10.6084/M9.FIGSHARE.14815616.V1
Weiqing Jiang
Weiqing
Jiang
Tingting Wang
Tingting
Wang
Chen Liu
Chen
Liu
Mingzhu Deng
Mingzhu
Deng
Xiao Ren
Xiao
Ren
Fei Wang
Fei
Wang
Yaqing Zhang
Yaqing
Zhang
Xueying Yu
Xueying
Yu
Lingling Yao
Lingling
Yao
Yonggang Wang
Yonggang
Wang
A 16S rRNA gene sequencing based study of oral microbiota in migraine patients in China
<p>Migraine is a primary headache characterized by moderate or severe headache attacks, accompanied with reversible neurological and systemic symptoms. There are rare biomarkers for the disease. While emerging evidence has indicated the connection between gut microbiota and migraine, the relation between oral microbiota and migraine is barely known. Thus, the objective of the current study was to explore a possible correlation between oral microbiota and migraine. We compared the oral microbiota communities of migraine patients (26) with healthy subjects (29) via 16S rRNA gene sequencing. Alpha diversity indices were higher in migraine group compared with control group, whereas beta diversity indices also showed significant difference. A total of 23 genera were found differentially abundant between migraine and control groups. To conclude, there was a significant compositional difference in oral microbiota in migraine patients compared with healthy subjects.</p>
Microbiology
Cell Biology
Genetics
Neuroscience
Physiology
Chemical Sciences not elsewhere classified
Ecology
Biological Sciences not elsewhere classified
Science Policy
Taylor & Francis
2021
2021-06-21
2024-02-12
Journal contribution
369651 Bytes
10.6084/m9.figshare.14815616
10.1080/21655979.2021.1933840
CC BY 4.0