10.5281/ZENODO.1342361
ПОМОГАЙБО Валентин Михайлович
0000-0002-9828-2565
БЕРЕЗАН Олексій Іванович
0000-0002-4959-3594
ПЕТРУШОВ Андрій Васильович
0000-0002-1269-2978
Генетика Специфічного Розладу Навчання
Zenodo
2018
specific learning disorder
reading
dyslexia
writing
dysgraphia
mathematic
dyscalculia
mathematics ability
candidate loci and genes
2018-08-09
uk
Journal article
https://zenodo.org/record/1342361
10.5281/zenodo.1342360
Creative Commons Attribution 4.0
Open Access
<p>Specific learning disorder is characterized by persistent and impairing<br>
difficulties with learning foundational academic skills in reading, writing, and/or<br>
math and is not associated with other psychiatric or neurological diseases. It may be<br>
complex and multifactorial, involving a combination of polygeneity and<br>
heterogeneity. There are better investigated genetic aspects of specific reading<br>
disability. In the human genome there were discovered at least 9 candidate loci and<br>
14 candidate genes with different significance levels. Genetic studies of specific<br>
writing disability were not accomplished. In the modern technological and<br>
computerized world there is valued mostly mathematical ability and so researchers<br>
are interested in the nature of math ability and math talent, but not of math<br>
disability. There were found two genes and a certain domain sequences, variants of<br>
which are associated with math abilities. Further molecular genetic researches of<br>
sufficiently large samples are necessary to understand the genetic nature of specific<br>
learning disorders.</p>