10.5061/DRYAD.RD70F
Evans, Teri
University of Nottingham
Wade, Christopher M.
University of Nottingham
Chapman, Frank A.
University of Florida
Johnson, Andrew D.
University of Nottingham
Loose, Matthew
University of Nottingham
Data from: Acquisition of germ plasm accelerates vertebrate evolution.
Dryad
dataset
2015
Preformation
Germ Plasm
Developmental Constraint
Phylogenetic Incongruence
Epigenesis
2015-04-09T00:00:00Z
2015-04-09T00:00:00Z
en
https://doi.org/10.1126/science.1249325
7524519828 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Primordial germ cell (PGC) specification occurs either by induction from
pluripotent cells (epigenesis) or by a cell-autonomous mechanism mediated
by germ plasm (preformation). Among vertebrates, epigenesis is basal,
whereas germ plasm has evolved convergently across lineages and is
associated with greater speciation. We compared protein-coding sequences
of vertebrate species that employ preformation with their sister taxa that
use epigenesis and demonstrate that genes evolve more rapidly in species
containing germ plasm. Furthermore, differences in rates of evolution
appear to cause phylogenetic incongruence in protein-coding sequence
comparisons between vertebrate taxa. Our results support the hypothesis
that germ plasm liberates constraints on somatic development and that
enhanced evolvability drives the evolution of germ plasm.
Scripts for AnalysesThis file contains the instructions for generating the
appropriate mySQL databases and the scripts required to process this data
and recreate the analyses described in Evans et al.Scripts.tar.gzAlignment
FilesThis file contains the folder system storing the alignments (*.nex)
and Maximum-Likelihood tree files (*_tree.tre) for the sequences presented
in Evans et al. Each file is named according to the seq_number information
as in the database basic_db.sql (also contained within this DataDryad
submission). Each alignment contains only the sequence from the first two
codon positions as reported in Evans et. al.Alignment_files.tar.gzmySQL
Database including dataThis file contains a mySQL database including all
the data used in Evans et al. It is in the same format as the database
which can be created using the files available in the Scripts package
associated with this datadryad package.basic_db.sql