10.6084/M9.FIGSHARE.21559174.V1
Apolline Imbard
Apolline
Imbard
0000-0002-0420-8322
Hôpital Necker-Enfants Malades
Hôpital Robert-Debré
University of Paris-Saclay
Artemis Toumazi
Artemis
Toumazi
Hôpital Robert-Debré
Inserm
Sophie Magréault
Sophie
Magréault
Hôpital Jean-Verdier
Inserm
Nuria Garcia-Segarra
Nuria
Garcia-Segarra
Hôpital Robert-Debré
University Hospital of Lausanne
Dimitri Schlemmer
Dimitri
Schlemmer
Hôpital Robert-Debré
Florentia Kaguelidou
Florentia
Kaguelidou
Hôpital Robert-Debré
Inserm
Isabelle Perronneau
Isabelle
Perronneau
Hôpital Robert-Debré
Jérémie Haignere
Jérémie
Haignere
Hôpital Robert-Debré
Hélène Ogier de Baulny
Hélène Ogier
de Baulny
Hôpital Robert-Debré
Alice Kuster
Alice
Kuster
University of Nantes
François Feillet
François
Feillet
Inserm
Corinne Alberti
Corinne
Alberti
Hôpital Robert-Debré
Sophie Guilmin-Crépon
Sophie
Guilmin-Crépon
Hôpital Robert-Debré
Inserm
Jean-François Benoist
Jean-François
Benoist
Hôpital Necker-Enfants Malades
Hôpital Robert-Debré
University of Paris-Saclay
Manuel Schiff
Manuel
Schiff
Hôpital Necker-Enfants Malades
Hôpital Robert-Debré
Université Paris-Cité
Additional file 1 of Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial
Additional file 1: Table S1: Patients’ characteristics. Table S2: Detail of patient current treatment. Table S3: Clinical data at inclusion. Figure S1: Carry-over effect. Figure S2: plasma total homocysteine (tHcy) before and after one month treatment with 100 mg/kg/day) (A, D) or 250 mg/kg/day (B, E) in pnrCBS patients (A, B) and cblC patients (B, E) and the corresponding difference (ΔtHcy) for each pnrCBS (C) and cblC (F) patient. Figure S3: SAM (A, B), SAH (C, D) and the SAM/SAH ratio (E, F) after 1 month of treatment at 100 mg/kg (light grey) or 250 mg/kg (dark grey) of betaine in CBS (on left) and cblC patients (on right).
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figshare
2022
2022-11-15
2024-02-07
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10.6084/m9.figshare.21559174
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