10.6084/M9.FIGSHARE.21285810
Yongzhen Mo
Yongzhen
Mo
Central South University
Yumin Wang
Yumin
Wang
Xiangya Hospital Central South University
Yian Wang
Yian
Wang
Central South University
Xiangying Deng
Xiangying
Deng
Central South University
Qijia Yan
Qijia
Yan
Xiangya Hospital Central South University
Chunmei Fan
Chunmei
Fan
Central South University
Shuai Zhang
Shuai
Zhang
Xiangya Hospital Central South University
Shanshan Zhang
Shanshan
Zhang
Xiangya Hospital Central South University
Zhaojian Gong
Zhaojian
Gong
Second Xiangya Hospital of Central South University
Lei Shi
Lei
Shi
Second Xiangya Hospital of Central South University
Qianjin Liao
Qianjin
Liao
Central South University
Can Guo
Can
Guo
Central South University
Yong Li
Yong
Li
Baylor College of Medicine
Guiyuan Li
Guiyuan
Li
Central South University
Zhaoyang Zeng
Zhaoyang
Zeng
Central South University
Weihong Jiang
Weihong
Jiang
Xiangya Hospital Central South University
Wei Xiong
Wei
Xiong
Central South University
Bo Xiang
Bo
Xiang
Central South University
Additional file 11 of Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop
Additional file 11: Figure S2. circPVT1 promotes the migration and invasion of NPC in vitroand metastasis of NPCin vivo. A-B. The expression of circPVT1 were measured in CNE2 and 5-8F cells after transfection with the circPVT1 overexpression vector or circPVT1 siRNA. PVT1 expression was not affected in CNE2 and 5-8F cells after overexpresion or knockdown of circPVT. All experiments were repeated at least three times. Data were represented as mean ± SD. ***, p < 0.001; ns, not significant. C-D. Cell Counting Kit-8 and colony formation assays showed that circPVT1 had no effect on the growth and proliferation of NPC cells. Data were represented as mean ± SD. ns, not significant. E. H&E staining of lung metastatic tumor foci and representative images of circPVT1 expression as assessed by in situ hybridization (200×, scale bar, 50 μm). F. Images of footpad tumor formation in nude mice on day 21. Mice were injected with 1×106 CNE2 cells after overexpression or knockdown of circPVT1.G. Representative images of immunohistochemical staining for pan-cytokeratin in lymphatic tissues of mice. Scale bar, 50 μm.
Biophysics
Biochemistry
Cell Biology
Genetics
Molecular Biology
Physiology
Immunology
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Computational Biology
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2022
2022-10-06
2023-06-13
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10.1038/s41388-021-02079-8
10.1096/fj.202001508R
10.1002/1878-0261.12703
10.7150/jca.31345
10.1093/carcin/bgy143
10.7150/jca.30454
10.1096/fj.202000039RR
10.1007/s11427-017-9172-6
10.1186/s12943-017-0598-7
10.1016/j.canlet.2020.09.006
10.1016/j.canlet.2018.03.035
10.1186/s12943-018-0827-8
10.1007/s11427-021-2089-8
10.1007/s11427-021-2089-8
10.1038/s41388-020-01531-5
10.1080/15548627.2021.1917131
10.1016/j.aca.2021.339210
10.1158/0008-5472.CAN-20-4321
10.1186/s12943-021-01409-4
10.3389/fonc.2019.00609
10.1038/s41419-018-0265-y
10.1186/s12943-020-01237-y
10.1007/s00018-019-03222-1
10.1093/carcin/bgy108
10.1016/j.canlet.2016.12.006
10.1186/s13059-017-1368-y
10.1186/s13046-021-01964-0
10.1016/j.biopha.2020.109828
10.1016/S0960-9822%2899%2980091-8
10.18632/oncotarget.6155
10.1186/s13046-017-0614-1
10.1111/cas.14034
10.1186/s12943-020-1147-3
10.3389/fonc.2021.616202
10.1186/s12943-022-01502-2
10.1016/j.tibs.2021.11.004
10.1093/nar/gkw027
10.1038/cdd.2016.133
10.1126/sciadv.abb7426
10.1126/sciadv.abe5043
10.1038/s41416-021-01600-w
10.3389/fonc.2022.814504
10.1016/j.cell.2016.03.020
10.1186/s13046-021-01952-4
10.1038/s41467-022-28479-2
10.1158/0008-5472.CAN-17-3009
10.1016/j.cell.2015.02.014
10.1186/s12943-018-0911-0
10.1186/s12943-022-01659-w
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