10.6084/M9.FIGSHARE.21385915.V1
Nils Bröckelmann
Nils
Bröckelmann
University of Freiburg
Julia Stadelmaier
Julia
Stadelmaier
University of Freiburg
Louisa Harms
Louisa
Harms
University of Freiburg
Charlotte Kubiak
Charlotte
Kubiak
University of Freiburg
Jessica Beyerbach
Jessica
Beyerbach
University of Freiburg
Martin Wolkewitz
Martin
Wolkewitz
University of Freiburg
Jörg J. Meerpohl
Jörg J.
Meerpohl
University of Freiburg
Lukas Schwingshackl
Lukas
Schwingshackl
0000-0003-3407-7594
University of Freiburg
Additional file 1 of An empirical evaluation of the impact scenario of pooling bodies of evidence from randomized controlled trials and cohort studies in medical research
Additional file 1: Appendix S1. Search strategy. Tables S1-S5. Table S1. Explanation and definition for PI/ECO similarity degree. Table S2. PI/ECO similarity degree. Table S3. Differences between published (reported) effect estimates and re-calculated effect estimates. Table S4. Reason for exclusion from the pooling scenario. Table S5. Pooling results. Figures S1-S118. Fig S1. Forest plot: Low sodium (Intervention/Exposure); All-cause mortality (Outcome). Fig. S2. Forest plot: Low sodium; Cardiovascular disease. Fig. S3. Forest plot: Intra-aortic balloon pump; All-cause mortality. Fig. S4. Forest plot: Self-administered therapy; Treatment success. Fig S5. Forest plot: Self-administered therapy; Treatment completion. Fig. S6. Forest plot: Self-administered therapy; All-cause mortality. Fig S7. Forest plot: Antiretroviral therapy; HIV infection. FigS8-Forest plot: Nonnutritive sweeteners; Body Mass Index random sequence. Fig. S9. Forest plot: Surgical abortion by mid-level providers; Failure or incomplete abortion. Fig. S10. Forest plot: Surgical abortion by mid-level providers; Complications. Fig. S11. Forest plot: Surgical abortion by mid-level providers; Abortion failure and complications. Fig. S12. Forest plot: Clopidogrel pretreatment for percutaneous coronary intervention; All-cause mortality. Fig. S13. Forest plot: Clopidogrel pretreatment for percutaneous coronary intervention; Major bleeding. Fig. S14. Forest plot: Clopidogrel pretreatment for percutaneous coronary intervention; Coronary heart disease. Fig. S15. Forest plot: P2Y12 inhibitor pretreatment in non-ST elevation acute coronary syndrome; All-cause mortality. Fig. S16. Forest plot: P2Y12 inhibitor pretreatment in non-ST elevation acute coronary syndrome; Major bleeding. Fig. S17. Forest plot: P2Y12 inhibitor pretreatment in non-ST elevation acute coronary syndrome; Main composite ischemic endpoint. Fig. S18. Forest plot: Mediterranean diet; Breast cancer. Fig. S19. Forest plot: High calcium; All fractures. Fig. S20. Forest plot: High calcium; Verterbral fractures. Fig. S21. Forest plot: High calcium; Hip fracture. Fig. S22. Forest plot: Sigmoidoscopy; Colorectal cancer mortality. Fig. S23. Forest plot: Sigmoidoscopy; Colorectal cancer incidence. Fig. S24. Forest plot: High omega-3; Cerebrovascular disease. Fig. S25. Forest plot: High α-linolenic acid; Coronary heart disease. Fig. S26. Forest plot: High omega-3; Coronary heart disease. Fig. S27. Forest plot: Omega-6; Coronary heart disease. Fig. S28. Forest plot: High calcium; Cardiovascular mortality. Fig. S29. Forest plot: High dairy; Systolic blood pressure. Fig. S30. Forest plot: Radiation therapy; Erectile dysfunction. Fig. S31. Forest plot: Radical prostatectomy; Urinary incontinence. Fig. S32. Forest plot: Radical Prostatectomy; Erectile dysfunction. Fig. S33. Forest plot: Disease-modifying drugs; Conversion to clinically definite multiple sclerosis. Fig. S34. Forest plot: Extracranial-intracranial arterial bypass; All-cause mortality. Fig. S35. Forest plot: Extracranial-intracranial arterial bypass; Stroke. Fig. S36. Forest plot: Extracranial-intracranial arterial bypass; Stroke mortality or dependency. Fig. S37. Forest plot: Transcatheter aortic valve implantation; Early all-cause mortality. Fig. S38. Forest plot: Transcatheter aortic valve implantation; Mid-term all-cause mortality. Fig. S39. Forest plot: Transcatheter aortic valve implantation; Long-term all-cause mortality. Fig. S40. Forest plot: Treating gestational diabetes mellitus; High birth weight. Fig. S41. Forest plot: Treating gestational diabetes mellitus; Large-for-gestational age neonate. Fig. S42. Forest plot: Treating gestational diabetes mellitus; Shoulder dystocia. Fig. S43. Forest plot: Treating asymptomatic bacteriuria; Pyelonephritis. Fig. S44. Forest plot: Bacillus Calmette-Guérin vaccination; All-cause mortality. Fig. S45. Forest plot: Measles containing vaccines; All-cause mortality. Fig. S46. Forest plot: Total hip arthroplasty; Reoperation. Fig. S47. Forest plot: Total hip arthroplasty; Dislocation. Fig. S48. Forest plot: Total hip arthroplasty; Deep infection. Fig. S49. Forest plot: Chest-compression-only cardiopulmonary resuscitation; Survival. Fig. S50. Forest plot: Non-calcium-based phosphat binders; All-cause mortality. Fig. S51. Forest plot: Parenteral influenza vaccine; Influenza-like illness. Fig. S52. Forest plot: Parenteral influenza vaccine Influenza. FigS53-Forest plot: Inactivated influenza vaccines; Influenza. Fig. S54. Forest plot: Inactivated influenza vaccines; Influenza-like illness. Fig. S55. Forest plot: High total flavonoids; Colorectal neoplasms. Fig. S56. Forest plot: Transfusion; All-cause mortality. Fig. S57. Forest plot: Caesarean section; Urinary incontinence. Fig. S58. Forest plot: Caesarean section; Fecal incontinence. Fig. S59. Forest plot: Antiretroviral therapy by nurses; All-cause mortality. Fig. S60. Forest plot: Antiretroviral therapy by nurses; Attrition. Fig. S61. Forest plot: Nurses for maintenance of antiretroviral therapy; All-cause mortality. Fig. S62. Forest plot: Exenatide; Acute pancreatitis. Fig. S63. Forest plot: DDP-4 inhibitors; Heart failure. Fig. S64. Forest plot: DDP-4 inhibitors; Hospital admission for heart failure. Fig. S65. Forest plot: Tamoxifen; Heart failure. Fig. S66. Forest plot: SGLT-2 inhibitors; Acute kidney injury. Fig. S67. Forest plot: Erythropoiesis stimulating agents; Venous thromboembolism. Fig. S68. Forest plot: Erythropoiesis stimulating agents; All-cause mortality. Fig. S69. Forest plot: Pneumococcal polysaccharide vaccines; Invasive pneumococcal disease. Fig. S70. Forest plot: Neoral (Cyclosporin); Acute rejection of kidney transplant. Fig. S71. Forest plot: Early intervention for NSTE-ACS; All-cause mortality. Fig. S72. Forest plot: Early intervention for NSTE-ACS; Myocardial infarction. Fig. S73. Forest plot: Early intervention for NSTE-ACS; Major bleeding. Fig. S74. Forest plot: Caesarean section; Anal incontinence; feces. Fig. S75. Forest plot: Caesarean section; Anal incontinence; flatus. Fig. S76. Forest plot: Ceramic-on-ceramic bearings for total hip arthroplasty; Harris Hip Score. Fig. S77. Forest plot: High-flexion total knee arthroplasty; Flexion in degrees. Fig. S78. Forest plot: Gender-specific total knee arthroplasty; Flexion-extension range. Fig. S79. Forest plot: Second generation antipsychotics; Sedation. Fig. S80. Forest plot: Second generation antipsychotics; Neurologic outcomes. Fig. S81. Forest plot: Surgery for achilles tendon rupture; Re-rupture. Fig. S82. Forest plot: Surgery for achilles tendon rupture; Complications. Fig. S83. Forest plot: High vitamin D; Hypertension. Fig. S84. Forest plot: Carotid endarterectomy; Ipsilateral stroke. FigS85-Forest plot: Carotid endarterectomy; Stroke. Fig. S86. Forest plot: Carotid artery stenting; Periprocedural stroke. Fig. S87. Forest plot: Nasal deconolization; Surgical site infection. Fig. S88. Forest plot: Glycopeptide prophylaxis; Surgical site infection. Fig. S89. Forest plot: Enoxaparin; All-cause mortality. Fig. S90. Forest plot: Enoxaparin; Major bleeding. Fig. S91. Forest plot: Enoxaparin; All-cause mortality or myocardial infarction. Fig. S92. Forest plot: Antiretroviral therapy; Tuberculosis infection. Fig. S93. Forest plot: High sugar intake; Weight gain. Fig. S94. Forest plot: High sugar intake; Body Mass Index. Fig. S95. Forest plot: Influenza vaccines; Influenza-like illness. Fig. S96. Forest plot: Mefloquine; Discontinuation due to adverse effects. Fig. S97. Forest plot: Mefloquine; Serious adverse events or effects. Fig. S98. Forest plot: Mefloquine; Nausea. Fig. S99. Forest plot: Live-attenuated zoster vaccines; Suspected Herpes Zoster. Fig. S100. Forest plot: High selenium; Cancer. Fig. S101. Forest plot: High selenium; Cancer mortality. FigS102-Forest plot: High selenium; Colorectal cancer. FigS103-Forest plot: Training for traditional birth attendants/ assistance by traditional birth attendants; Perinatal mortality. Fig. S104. Forest plot: Training for traditional birth attendants/ assistance by traditional birth attendants; Neonatal mortality. Fig. S105. Forest plot: Unicompartimental knee arthroplasty; Venous thromboembolism. Fig. S106. Forest plot: Unicompartimental knee arthroplasty; Flexion-extension range. Fig. S107. Forest plot: Unicompartimental knee arthroplasty; Operation duration. Fig. S108. Forest plot: Recombinant factor VII; All-cause mortality. Fig. S109. Forest plot: Recombinant factor VII; Thromboembolism. Fig. S110. Forest plot: Everolimus-eluting bioresorbable vascular scaffold; Stent thrombosis. Fig. S111. Forest plot: Everolimus-eluting bioresorbable vascular scaffold; All-cause mortality. Fig. S112. Forest plot: Everolimus-eluting bioresorbable vascular scaffold; Coronary heart disease mortality. Fig. S113. Forest plot: Percutaneous coronary intervention; All-cause mortality. Fig. S114. Forest plot: Percutaneous coronary intervention; Cardiovascular mortality. Fig. S115. Forest plot: Percutaneous coronary intervention; Myocardial infarction. Fig. S116. Forest plot: Digoxin; All-cause mortality. Fig. S117. Forest plot: Digoxin; Cardiovascular mortality. Fig. S118. Forest plot: Digoxin; Hospital admission.
Medicine
Biotechnology
19999 Mathematical Sciences not elsewhere classified
Cancer
Science Policy
Computational Biology
figshare
2022
2022-10-24
2022-10-24
Journal contribution
3563087 Bytes
10.1186/s12916-022-02559-y
10.6084/m9.figshare.21385915
CC BY + CC0