboratory-confirmed bloodstream infections (MBI-LCBI), yet no studies have directly examined how the pandemic differentially affected CLABSI rates in oncology versus non-oncology inpatient settings.\n\nObjective: To assess whether the onset of the COVID-19 pandemic was associated with differential changes in LCBI-only and MBI-LCBI rates in oncology inpatient locations compared to non-oncology inpatient locations within the same U.S. hospitals.\n\nMethods: A retrospective controlled interrupted time series analysis was conducted using NHSN inpatient location-level data from January 2018 through December 2024. The interruption was defined as March 2020. The primary cohort included 3,686 locations across 339 hospitals. Outcomes were analyzed separately for LCBI-only and MBI-LCBI-only. Negative binomial generalized linear mixed models estimated immediate level changes, post-interruption slope changes, and differential effects for oncology versus non-oncology locations, with non-oncology locations within the same hospital serving as the comparison group.\n\nResults: Contrary to our hypothesis, oncology locations experienced a smaller immediate pandemic-associated increase in LCBI-only rates than non-oncology locations (differential IRR 0.740, 95% CI 0.678–0.807), converging to near-equivalence by 48 months (IRR 0.978, 95% CI 0.886–1.079). No statistically significant differential effect was identified for MBI-LCBI. Observed rates in both location types remained substantially above no-interruption counterfactual predictions through December 2024, with oncology LCBI-only and MBI-LCBI rates exceeding predicted levels by 96% and 36%, respectively.\n\nConclusion: The COVID-19 pandemic produced sustained CLABSI increases that had not returned to pre-pandemic trajectories by December 2024, and those increases did not affect oncology locations as hypothesized. These findings underscore that LCBI-only and MBI-LCBI are distinct outcomes requiring distinct prevention strategies.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 George C. Bryant","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/epb_etds/51/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T15:22:23Z","registered":"2026-05-20T15:22:23Z","published":null,"updated":"2026-05-20T15:22:23Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.235","type":"dois","attributes":{"doi":"10.13023/etd.2026.235","identifiers":[],"creators":[{"name":"Alsum, Alexia","nameType":"Personal","givenName":"Alexia","familyName":"Alsum","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0008-5659-9493","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"DESIGN AND ADVANCEMENT OF ANALYTICAL FRAMEWORKS FOR IN VIVO SINGLE-PHOTON CALCIUM IMAGING TO CHARACTERIZE TEMPORAL- AND TREATMENT-DEPENDENT NEURAL ADAPTATIONS TO OPIOID EXPOSURE AND WITHDRAWAL IN THE MEDIAL PREFRONTAL CORTEX","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Other medical sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"3.5"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Despite the availability of several approved medications for opioid use disorder (OUD), it remains a significant public health concern characterized by persistent neurobiological adaptations that drive relapse and impede successful recovery. The medial prefrontal cortex (mPFC), a region critical for executive control and decision-making, undergoes pronounced functional changes during chronic opioid exposure and withdrawal, yet the cellular mechanisms underlying these adaptations remain poorly understood. This dissertation aims to investigate longitudinal alterations in mPFC neural activity across opioid exposure and withdrawal using in vivo single-photon calcium imaging and newly developed computational frameworks.\n\nFollowing standard preprocessing to extract and normalize calcium traces, custom computational pipelines were developed to analyze longitudinal patterns of neuronal activity across recording sessions. These frameworks incorporated dimensionality reduction and clustering approaches to identify neuronal ensemble activity patterns that evolved across time and treatment conditions. The developed tools were applied to calcium imaging datasets from two complementary experiments: (1) chronic oxycodone administration via osmotic minipump followed by a short withdrawal period and (2) twice-daily injections of oxycodone or atoxifent, a novel μ-opioid receptor agonist, followed by extended withdrawal.\n\nAcross both models, longitudinal analysis revealed distinct neuronal populations that either maintained stable activity profiles or exhibited dynamic, treatment-dependent changes during exposure and withdrawal. These findings suggest that chronic opioid administration induces circuit-level remodeling within the mPFC, characterized by shifting ensemble activity states that likely contribute to impaired behavioral regulation observed in OUD. Significant baseline sex differences in neural activity were also detected, whereas limited sample sizes in post-treatment recordings precluded robust evaluation of sex-dependent effects following drug exposure.\n\nCollectively, this work advances analytical approaches for longitudinal calcium imaging and demonstrates their value in revealing temporal and treatment-dependent neurophysiological changes during opioid exposure and withdrawal. By enabling quantitative assessment of circuit-level adaptations over time, these frameworks provide a foundation for evaluating how candidate compounds influence neuronal ensemble activity within addiction-relevant networks. This approach supports preclinical drug screening and the identification of novel therapeutic targets aimed at restoring prefrontal function disrupted by chronic opioid use. More broadly, the analytical strategies developed here expand the utility of in vivo calcium imaging and strengthen the link between mechanistic neurobiology and translational pharmacotherapy development.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Alexia R. Alsum","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/pharmacy_etds/177/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-20T15:16:01Z","registered":"2026-05-20T15:16:01Z","published":null,"updated":"2026-05-20T15:16:01Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.103","type":"dois","attributes":{"doi":"10.13023/etd.2026.103","identifiers":[],"creators":[{"name":"Al-kayed, Jarrah","nameType":"Personal","givenName":"Jarrah","familyName":"Al-kayed","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0003-4650-8080","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"WORKPLACE VIOLENCE, RISKY ALCOHOL USE, AND PHYSICAL ACTIVITY AMONG NURSES","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Psychology","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.1"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"The high prevalence of workplace violence places nurses at risk of poor well-being. Some nurses use alcohol to cope with workplace violence. Alcohol use however, is associated with increased physical, psychosocial, and occupational problems, which exacerbate nurses’ well-being. Studies have shown that 13% to 37% of nurses have risky alcohol use behaviors. Given that physical activity correlates with reduced risky alcohol use, the purpose of this dissertation was to: 1) synthesize the literature regarding the association of work- and trauma-related factors and risky alcohol use among healthcare providers; 2) evaluate the psychometric properties of the Brief Young Adult Alcohol Consequences Questionnaire (BYAACQ) among nursing students; and 3) examine the moderating effect of physical activity on the association of workplace violence with risky alcohol use among nurses. The findings of this dissertation indicated that trauma was significantly associated with risky alcohol use among healthcare providers, the BYAACQ demonstrated adequate psychometric properties in nursing students, and the significant relationship between workplace violence and risky alcohol use wasnot seem moderated by physical activity. In the future, researchers should consider longitudinal designs or randomized controlled intervention trials to address workplace violence, risky alcohol use, and physical activity among nurses.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Jarrah Al-Kayed","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"Delta Psi Chapter Theta Tau Awards and Scholarship","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"}],"url":"https://uknowledge.uky.edu/nursing_etds/78/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:39:27Z","registered":"2026-05-19T16:39:28Z","published":null,"updated":"2026-05-19T16:39:28Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.31","type":"dois","attributes":{"doi":"10.13023/etd.2026.31","identifiers":[],"creators":[{"name":"Loosle, Allison N.","nameType":"Personal","givenName":"Allison N.","familyName":"Loosle","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"lang":null,"title":"The Association Between Learned Helplessness and Future Outlook and the Mediating Effects of Parental Support, Engagement, and Closeness","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Psychology","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.1"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"The present study examined the direct and indirect associations between learned helplessness and future outlook among emerging adults, with parental support, engagement, and closeness as potential mediating factors. Using data from 375 participants drawn from G3, Wave 4 of the Youth Development Study, two path analytic models were tested: one including a composite measure of learned helplessness and one examining its components (contingency, cognition, and behavior) individually. Results indicated that higher levels of learned helplessness were associated with a less positive future outlook. When separated, the cognition and behavior components were negatively associated with future outlook, whereas contingency was not associated. Among parental factors, male parent closeness was the only variable consistently associated with future outlook and partially mediated the association between composite learned helplessness and future outlook. Findings highlight the importance of cognitive self-evaluations and the father–child subsystem within a family systems framework. Implications for understanding developmental processes during emerging adulthood and for clinical interventions targeting cognitive appraisals and relational dynamics are discussed.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Allison N. Loosle","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/hes_etds/128/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:35:17Z","registered":"2026-05-19T16:35:17Z","published":null,"updated":"2026-05-19T16:35:17Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.29","type":"dois","attributes":{"doi":"10.13023/etd.2026.29","identifiers":[],"creators":[{"name":"Goh, Jensen","nameType":"Personal","givenName":"Jensen","familyName":"Goh","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-8879-7864","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"EXPANDING THE ROLE OF MUSCLE STEM CELL FUSION IN MUSCLE UNDER HYPERTROPHIC STIMULUS","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Biological sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"1.6"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Muscle stem cells (MuSCs) are a unique stem cell population that can activate in response to both injury and growth stimuli. Studies on muscle regeneration have shown MuSC activation follows a uniform progression through proliferation, differentiation, and fusion. Therefore, to determine whether MuSC replication is a prerequisite for differentiation under hypertrophic stimulus, I used a lineage-tracking mouse model (Pax7rtTA; TRE-H2B-GFP) to label MuSC nuclei and simultaneously tracked DNA synthesis via EdU incorporation. This dual-labeling approach allowed us to not only distinguish MuSC-derived nuclei but also demarcate which MuSC had proliferated prior to fusion. I then employed a mechanical overload (MOV) model of synergist ablation on the hindlimb muscles; this model has been shown to stimulate robust activation and fusion of the MuSC population in the plantaris muscle.\n\nUsing immunohistochemistry, I quantified GFP+ MuSC-derived myonuclei within myofibers in concert with the EdU labeling. My analysis showed that a significant fraction of GFP+ MuSC-derived myonuclei were negative for EdU. This unexpected finding showed that, in response to hypertrophic stimulus, cell division is not obligatory for MuSC fusion during muscle growth. Further, trajectory analysis of our scRNA-seq data revealed a bifurcation in MuSC fate: one branch progressed to a proliferative state prior to fusion, whereas the other routed directly to differentiation and fusion without proliferation. Together, these findings provide strong evidence that the MuSC dynamics are different with hypertrophy compared to previous studies in the muscle damage and regeneration context, and that MuSC are capable of fusion into the muscle fibers independent of proliferation.\n\nNext, I wanted to examine the fate of MuSC organelles other than the nucleus when fusion occurs. Previously, tracking the fusion of MuSC to myofibers during muscle hypertrophy has been exclusively done by assessing myonuclear abundance. These nuclear-centric methods have directed the focus of study on myonuclear accretion. As it stands in the field, the increase in transcriptional capacity is thought to be the primary functional benefit of MuSC fusion. However, little is known about the fate of other organelles such as mitochondria, ribosomes, and lysosomes during myofiber fusion. While it is presumed that these organelles are also transferred and retained within muscle fibers post-fusion, there is no direct evidence to support this presumption.\n\nTo address this gap in knowledge, I focused on mitochondria because they are a highly abundant organelle in activated MuSCs. Alongside, there is a well-established mitochondrial marker, mito-Dendra2, which will allow us to track the fate of MuSC-derived mitochondria following myofiber fusion.  I crossed a MuSC-specific driver mouse to the fluorescent reporter mouse to generate a MuSC-specific mitochondrial labeled mouse. I then subjected the mice to the same (MOV) model to stimulate MuSC fusion. Plantaris muscles were collected after 3-, 7-, and 14- days of MOV. This experimental design allowed us to evaluate whether mitochondrial transfer precedes fusion and to assess MuSC temporal dynamics. I observed an increase in Dendra2⁺ myofibers across the MOV time course. Super-resolution imaging captured the simultaneous transfer of mitochondria and nuclei during MuSC fusion, visualizing direct evidence of mitochondrial transfer into muscle fibers in response to a hypertrophic stimulus. EdU incorporation, to track MuSC fusion, showed early MuSC fusion was primarily independent of proliferation and preferentially occurred with oxidative Type 2A fibers.\n\nThus, with this study, I provide for the first time definitive evidence that under a hypertrophic stimulus, mitochondria are transferred into muscle fibers through MuSC fusion. Furthermore, the sensitivity of our model allowed us to characterize the dynamics of early MuSC fusion; I show that MuSCs are fusing earlier than 3 days and that this fusion is largely preferential to 2A fibers in the plantaris.\n\nIn my final study, I investigated the transcriptomic impact of MuSC fusion on muscle in the context of two key variables: adaptation to a hypertrophic stimulus and the effects of aging. Our lab previously showed that at least in the short term, adult muscle is able to grow at a similar level in the absence or presence of MuSCs; but on the opposite end, growth response of aged muscle is blunted irrespective of MuSC presence. Therefore, I wanted to perform sequencing on muscle under these conditions. Because the size of the myofiber (muscle cell) prohibits us from using single cell isolation, I instead opted to focus on the myonucleus for sequencing. To achieve this, I used a mouse model in which MuSCs could be selectively depleted and allow us to simultaneously label myonuclei. I also utilized the same synergist ablation model to induce a hypertrophic stimulus via MOV on the adult and aged mice of this mouse model.\n\nThis allowed me to compare the transcriptome of murine muscle in the presence or absence of MuSCs, in resting or (MOV) models, and both in adult and aged conditions; thereby isolating the transcriptional consequences of MuSC-derived fusion across age and MOV adaptation. After integrating all datasets, my comparisons revealed four significant findings: 1) Adult muscle can adapt to mechanical overload in the absence of MuSCs,2) MOV adaptation was blunted in aged muscle, and the blunting is amplified with MuSC depletion,3) Aging muscle has many additional myonuclear clusters that exhibit non-canonical expression of genes, 4) MOV rejuvenates aged muscle transcriptome, but only in the presence of MuSCs.\n\nOverall, I showed that MuSCs play a much bigger role in regulating adaptation in aged muscle, while adult muscle can compensate without MuSCs. Based on the additional myonuclear clusters in aged samples, our data suggests that with aging, transcriptional dysregulation occurs. Finally, while previous studies have shown the benefits of exercise in attenuating aging effects, this study provides the first detailed characterization of how MOV remodels aged muscle transcriptome and highlight the MuSC contribution to this response.\n\nOverall, my work has extended our understanding of MuSC fusion by demonstrating that MuSCs can contribute to myofiber growth through a proliferation-independent route. Beyond nuclear accretion, my findings establish for the first time that MuSCs also donate mitochondria during fusion and a preference for early MuSC fusion with oxidative Type 2A fibers. I show that adult muscle retains the ability to compensate for MuSC loss during hypertrophy and that this adaptive capacity is diminished with aging due to a loss in myonuclear transcriptional programs. Although the single nuclear RNA sequencing project is descriptive and based solely on bioinformatic data at a transcriptional level, the results provide evidence that MOV-specific rejuvenation of muscle occurs through the reprogramming of aged myonuclei. This suggests that resistance exercise in the presence of MuSCs might restore aged muscle to a more youthful profile.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Jensen Goh Zhong Sheng","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"National Institutes of Health","awardNumber":"RO1 AG069909","funderIdentifier":"https://doi.org/10.13039/100000002","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/physiology_etds/74/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:32:29Z","registered":"2026-05-19T16:32:29Z","published":null,"updated":"2026-05-19T16:32:29Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.90","type":"dois","attributes":{"doi":"10.13023/etd.2026.90","identifiers":[],"creators":[{"name":"Tahsin, Samiha","nameType":"Personal","givenName":"Samiha","familyName":"Tahsin","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0002-9449-2271","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"IONIC-ELECTRONIC INTERACTIONS GOVERNING CHARGE TRANSPORT AND PERFORMANCE IN ORGANIC ELECTROCHEMICAL TRANSISTORS","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Electrical engineering, electronic engineering, information engineering","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"2.2"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Organic electrochemical transistors (OECTs) use organic mixed ionic electronic conductors (OMIECs) as the active material because of their unique ability to transport both electronic and ionic charge carriers and operate in an aqueous environment. Moreover, OECTs provide a wide range of applications, starting from biosensors, energy storage, and neuromorphic computing. In spite of the significant prospect of OECTs, there is a critical gap in understanding the fundamental properties during device operation, including charge transport, charge injection mechanism, contact geometry, and electrolyte solvent properties.\n\nIn this study, low-temperature measurement of OECT device parameters such as mobility, contact resistance, and activation energy challenges the existing assumption of charge transport physics in heavily doped OMIECs. Mobility-temperature trend indicates multiple trap and release as the dominant charge transport mechanism, while contact resistance-temperature trend indicates tunneling as the dominant charge injection mechanism. Next, conductance-temperature data show a reversible insulator-to-metal transition at high carrier densities, which is observed here for the first time in OMIECs and OECTs. Furthermore, a deviation from the gradual channel approximation model is observed due to the presence of edge effects at narrower channels and voltage-dependent channel resistance.\n\nOverall, this work provides a combined framework that shows how the OECT performance is influenced by the complex interplay of electronic-ionic interactions, carrier density, device geometry, and electrolyte solvent. This analysis paves a clear path for future design of high-performance OECT devices with proper estimation of device parameters and a deeper understanding of device physics.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Samiha Tahsin","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":"Faculty Early Career Development Award","funderName":"National Science Foundation","awardNumber":"2441261","funderIdentifier":"https://doi.org/10.13039/100000001","funderIdentifierType":"Crossref Funder ID"},{"awardUri":null,"awardTitle":"Mathematical and Physical Sciences Program","funderName":"National Science Foundation","awardNumber":"2349830","funderIdentifier":"https://doi.org/10.13039/100000001","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/ece_etds/230/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:28:35Z","registered":"2026-05-19T16:28:35Z","published":null,"updated":"2026-05-19T16:28:35Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/des.2026.515","type":"dois","attributes":{"doi":"10.13023/des.2026.515","identifiers":[],"creators":[{"name":"Carroll, Jennifer","nameType":"Personal","givenName":"Jennifer","familyName":"Carroll","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"lang":null,"title":"Assessing Legacy Collections","titleType":null},{"lang":null,"title":"Analyzing the Preservation, Recovery, and Interpretive Value of Archaeobotanical Remains from Site 15Le70 (Pine Crest Rockshelter), Lee County, Kentucky","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: History and archaeology","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"6.1"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"This paper uses the archaeobotanical assemblage from Site 15Le70, a multi-excavated and extensively looted rockshelter in eastern Kentucky, while opening new lines of inquiry into gendered labor and practice during the Archaic-Woodland transition. Because legacy collections are often dispersed across institutions and/or research projects, the materials from any single site may be fragmented, as was the case for 15Le70. Such collections can be overlooked, yet this investigation into 15Le70’s archaeobotanical assemblage demonstrates that partial or scattered datasets can yield meaningful results and hold the potential to fill gaps in the archaeological record left by looting.\n\nIn this study, a small sample (n=10) of 15Le70 was analyzed using the plant category system by Williams (2000), modified to highlight taxa culturally documented as having been collected and used to treat gynecological conditions. If women during the Archaic-Woodland transition were using rockshelters as women’s birthing and/or menstrual retreats, as suggested by current interpretations of ash-caves and nutprocessing sites, simultaneously with the development of agriculture, it is reasonable to ask whether they were also cultivating plants for gynecological needs, highlighting women’s labor and possible ritual expertise in the development of agriculture. While the limited sample cannot provide definitive proof and the results for Site 15Le70 remain inconclusive, the assemblage is consistent with women-linked activities identified in broader comparative research. This case demonstrates that even scattered legacy archaeobotanical collections can support new lines of inquiry, including a look at gendered labor and practice, to deepen understanding of the occupational periods at archaeological sites.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/interdes_finalprojects/3/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:24:17Z","registered":"2026-05-19T16:24:17Z","published":null,"updated":"2026-05-19T16:24:17Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.255","type":"dois","attributes":{"doi":"10.13023/etd.2026.255","identifiers":[],"creators":[{"name":"Chambers, Anyiah","nameType":"Personal","givenName":"Anyiah","familyName":"Chambers","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0000-2181-7077","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"STUDENTS AS INFORMATION RESPONDERS","titleType":null},{"lang":null,"title":"EXTENDING OUR UNDERSTANDING OF STUDENTS AT A PWI","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Media and communications","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.8"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"As school shootings continue to rise across the United States, understanding how students respond to and share information during crises has become a critical concern for higher education institutions. While prior research has examined the role of students as first information responders (FIRs) during emergencies, few studies have investigated how these processes unfold among Black and non-Black students at predominantly white institutions (PWIs). This mixed methods study is a replication and extension of Omilion-Hodges and Edwards (2021), examining how undergraduate Black and non-Black students at PWIs evaluate, construct, and disseminate crisis-related messages, particularly during active-shooter events. Grounded in channel specification theory (CST) and McCroskey and Teven’s (1999) source credibility framework, this research explores how students perceive message credibility, engage in information verification, and balance institutional trust with communal responsibility. Quantitative methods assess how credibility dimensions and participation in the experiment shape anxiety levels before and after the experiment, while qualitative methods explain the nuanced ways in which students frame and share crisis information across digital platforms. By centering the experiences of Black and non-Black students, this project addresses longstanding gaps in crisis communication literature and offers practical insights for developing culturally responsive, emotionally intelligent, and effective crisis messaging strategies in higher education.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Anyiah S. Chambers","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":"Pilot Project Small-Scale Funding, PI","funderName":"UNITE Research Priority Area","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"}],"url":"https://uknowledge.uky.edu/comm_etds/155/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:18:54Z","registered":"2026-05-19T16:18:54Z","published":null,"updated":"2026-05-19T16:18:54Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.192","type":"dois","attributes":{"doi":"10.13023/etd.2026.192","identifiers":[],"creators":[{"name":"Frank, George","nameType":"Personal","givenName":"George","familyName":"Frank","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0008-5087-2778","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"ADVANCING THE MELT SPINNING STABILITY OF MESOPHASE PITCH PRECURSORS FOR HIGH-MODULUS CARBON FIBER","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Materials engineering","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"2.5"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Carbon fiber is applicable for many structural applications that require a high strength-to-weight ratio. While the most common precursor to carbon fiber is polyacrylonitrile, carbon fibers made from mesophase pitch have niche applications where high thermal conductivity and exceptional stiffness are required. Mesophase pitch-derived carbon fibers typically stem from coal tar or the bottoms products from petroleum distillation, but there is an opportunity for lower-cost carbon fiber when the precursor pitch is a coal and petroleum oil liquefaction product. The aligned graphitic structure of these high-modulus carbon fibers originates from the orientation of liquid crystalline domains in mesophase pitch during melt spinning. A significant challenge to the production of mesophase pitch-derived carbon fibers is the melt spinning process. The short draw distance (\u003c 1 cm) of the molten filament creates high melt stress, causing greater susceptibility to failure-inducing instabilities. Mitigation of these instabilities is essential for scale-up to multifilament melt spinning on an industrial scale.\n\nDespite prior investigations into mesophase pitch melt spinning, critical gaps remain in understanding how mesophase characteristics and spinning conditions influence stability, particularly under conditions relevant to industrial-scale production. Mitigation of instabilities during melt draw can lead to fewer filament breakages and facilitate the production of carbon fiber. Therefore, this dissertation begins by investigating the mitigation of instabilities during melt spinning by focusing on the properties of the mesophase pitch. Then, challenges in economical scale-up of high modulus carbon fiber are explored by studying spinning stability under various multifilament melt spinning conditions and with coal extract-derived mesophase pitch.\n\nFirst, this work investigates the modification of coal tar-derived isotropic pitch, which is the amorphous precursor to liquid crystalline mesophase pitch. The isotropic domains in mesophase pitch form a heterogenous, bi-phasic system and are concerning due to their local viscosity differences compared to the adjacent mesophase domains. Previous works have explored how instabilities in mesophase pitch are more prevalent with increasing concentrations of isotropic domains. In this work, the isotropic domain size distribution of a mesophase pitch is varied while holding the isotropic content constant to study changes in the viscous flow through a capillary. Viscosity fluctuations within the capillary over time are correlated with instabilities in melt spinning. The distribution of isotropic domains is shown to change with time as the isotropic domains coalesce at the melt spinning temperature. Second, the storage conditions for the pitch are hypothesized to cause slow oxidation of the pitch, affecting the viscosity and spinning stability over several months. Oxygen content of pitch over time is studied while varying the pitch particle size and storage atmosphere. Correlation between oxygen content and melt spinning stability is investigated for pitches in air at an elevated temperature and at room temperature for long durations.\n\nThen, this work addresses the challenges of scale-up by investigating several processing variables of multifilament melt spinning, including air temperature outside the capillary, spinning temperature, mass flow rate, and spinneret capillary quality. The effects of these process variables on multifilament spinning stability are compared to those observed under similar conditions in single filament melt spinning. Lastly, this work focuses on lower cost precursors for producing mesophase pitch. Waste coal is a focus for this study as it has potential utility due to its high polycyclic aromatic content, high surface area for liquefaction, and no present market value. The properties of mesophase pitches derived from waste coal and petroleum decant oil liquefaction extract are compared to those derived from petroleum decant oil alone. Differences in melt spinning stability between these two mesophase pitches are investigated by contrasting their viscosity, molecular weight distribution, mass loss under melt spinning conditions, and SEM cross sections of the green filaments. The graphitic texture, mechanical properties, and overall yield of the graphitized carbon fibers derived from waste coal extract are compared to those derived from petroleum decant oil alone.\n\nIn conclusion, stable multifilament melt spinning was demonstrated, achieving 30 minutes of uninterrupted melt spinning for \u003e 90% of the spinneret capillaries while producing fiber with a diameter of approximately 20 µm. These are the first high modulus carbon fibers obtained utilizing waste coal as a feedstock, with 562 GPa modulus and 1.22 GPa tensile strength, and an overall yield to carbon fiber was improved by 75% compared to carbon fibers derived from petroleum decant oil alone.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 George Frank","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":"Contract","funderName":"Office of Fossil Energy and Carbon Management","awardNumber":"DE-AC05-00OR22725","funderIdentifier":"https://doi.org/10.13039/100020312","funderIdentifierType":"Crossref Funder ID"},{"awardUri":null,"awardTitle":null,"funderName":"U.S. Department of Energy","awardNumber":"DEFE0031796","funderIdentifier":"https://doi.org/10.13039/100000015","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/cme_etds/190/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:15:45Z","registered":"2026-05-19T16:15:45Z","published":null,"updated":"2026-05-19T16:15:45Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.280","type":"dois","attributes":{"doi":"10.13023/etd.2026.280","identifiers":[],"creators":[{"name":"Johnson, Lauren","nameType":"Personal","givenName":"Lauren","familyName":"Johnson","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0006-4596-6791","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"EQUID MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) EVOLUTION \u0026 GENOME ORGANIZATION","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Veterinary sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"4.3"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"The evolution of modern horses has a well-documented fossil record and has long been of interest to the genetics community. Although non-caballine equids (e.g. zebras, donkeys, and asses) can hybridize with horses, the resulting offspring are typically infertile. Despite these reproductive barriers, genomic analyses reveal regions of high sequence similarity among equid species. This dissertation investigates the role of historical introgression in the evolution of modern Equus species. The first chapter re-evaluates earlier findings derived from a limited horse population and a single reference genome. The variants of the identified regions were pushed through Ensembl’s Variant Effect Predictor to assess the possible consequences. Three consistent patterns emerged: an overrepresentation of conserved regions on chromosome 20, which contains the major histocompatibility complex (MHC), a higher density of conserved regions on smaller chromosomes, and many of the conserved regions occurred in introns. Building on these patterns, the following chapter examined the functional consequences of MHC alleles identified within regions of high sequence similarity. Of the 50 loci identified within the MHC superlocus, 12 had the assumed pattern of introgression. A region in DR-beta2 gene (Thoroughbred T2T with donkeys only) dataset had coding consequences. The other 11 loci are hypothesized to be involved with expression of the complexes. However, timing of the introgression event(s) is still unknown and are part of a future project. The final chapter investigates chromosomal rearrangements in equids using pan-genome graph representations. Previous work was able to decipher the large rearrangements between species at the karyotypic level and SNVs gave more information about their evolutionary relationships. However, the pan-genome graphs were able to compare three publicly available reference genomes and verify previous results. Another aspect of the pan-genome graphs is the ability to study large structural variants to single nucleotide polymorphisms between species for molecular evolution. Together, these analyses provide new insight into the molecular evolution of equids—particularly at the DR-beta2 locus—and establish a framework for applying evolutionary genomics to conservation and future gene-editing efforts.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Lauren C. Johnson","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"Keeley M. Hagan \u0026 Louis D. Lieto Fellowship","awardNumber":null,"funderIdentifier":null,"funderIdentifierType":"Other"}],"url":"https://uknowledge.uky.edu/gluck_etds/75/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:11:48Z","registered":"2026-05-19T16:11:49Z","published":null,"updated":"2026-05-19T16:11:49Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.219","type":"dois","attributes":{"doi":"10.13023/etd.2026.219","identifiers":[],"creators":[{"name":"Hannah Grace Childress","nameType":"Personal","givenName":"Hannah Grace Childress","familyName":null,"affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0002-4463-6265","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"BUILDING INCLUSIVE AGRICULTURE","titleType":null},{"lang":null,"title":"DEVELOPING TRAINING PROGRAMS FOR YOUTH IN THE LIVESTOCK INDUSTRY TO SUPPORT DISABILITY INCLUSION THROUGH THE 2025 SUNSHINE CLASS","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Educational sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.3"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"RPRT","bibtex":"article","citeproc":"article-journal","schemaOrg":"ScholarlyArticle","resourceType":"Master's Thesis","resourceTypeGeneral":"Text"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Throughout history, individuals with disabilities have not been provided the same opportunities at the same rigor as their peers. However, many industries work diligently to provide means for individuals with disabilities to be incorporated into events. To mitigate this issue, disability-inclusive livestock events have begun to form across the country, where 4-H and FFA members mentor individuals with disabilities. Even with the inclusion of all individuals, this overshadows the mentor's lack of previous collaboration and knowledge about disabilities. This qualitative study examined mentors’ self-efficacy before and after volunteering for the 2025 Sunshine class, while participating in a disability awareness training program. Based on participants' responses from the semi-structured interviews, it was found that the mentor’s four pillars of self-efficacy (mastery experiences, vicarious experiences, social persuasion, emotional and psychological feedback) had a greater influence on their self-belief than the disability training. It was also established that participants' attitudes and beliefs about inclusion were pre-established based on personal influences. Even though the training did not leave a drastic impact on mentors, it was still a recognized tool that participants reflected on. Based on this study, youth development programs should consider implementing longer disability awareness interventions to increase self-efficacy.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Hannah Grace Childress","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/cld_etds/82/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T16:08:58Z","registered":"2026-05-19T16:08:58Z","published":null,"updated":"2026-05-19T16:08:58Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.205","type":"dois","attributes":{"doi":"10.13023/etd.2026.205","identifiers":[],"creators":[{"name":"Calvache Garcia, Daniela","nameType":"Personal","givenName":"Daniela","familyName":"Calvache Garcia","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0009-0004-2122-3681","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"Visual Genealogies of Disability in Mexican Visual Culture","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Other social sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.9"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Disability in Mexico is a visually constructed category, shaped by a long genealogy of representation in which images of bodily difference actively participate in defining power and the management of all bodies. The discursive forces that define disability as unproductivity reduce body-minds to the service of the economic system, affecting our relationship with death, illness, reproduction, size, youth, and beauty. Across the Mesoamerican visual space, such representations have long unsettled dominant systems of truth about bodies. This dissertation examines how conceptions of disability are produced, negotiated, and reimagined through three historical moments and cultural expressions: Pre-Hispanic Mayan imagery, Mexican colonial codices, and modern Mexican votive paintings. Drawing on feminist, decolonial, and counter-ableist perspectives, I argue that these conceptions are continuously updated through visual genealogies that echo the past, shaping how disability is seen, interpreted, and lived.\n\nMoving from Pre-Columbian Maya and Olmec cosmologies, where physical difference is constitutive of creation and divinity, through the colonial reconfiguration of indigenous understandings of illness in Mexican codices, to modern votive paintings where medical and religious discourses compete in shaping cultural perceptions of vulnerability, the dissertation traces how difference has been persistently visualized, disciplined, and reimagined, demonstrating that disability cannot be understood apart from the visual histories that continue to produce it.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Daniela Calvache Garcia","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/hisp_etds/71/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T15:24:19Z","registered":"2026-05-19T15:24:19Z","published":null,"updated":"2026-05-19T15:24:19Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.202","type":"dois","attributes":{"doi":"10.13023/etd.2026.202","identifiers":[],"creators":[{"name":"Reis, Alex","nameType":"Personal","givenName":"Alex","familyName":"Reis","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0002-5257-3463","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"Understanding the Drivers of Marine Sediment Diagenesis in Carbonate-Bearing Sediments","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Earth and related environmental sciences","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"1.5"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Marine sediments serve as an important geochemical record used to study how the Earth’s climate and oceans have changed throughout geologic time. As such, it is critical to understand how these sediments can be altered following deposition on the seafloor. This dissertation targeted two key geochemical archives, carbonate and pyrite, to link changing burial conditions with the resulting marine sediment chemistry. In particular, primary carbonate minerals record several indicators of past ocean chemistry, while pyrite preserves information related to the redox state of the sediment during deposition and burial. Additionally, secondary processes associated with changes in pore fluid chemistry and redox state can alter sediment chemistry, beginning at the sediment-water interface and extending deep into the buried sediment. This dissertation was divided into three papers addressing these questions at two ocean drilling sites, IODP Site U1153 on the Southern Campbell Plateau and ODP Site 1172 on the East Tasman Plateau. The first study examined how a 26-million-year unconformity at IODP Site U1553 impacted the chemistry of carbonate sediments in the region. The unconformity at this site resulted in the exposure of older sediments to more recent seawater which could lead to alteration of the carbonate minerals. This study used a combination of bulk sediment chemistry, pore water chemistry, and isotopic indicators to investigate the effects of this unconformity on the shallow burial conditions in the region. Pore water analyses showed expanded manganese, iron, and sulfate reduction windows which are attributed to the low total organic content limiting the influence of redox processes on the sediments. The sulfur isotope analyses in the pore water sulfate and carbonate associated sulfate (CAS) showed no correlation. This indicates there is likely little to no interaction between the sulfate in the CAS and pore fluids. This suggests the influence of more recent pore waters intruding into the older rocks is limited and the CAS record is resistant to alteration as burial conditions change through time. The second study built on the first by examining the influence the expanded redox zones had on the deep-burial conditions at IODP Site U1553. The presence of dissolved sulfate at depths \u003e400 mbsf and abundant methane below 520 mbsf suggests the presence of a deeply buried (\u003e500 mbsf) sulfate-methane transition zone (SMTZ). This study used sulfur isotopes in chromium reducible sulfur and bulk sediment geochemistry to identify the modern SMTZ as well as three intervals where the SMTZ was in the past. The apparent upward migration of the STMZ suggests that the changing conditions at the sediment-water interface may play a role in controlling the depth of the SMTZ over time if it impacts the sulfate supply. Deeply buried SMTZs are poorly understood, however, they may play an important role in the carbon and sulfur cycles in marine sediments. The third study examined carbonate sediments and pore waters on the East Tasman Plateau to evaluate how carbonate recrystallization rates vary around the Tasman Gateway. Carbonate minerals are highly susceptible to rapid alteration shortly after burial as the minerals are converted into more stable forms such as low-Mg calcite. This study examined these processes at ODP Site 1172 using the analysis of δ44Ca, 87Sr/86Sr, as well as bulk carbonate sediment and pore water chemistry. Based on the dissolved Sr profile at this site and comparisons with published results from ODP Sites 1170 and 1171, the pore water δ44Ca at Site 1172 should have equilibrated with those in the carbonate sediment around 20-25 mbsf. However, they do not equilibrate until 120 mbsf. This suggests that short-term recrystallization at this site is much slower than anticipated. The Sr composition indicates the longer-term recrystallization rate should align with other sites. This highlights the need for further study of how carbonate minerals are affected by alteration following deposition.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Alex Reis","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[{"awardUri":null,"awardTitle":null,"funderName":"United States Science Support Program","awardNumber":null,"funderIdentifier":"https://doi.org/10.13039/100012018","funderIdentifierType":"Crossref Funder ID"}],"url":"https://uknowledge.uky.edu/ees_etds/124/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T15:19:51Z","registered":"2026-05-19T15:19:51Z","published":null,"updated":"2026-05-19T15:19:51Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.154","type":"dois","attributes":{"doi":"10.13023/etd.2026.154","identifiers":[],"creators":[{"name":"Arsenault, Nicholas DJ","nameType":"Personal","givenName":"Nicholas DJ","familyName":"Arsenault","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[]}],"titles":[{"lang":null,"title":"Local Energy Decay for Non-stationary Damped Wave Operators","titleType":null}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Mathematics","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"1.1"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"This work establishes integrated local energy decay (ILED) estimates for the damped wave equation on certain non-stationary spacetimes. The main technical result is a high frequency estimate that holds in great generality, provided that null geodesics trapped in a compact region are sufficiently damped. This is combined with low- and medium-frequency estimates to establish full local energy decay. We conclude by providing a counterexample where the damping assumption fails and local energy decay does not hold.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 Nicholas DJ Arsenault","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/math_etds/131/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T15:10:30Z","registered":"2026-05-19T15:10:31Z","published":null,"updated":"2026-05-19T15:10:31Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}},{"id":"10.13023/etd.2026.224","type":"dois","attributes":{"doi":"10.13023/etd.2026.224","identifiers":[],"creators":[{"name":"Fey, McKenna","nameType":"Personal","givenName":"McKenna","familyName":"Fey","affiliation":[{"name":"University of Kentucky","schemeUri":"https://ror.org","affiliationIdentifier":"https://ror.org/02k3smh20","affiliationIdentifierScheme":"ROR"}],"nameIdentifiers":[{"schemeUri":"https://orcid.org","nameIdentifier":"https://orcid.org/0000-0003-4644-2069","nameIdentifierScheme":"ORCID"}]}],"titles":[{"lang":null,"title":"German Couples' Mental and Relational Health Before, During, and After Pregnancy","titleType":null},{"lang":null,"title":"Comparisons Across Conception Type","titleType":"Subtitle"}],"publisher":"University of Kentucky Libraries","container":{},"publicationYear":2026,"subjects":[{"subject":"FOS: Sociology","schemeUri":"https://web-archive.oecd.org/2012-06-15/138575-38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)","classificationCode":"5.4"}],"contributors":[],"dates":[],"language":null,"types":{"ris":"THES","bibtex":"phdthesis","citeproc":"thesis","schemaOrg":"Thesis","resourceTypeGeneral":"Dissertation"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[],"descriptions":[{"lang":null,"description":"Previous research on the perinatal period (i.e., pregnancy and postpartum) has largely focused on the pregnant partner’s experience and has rarely involved dyadic data from both partners in a romantic relationship. Although mental health—particularly of pregnant partners—has been extensively studied, relational health is often overlooked in the literature. Using life course theory as a framework, the present study examines both pregnant and nonpregnant partners’ mental and relational health before, during, and after pregnancy to understand actor, partner, and cross-process effects. Six hundred and twelve couples (N = 1,224 individuals) from the German Family Panel (pairfam) were assessed for mental and relational health at three timepoints: before, during, and after pregnancy. A cross-lagged actor-partner interdependence model revealed that pre-pregnancy and prenatal mental health predict later mental health among both pregnant and nonpregnant partners, and that pre-pregnancy and prenatal relational health predict later relational health in both partners (i.e., actor effects). Relational health has a unique positive effect on partners’ perinatal mental and relational health, where nonpregnant partners’ relational health predicted the pregnant partners’ later mental and relational health, and pregnant partners’ pre-pregnancy relational health predicted the nonpregnant partners’ prenatal mental health (i.e., partner effects). There appeared some nuanced differences in partner effects when comparing couples who had (a) expected, spontaneous pregnancies; (b) unexpected pregnancies; and (c) pregnancies after infertility or fertility treatment. Specifically, nonpregnant partners’ prenatal mental health predicted their own postpartum mental health among those with expected, spontaneous pregnancies and those with unexpected pregnancies and predicted the pregnant partners’ postpartum mental health among those who became pregnant after infertility or fertility treatment. The results of the present study provide support for including both partners in the prevention, assessment, and treatment of pregnant and postpartum individuals’ perinatal health.","descriptionType":"Abstract"},{"lang":null,"description":"© 2026 McKenna Fey","descriptionType":"Other"}],"geoLocations":[],"fundingReferences":[],"url":"https://uknowledge.uky.edu/hes_etds/127/","contentUrl":null,"metadataVersion":0,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"fabricaForm","isActive":true,"state":"findable","reason":null,"viewCount":0,"downloadCount":0,"referenceCount":0,"citationCount":0,"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2026-05-19T15:05:10Z","registered":"2026-05-19T15:05:11Z","published":null,"updated":"2026-05-19T15:05:11Z"},"relationships":{"client":{"data":{"id":"uky.lib","type":"clients"}}}}],"meta":{"total":5818,"totalPages":233,"page":1},"links":{"self":"https://api.datacite.org/dois?affiliation=true\u0026affiliation-id=02k3smh20","next":"https://api.datacite.org/dois?affiliation-id=02k3smh20\u0026affiliation=true\u0026page%5Bnumber%5D=2\u0026page%5Bsize%5D=25"}}