10.5061/DRYAD.SF7M0CG4M
Lund, Andrea
0000-0003-0880-310X
Stanford University
Rehkopf, David
0000-0002-7597-6513
Stanford University School of Medicine
Sokolow, Susanne
Stanford University
Sam, M. Moustapha
Espoir pour la Sante
Jouanard, Nicolas
Espoir pour la Sante
Schacht, Anne-Marie
Espoir pour la Sante
Senghor, Simon
Espoir pour la Sante
Fall, Assane
Espoir pour la Sante
Riveau, Gilles
Espoir pour la Sante
De Leo, Giulio
Stanford University
Lopez-Carr, David
University of California, Santa Barbara
Land use impacts on parasitic infection: A cross-sectional epidemiological
study on the role of irrigated agriculture in schistosome infection in a
dammed landscape
Dryad
dataset
2020
National Science Foundation
https://ror.org/021nxhr62
1414102
Bill & Melinda Gates Foundation
https://ror.org/0456r8d26
OPP1114050
Fogarty International Center
https://ror.org/02xey9a22
R01TW010286
Stanford University
https://ror.org/00f54p054
James and Nancy Kelso Fellowship: Interdisciplinary Graduate Fellowship
Emmett Interdisciplinary Program in Environment and Resources*
Davis Family E-IPER Fellowship
Emmett Interdisciplinary Program in Environment and Resources
Davis Family E-IPER Fellowship
2021-03-22T00:00:00Z
2021-03-22T00:00:00Z
en
52736 bytes
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CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Background: Water resources development promotes agricultural expansion
and food security. But are these benefits offset by increased infectious
disease risk? Dam construction on the Senegal River in 1986 was followed
by agricultural expansion and increased transmission of human
schistosomes. Yet the mechanisms linking theseĀ processes at the
individual and household levels remain unclear. We investigated the
association between household land use and schistosome infection in
children. Methods: We analyzed cross-sectional household survey data (n =
655) collected in 16 rural villages in August 2016 across demographic,
socio-economic and land use dimensions, which were matched to S.
haematobium (n = 1232) and S. mansoni (n = 1222) infection data collected
from school-aged children. Mixed effects regression determined the
relationship between irrigated area and schistosome infection presence and
intensity. Results: Controlling for socio-economic and demographic risk
factors, irrigated area cultivated by a household was associated with an
increase in the presence of S. haematobium infection (odds ratio [OR] =
1.14; 95% confidence interval [95% CI]: 1.03, 1.28) but not S. mansoni
infection (OR = 1.02; 95% CI: 0.93, 1.11). Associations between infection
intensity and irrigated area were positive but imprecise (S. haematobium:
rate ratio [RR] = 1.05; 95% CI: 0.98, 1.13, S. mansoni: RR = 1.09; 95% CI:
0.89, 1.32). Conclusion: Household engagement in irrigated agriculture
increases individual risk of S. haematobium but not S. mansoni infection.
Increased contact with irrigated landscapes likely drives exposure, with
greater impacts on households relying on agricultural livelihoods.