10.6084/m9.figshare.c.3631430_D5
Erez Nitzan
Oshri Avraham
Nitza Kahane
Shai Ofek
Deepak Kumar
Chaya Kalcheim
Additional file 3: Figure S3. of Dynamics of BMP and Hes1/Hairy1 signaling in the dorsal neural tube underlies the transition from neural crest to definitive roof plate
caBMPR1A/caAlk3 stimulates ectopic pSMAD activity. (A–A”) Electroporation of control GFP (PBI-GFP) or caBMPR1a-GFP-PBI (B–B”) followed by pSMAD immunostaining. Note in A–A” that the pSMAD signal is restricted to the dorsal NT even if the transfection attains half of the NT length. In contrast, caBMPR1a/Alk3 induces ectopic pSMAD activity in transfected cells throughout the electroporated domain (B–B”). Bar = 50 μM. (JPG 516 kb)
Cell Biology
Genetics
Molecular Biology
Neuroscience
Developmental Biology
110309 Infectious Diseases
Figshare
2016
2016-12-15
2016-12-15
Figure
529023 Bytes
10.1186/s12915-016-0245-6
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