10.5061/DRYAD.RR4XGXD8D
CLO, Josselin
Charles University
Opedal, Øystein
Lund University
Genetics of quantitative traits with dominance under stabilizing and
directional selection in partially selfing species
Dryad
dataset
2021
directional dominance
evolvability
Quantitative genetics
self-fertilization
standing genetic variation
2021-06-22T00:00:00Z
2021-06-22T00:00:00Z
en
218387 bytes
5
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Recurrent self-fertilization is thought to lead to reduced adaptive
potential by decreasing the genetic diversity of populations, thus leading
selfing lineages down an evolutionary ‘blind alley’. Though well supported
theoretically, empirical support for reduced adaptability in selfing
species is limited. One limitation of classical theoretical models is that
they assume pure additivity of the fitness-related traits that are under
stabilizing selection, despite ample evidence that quantitative traits are
subject to dominance. Here we relax this assumption and explore the effect
of dominance on a fitness-related trait under stabilizing selection for
populations that differ in selfing rates. By decomposing the genetic
variance into additional components specific to inbred populations, we
show that dominance components can explain a substantial part of the
genetic variance of inbred populations. We also show that ignoring these
components leads to an upward bias in the predicted response to selection.
Finally, we show that when considering the effect of dominance, the
short-term evolutionary potential of populations remains comparable across
the entire gradient in outcrossing rates, and genetic associations can
even make selfing populations more evolvable on the longer term,
reconciling theoretical and empirical results.