10.6084/M9.FIGSHARE.21385910.V1
Zhiyu Wu
Zhiyu
Wu
Peking University
Lu Chen
Lu
Chen
Peking University
Xuanming Hong
Xuanming
Hong
Peking University
Jiahui Si
Jiahui
Si
Peking University
Weihua Cao
Weihua
Cao
Peking University
Canqing Yu
Canqing
Yu
Peking University
Tao Huang
Tao
Huang
Peking University
Dianjianyi Sun
Dianjianyi
Sun
Peking University
Chunxiao Liao
Chunxiao
Liao
Peking University
Yuanjie Pang
Yuanjie
Pang
Peking University
Zengchang Pang
Zengchang
Pang
Liming Cong
Liming
Cong
Zhejiang Center for Disease Control and Prevention
Hua Wang
Hua
Wang
Xianping Wu
Xianping
Wu
Sichuan Center for Disease Control and Prevention
Yu Liu
Yu
Liu
Yu Guo
Yu
Guo
Fuwai Hospital
Zhengming Chen
Zhengming
Chen
University of Oxford
Jun Lv
Jun
Lv
Peking University
Ministry of Education of the People's Republic of China
Wenjing Gao
Wenjing
Gao
Peking University
Liming Li
Liming
Li
Peking University
Additional file 1 of Temporal associations between leukocytes DNA methylation and blood lipids: a longitudinal study
Additional file 1: Table S1. Details of sample size and quality control. Figure S1. Manhattan plots of the epigenome-wide association study (Model 1). Manhattan plots for (a) triglyceride (TG), (b) total cholesterol (TC), (c) high-density lipoprotein-cholesterol (HDL-C), and (d) low-density lipoprotein-cholesterol (LDL-C) in Model 1. The red horizontal dashed lines represent the FDR-adjusted threshold of significance. Table S2. Associations between DNA methylation and lipid measures (Model 2). Table S3. Enriched GO terms based on the results of TG EWAS. Table S4. Enriched GO terms based on the Model 1 results of HDL EWAS. Table S5. KEGG enriched pathways based on the results of EWAS. Table S6. Reactome enriched pathways based on the results of EWAS. Table S8. Cross-lagged association between lipid measures and DNA methylation stratified by zygosity.
Biochemistry
Cell Biology
Genetics
Molecular Biology
Biological Sciences not elsewhere classified
Cancer
figshare
2022
2022-10-24
2024-02-23
Journal contribution
318296 Bytes
10.6084/m9.figshare.21385910
10.1186/s13148-022-01356-x
CC BY + CC0