10.5061/DRYAD.S4MW6M96M
Cheng, Luqi
0000-0002-4890-7424
University of Electronic Science and Technology of China
Zhang, Yuanchao
University of Electronic Science and Technology of China
Li, Gang
Chinese Academy of Sciences
Wang, Jiaojian
University of Electronic Science and Technology of China
Sherwood, Chet
George Washington University
Gong, Gaolang
Beijing Normal University
Fan, Linzhong
Chinese Academy of Sciences
Jiang, Tianzi
Chinese Academy of Sciences
Connectional asymmetry of the inferior parietal lobule shapes hemispheric
specialization in humans, chimpanzees, and rhesus macaques
Dryad
dataset
2021
Evolutionary Biology, Neuroscience
National Natural Science Foundation of China
https://ror.org/01h0zpd94
91432302
Guangdong Province Introduction of Innovative R&D Team
http://dx.doi.org/10.13039/100012540
2018B030333001
Youth Innovation Promotion Association
https://ror.org/031141b54
Peking University
https://ror.org/02v51f717
Beijing Municipal Science & Technology Commision
https://ror.org/034k14f91
Z161100000216139
Science Frontier Program of the Chinese Academy of Sciences
QYZDJ-SSW-SMC019
Guangdong Pearl River Talents Plan
2016ZT06S220
National Science Foundation
https://ror.org/021nxhr62
SMA-1542848
Strategic Priority Research Program of Chinese Academy of Sciences
XDB32030200
2021-06-28T00:00:00Z
2021-06-28T00:00:00Z
en
https://doi.org/10.7554/eLife.67600
3666224 bytes
7
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
The inferior parietal lobule (IPL) is one of the most expanded cortical
regions in humans relative to other primates. It is also among the most
structurally and functionally asymmetric regions in the human cerebral
cortex. Whether the structural and connectional asymmetries of IPL
subdivisions differ across primate species and how this relates to
functional asymmetries remain unclear. We identified IPL subregions that
exhibited positive allometric in both hemispheres, scaling across rhesus
macaque monkeys, chimpanzees, and humans. The patterns of IPL subregions
asymmetry were similar in chimpanzees and humans, but no IPL asymmetries
were evident in macaques. Among the comparative sample of primates, humans
showed the most widespread asymmetric connections in the frontal,
parietal, and temporal cortices, constituting leftward asymmetric networks
that may provide an anatomical basis for language and tool use. Unique
human asymmetric connectivity between the IPL and primary motor cortex
might be related to handedness. These findings suggest that structural and
connectional asymmetries may underlie hemispheric specialization of the
human brain.