10.5061/DRYAD.HK860
Sheppard, Samuel K.
University of Oxford
Swansea University
Cheng, Lu
University of Helsinki
Méric, Guillaume
Swansea University
de Haan, Caroline P. A.
University of Helsinki
Llarena, Ann-Katrin
University of Helsinki
Marttinen, Pekka
Aalto University
Vidal, Ana
University of Helsinki
Ridley, Anne
Wellcome Trust
Clifton-Hadley, Felicity
University of Oxford
Connor, Thomas R.
Cardiff University
Strachan, Norval J. C.
University of Aberdeen
Forbes, Ken
University of Aberdeen
Colles, Frances M.
University of Oxford
Jolley, Keith A.
University of Oxford
Bentley, Stephen D.
Wellcome Trust
Maiden, Martin C. J.
University of Oxford
Hänninen, Marja-Liisa
University of Helsinki
Parkhill, Julian
Wellcome Trust
Hanage, William P.
Harvard University
Corander, Jukka
University of Helsinki
Data from: Cryptic ecology among host generalist Campylobacter jejuni in
domestic animals
Dryad
dataset
2014
Microbial Biology
Coevolution
Campylobacter
2014-03-28T17:54:24Z
2014-03-28T17:54:24Z
en
https://doi.org/10.1111/mec.12742
66032921 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Homologous recombination between bacterial strains is theoretically
capable of preventing the separation of daughter clusters, and producing
cohesive clouds of genotypes in sequence space. However, numerous barriers
to recombination are known. Barriers may be essential such as adaptive
incompatibility, or ecological, which is associated with the opportunities
for recombination in the natural habitat. Campylobacter jejuni is a gut
colonizer of numerous animal species and a major human enteric pathogen.
We demonstrate that the two major generalist lineages of C. jejuni do not
show evidence of recombination with each other in nature, despite having a
high degree of host niche overlap and recombining extensively with
specialist lineages. However, transformation experiments show that the
generalist lineages readily recombine with one another in vitro. This
suggests ecological rather than essential barriers to recombination,
caused by a cryptic niche structure within the hosts.
Assembled 128 Campylobacter whole genome sequences128 Campylobacter whole
genomes sequenced using a Illumina HiSeq 2000 and assembled using Velvet.
Filenames refer to IDs in Table S1 in the associated
publication.MolEcol2014.zipComplete set of available STs for C. jejuni
(sequences)Sequences of every alleles for MLST profiles of 3,834 STs
present in the pubMLST Campylobacter database as of the 26th of May 2011
and used in the associated
publication.Complete_set_of_available_STs_for_Cjejuni_(sequences).xlsComplete host associations with C. jejuni ST clonal complexesComplete host associations with C. jejuni ST clonal complexes, using data extracted from pubMLST as of 26th May 2011, used in the associated publication to produce Fig. 1B.Complete_host_associations_with_ST_clonal_complexes_(pubMLST).xlsx