10.6084/M9.FIGSHARE.21542889
Meng-Ting Li
Meng-Ting
Li
Jia Wang
Jia
Wang
Jia Hu
Jia
Hu
Han-Biao Wu
Han-Biao
Wu
Wei-Shang Deng
Wei-Shang
Deng
Zhi-Kun Qiu
Zhi-Kun
Qiu
Ji-Sheng Chen
Ji-Sheng
Chen
Comparative efficacy and safety of antiviral traditional Chinese medicine injections for viral pneumonia: a systematic review and network meta-analysis
<p>Viral pneumonia (VP) is becoming a persistent and pervasive burden of disease. Traditional Chinese medicine Injections (TCMIs) have been proved effective in the treatment of patients with VP, which are now widely used in China. The evidence of TCMIs for VP is evolving rapidly. This study aims to assess the comparative efficacy and safety of TCMIs to provide more evidence and sights for the treatment selection of VP.</p> <p>Seven databases were searched from their inception up to 16 March 2022. Only randomized controlled trials (RCTs) are included to compare the efficacy and safety of antiviral TCMIs for the treatment of viral pneumonia. Clinical efficacy and rate of adverse events were considered as primary outcomes.</p> <p>A total of 76 RCTs with eight TCMIs comprising 7925 patients were included in the NMA. According to NMA, Reduning Injection combined with conventional antiviral drugs (CAD) produced superior effects in the effective outcomes and reduced the adverse event incidence rate of VP.</p> <p>This study indicated that TCMIs combined with CAD was more effective and safer than CAD monotherapy and compared different TCMIs therapies, which provided guidance and reference for the selection of clinical treatment medication.</p>
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer
Science Policy
Infectious Diseases
Taylor & Francis
2022
2022-11-11
2023-05-31
Dataset
343263 Bytes
10.1080/14787210.2022.2142119
CC BY 4.0