10.6084/M9.FIGSHARE.21592783.V1
Lihua Wang
Lihua
Wang
Affiliated Eye Hospital of Wenzhou Medical College
Zheng Zhu
Zheng
Zhu
Ruijin Hospital
Qi Liang
Qi
Liang
Wenzhou Medical University
Yecheng Tao
Yecheng
Tao
Zhejiang University
Gaowei Jin
Gaowei
Jin
Wenzhou Medical University
Yaoyao Zhong
Yaoyao
Zhong
Wenzhou Medical University
Jichen Dai
Jichen
Dai
Wenzhou Medical University
Ruixia Dai
Ruixia
Dai
Wenzhou Medical University
Zhixiang Wang
Zhixiang
Wang
Wenzhou Medical University
Junbo Chen
Junbo
Chen
Wenzhou Medical University
Lingjie Zhou
Lingjie
Zhou
Wenzhou Medical University
Shouyu Ke
Shouyu
Ke
Wenzhou Medical University
Bin Zheng
Bin
Zheng
Wenzhou Medical University
Linhua Lan
Linhua
Lan
First Affiliated Hospital of Wenzhou Medical University
Xiaokun Lin
Xiaokun
Lin
0000-0001-6706-5309
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
Tongke Chen
Tongke
Chen
Wenzhou Medical University
Additional file 9 of A novel small molecule glycolysis inhibitor WZ35 exerts anti-cancer effect via metabolic reprogramming
Additional file 9: Figure S9. (A and C) Time-dependent ROC curves analyzing the potential value of expression levels of SLC2A1 (A) and combination of SLC2A1 and YAP1 (C) in diagnosis of liver cancer. (B and D) Kaplan–Meier analysis displaying survival rate for liver cancer samples from GEO datasets according to the expression levels of single factor of SLC2A1 (B) (P = 0.00035) and multi factors of YAP1 and SLC2A1 (D) (P < 0.0001). High integrated expression levels of YAP1 and SLC2A1 were related to the poor survival and prognosis. (E) Kaplan-Meier approach visualized the relationship between the expression of YAP and OS in liver cancer patients (n = 53, P = 0.0018). (F) ROC calibration plots of the nomogram for combined YAP and GLUT1:The AUC was 0.889. (G) ROC calibration plots of the nomogram for GLUT1: The AUC was 0.775.
Biochemistry
Medicine
Cell Biology
Physiology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Virology
figshare
2022
2022-11-21
2024-02-08
Figure
660096 Bytes
10.6084/m9.figshare.21592783
10.3322/caac.21660
10.1016/j.cell.2016.12.039
10.1016/j.cell.2015.08.016
10.1016/j.semcancer.2017.12.011
10.1074/jbc.M300608200
10.1038/sj.bjc.6601269
10.1111/jog.13867
10.1002/pro.2858
10.2337/diacare.13.3.198
10.3346/jkms.2000.15.4.420
10.1158/0008-5472.CAN-20-2870
10.7150/thno.29864
10.1016/j.canlet.2018.11.030
10.1245/s10434-018-6357-1
10.1016/j.bbcan.2022.188756
10.1038/ncb3216
10.7554/eLife.67312
10.7554/eLife.67312
10.1016/j.cell.2007.07.019
10.1101/gad.1726608
10.1016/j.cell.2011.02.013
10.1186/s13046-019-1352-3
10.1016/j.cmet.2018.07.010
10.1039/C8FO00314A
10.1016/j.fct.2020.111131
10.1039/C8FO02448K
10.1186/s13046-019-1424-4
10.15252/embj.2018100294
10.15252/embj.2018100294
10.18632/oncotarget.3333
10.1093/nar/gky1095
10.1038/s41419-020-2309-3
10.3389/fnmol.2018.00165
10.1038/cdd.2014.150
10.1371/journal.pmed.1001624
10.1038/nrc3038
10.1016/j.ccell.2016.05.016
10.1038/s41568-018-0061-0
10.1016/j.eururo.2019.01.015
10.1182/blood-2016-10-569186
10.1038/s41573-020-0070-z
10.1038/s41580-018-0086-y
10.1038/nature20602
10.1172/JCI150595
10.1172/JCI150595
10.1016/j.cell.2007.05.009
10.1186/1476-4598-12-152
10.1016/j.immuni.2011.09.021
10.1158/1078-0432.CCR-17-3167
10.1038/ncb3039
10.1371/journal.pone.0004715
10.1016/j.molcel.2014.10.027
10.1186/s12967-022-03758-0
CC BY + CC0