10.6084/M9.FIGSHARE.20036644.V1
Tengcheng Que
Tengcheng
Que
Jing Li
Jing
Li
Yugan He
Yugan
He
Panyu Chen
Panyu
Chen
Wei Lin
Wei
Lin
Meihong He
Meihong
He
Lei Yu
Lei
Yu
Aiqiong Wu
Aiqiong
Wu
Luohao Tan
Luohao
Tan
Yingjiao Li
Yingjiao
Li
Yanling Hu
Yanling
Hu
Yigang Tong
Yigang
Tong
Human parainfluenza 3 and respiratory syncytial viruses detected in pangolins
<p>Pangolins have gained increasing global attention owing to their public health significance as potential zoonotic hosts since the identification of SARS-CoV-2-related viruses in them. Moreover, these animals could carry other respiratory viruses. In this study, we investigated the virome composition of 16 pangolins that died in 2018 with symptoms of pneumonia using metagenomic approaches. A total of eight whole virus sequences belonging to the <i>Paramyxoviridae</i> or <i>Pneumoviridae</i> families were identified, including one human parainfluenza virus 3, one human respiratory syncytial virus A, and six human respiratory syncytial virus B. All of these sequences showed more than 99% nucleotide identity with the virus isolated from humans at the whole-genome level and clustered with human viruses in the phylogenetic tree. Our findings provide evidence that pangolins are susceptible to HPIV3 and HRSV infection. Therefore, public awareness of the threat of pangolin-borne pathogens is essential to stop their human consumption and to prevent zoonotic viral transmission.</p>
Medicine
Microbiology
Genetics
Evolutionary Biology
Environmental Sciences not elsewhere classified
Ecology
Sociology
Immunology
Biological Sciences not elsewhere classified
Cancer
Science Policy
Mental Health
Infectious Diseases
Virology
Taylor & Francis
2022
2022-06-09
2024-02-09
Online resource
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10.6084/m9.figshare.20036644
10.1080/22221751.2022.2086071
CC BY 4.0