10.5518/915
Liao, Laura
Laura
Liao
https://orcid.org/0000-0001-6069-2633
Los Alamos National Laboratory
Carruthers, Jonathan
Jonathan
Carruthers
https://orcid.org/0000-0002-1372-3254
Smither, Sophie J.
Sophie J.
Smither
Defence Science and Technology Laboratory
CL4 Virology Team
Defence Science and Technology Laboratory
Weller, Simon A.
Simon A.
Weller
Defence Science and Technology Laboratory
Williamson, Diane
Diane
Williamson
Defence Science and Technology Laboratory
Laws, Thomas R.
Thomas R.
Laws
Defence Science and Technology Laboratory
Garcia-Dorival, Isabel
Isabel
Garcia-Dorival
University of Liverpool
Hiscox, Julian
Julian
Hiscox
University of Liverpool
Holder, Benjamin P.
Benjamin P.
Holder
Grand Valley State University
Beauchemin, Catherine
Catherine
Beauchemin
https://orcid.org/0000-0003-0599-0069
Ryerson University
RIKEN
Perelson, Alan S.
Alan S.
Perelson
Los Alamos National Laboratory
LOPEZ-GARCIA, MARTIN
MARTIN
LOPEZ-GARCIA
https://orcid.org/0000-0003-3833-8595
University of Leeds
Lythe, Grant
Grant
Lythe
https://orcid.org/0000-0001-7966-5571
University of Leeds
Barr, John
John
Barr
University of Leeds
molina-parís, carmen
carmen
molina-parís
https://orcid.org/0000-0001-9828-6737
University of Leeds
Dataset associated with 'Quantification of Ebola virus replication kinetics in vitro'
University of Leeds
2020
Dataset
FOS: Mathematics
Virology
en
10.1371/journal.pcbi.1008375
Open Government Licence v3.0
This dataset is associated with ‘Quantification of Ebola virus replication kinetics in vitro’. In the paper, a mathematical model is developed to describe the replication of Ebola virus in Vero cells. The model is parametrised using measurements of total and infectious extracellular virus at three different multiplicities of infection. The results provide insights into the distribution of time an infected cell spends in the eclipse phase (the period between infection and the start of virus production), as well as the rate at which infectious virions lose infectivity. Here, we provide all the experimental results necessary to parametrise the mathematical model.