10.5061/DRYAD.RM266
Giménez, Mabel D.
University of York
White, Thomas A.
Cornell University
Hauffe, Heidi C.
University of York
Panithanarak, Thadsin
University of York
Searle, Jeremy B.
University of York
Data from: Understanding the basis of diminished gene flow between
hybridizing chromosome races of the house mouse
Dryad
dataset
2013
Chromosomal Evolution
2013-01-02T19:41:00Z
2013-01-02T19:41:00Z
en
https://doi.org/10.1111/evo.12054
178688 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Speciation may be promoted in hybrid zones if there is an interruption to
gene flow between the hybridizing forms. For hybridizing chromosome races
of the house mouse in Valtellina (Italy) distinguished by whole-arm
chromosomal rearrangements, previous studies have shown that there is
greater interruption to gene flow at the centromeres of chromosomes that
differ between the races than at distal regions of the same chromosome or
at the centromeres of other chromosomes. Here, by increasing the number of
markers along race-specific chromosomes, we reveal a decay in between-race
genetic differentiation from the centromere to the distal telomere. For
the first time, we use simulation models to investigate the possible role
of recombination suppression and hybrid breakdown in generating this
pattern. We also consider epistasis and selective sweeps as explanations
for isolated chromosomal regions away from the centromere showing
differentiation between the races. Hybrid breakdown alone is the simplest
explanation for the decay in genetic differentiation with distance from
the centromere. Robertsonian fusions/whole-arm reciprocal translocations
are common chromosomal rearrangements characterizing both closely related
species and races within species, and this fine-scale empirical analysis
suggests that the unfitness associated with these rearrangements in the
heterozygous state may contribute to the speciation process.
RAW_MICROSAT_DATA_FOR_DRYADMicrosatellite data for the loci and
populations described in the manuscript. Data are in CONVERT format, which
can easily be converted to many other formats using either the program
CONVERT or PGDSpider.