10.5061/DRYAD.V54P0
Pauliny, Angela
University of Gothenburg
Devlin, Robert H.
Fisheries and Oceans Canada
Johnsson, Jörgen I.
University of Gothenburg
Blomqvist, Donald
University of Gothenburg
Data from: Rapid growth accelerates telomere attrition in a transgenic fish
Dryad
dataset
2015
Transgenesis
Regeneration
Oncorhynchus kisutch
rapid growth
telomere attrition
life-history trade-off
2015-08-04T20:32:11Z
2015-08-04T20:32:11Z
en
https://doi.org/10.1186/s12862-015-0436-8
15933 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Background: Individuals rarely grow as fast as their physiologies permit
despite the fitness advantages of being large. One reason may be that
rapid growth is costly, resulting for example in somatic damage. The
chromosomal ends, the telomeres, are particularly vulnerable to such
damage, and telomere attrition thus influences the rate of ageing. Here,
we used a transgenic salmon model with an artificially increased growth
rate to test the hypothesis that rapid growth is traded off against the
ability to maintain somatic health, assessed as telomere attrition.
Results: We found substantial telomere attrition in transgenic fish, while
maternal half-sibs growing at a lower, wild-type rate seemed better able
to maintain the length of their telomeres during the same time period.
Conclusions: Our results are consistent with a trade-off between rapid
growth and somatic (telomere) maintenance in growth-manipulated fish.
Since telomere erosion reflects cellular ageing, our findings also support
theories of ageing postulating that unrepaired somatic damage is
associated with senescence.
Data on relative telomere length, weight, and body length for
GH-transgenic coho salmon and their wild-type maternal
half-sibsGH-transgenic coho salmon and their wild-type maternal half-sibs
were generated and sampled at Fisheries and Oceans Canada. Telomere
attrition rate was measured at University of Gothenburg, Sweden. The
variables included in the data sheet (Excel) are explained in detail as
comments in the respective column heading.Pauliny et
al_BMCEvolBiol_2015.xlsx
Canada
Sweden