10.5061/DRYAD.H9942
Sun, Jin
The Hong Kong University of Science and Technology
Zhang, Yu
Research Center for Eco-Environmental Sciences
Xu, Ting
Hong Kong Baptist University
Zhang, Yang
South China Sea Institute Of Oceanology
Mu, Huawei
Hong Kong Baptist University
Zhang, Yanjie
Lan, Yi
The Hong Kong University of Science and Technology
Fields, Christopher J.
University of Illinois at Urbana Champaign
Hui, Jerome H. L.
Chinese University of Hong Kong
Zhang, Wei-Peng
The Hong Kong University of Science and Technology
Li, Runsheng
Hong Kong Baptist University
Nong, Wenyan
Chinese University of Hong Kong
Cheung, Fiona K. M.
Chinese University of Hong Kong
Qiu, Jian-Wen
Hong Kong Baptist University
Qian, Pei-Yuan
The Hong Kong University of Science and Technology
Data from: Adaptation to deep-sea chemosynthetic environments as revealed
by mussel genomes
Dryad
dataset
2017
chemosynthesis
Bathymodiolus platifrons
Bathymodiolus
mussel
Modiolus
Modiolus philippinarum
2017-04-04T19:16:48Z
2017-04-04T19:16:48Z
en
https://doi.org/10.1038/s41559-017-0121
1285813000 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Hydrothermal vents and methane seeps are extreme deep-sea ecosystems that
support dense populations of specialised macrobenthos such as mussels. But
lack of genome information hinders understanding of the adaptation of
these animals to such inhospitable environment. Here we report the genomes
of a deep-sea vent/seep mussel Bathymodiolus platifrons and a
shallow-water mussel Modiolus philippinarum. Phylogenetic analysis shows
that these mussel species diverged approximately 110.4 million years ago.
Many gene families, especially those for stabilising protein structures
and removing toxic substances from the cells, are greatly expanded in B.
platifrons, indicating adaptation to extreme environmental conditions. The
B. platifrons innate immune system is considerably more complex than that
of other lophotrochozoan species including M. philippinarum, with
significant expansion and high expression of gene families related to
immune recognition, endocytosis and caspase-mediated apoptosis in the
gill, revealing presumed genetic adaptation of the deep-sea mussel to the
presence of its chemoautotrophic endosymbionts. A follow-up metaproteomic
analysis of the gill of B. platifrons found methanotrophy, assimilatory
sulfate reduction, and ammonia metabolic pathways in the symbionts,
providing energy and nutrients to allow the host to thrive. Our study of
the genomic composition allowing symbiosis in extremophile molluscs gives
wider insights into the mechanisms of symbiosis in other organisms such as
deep-sea tubeworms and giant clams.
The assembled genomic scaffolds of Bathymodiolus platifronsBpl_v1.0.zipThe
assembled genomic scaffolds of Modiolus
philippinarumMph_v1.0.zipBathymodiolus platifrons genome annotation file
(gff3 format)Bpl_maker_v1.0.zipModiolus philippinarum genome annotation
file (gff3 format)Mph_maker_v1.0.zipThe predicted transcript sequences of
the MAKER v3.0 annotations for the genome of Bathymodiolus platifrons
(fasta format)Bpl.maker_FilteredModels_transcripts_v1.0.zipThe predicted
protein sequences of the MAKER v3.0 annotations for the genome of
Bathymodiolus platifrons (fasta
format)Bpl.maker_FilteredModels_proteins_v1.0.zipThe predicted transcript
sequences of the MAKER v3.0 annotations for the genome of Modiolus
philippinarum (fasta
format)Mph.maker_FilteredModels_transcripts_v1.0.zipThe predicted protein
sequences of the MAKER v3.0 annotations for the genome of Modiolus
philippinarum (fasta format)Mph.maker_FilteredModels_proteins_v1.0.zipThe
functional annotation and gene expression level file of the predicted
Bathymodiolus platifrons gene modelsAbbreviations used in this excel
table: tpm, Transcripts Per Kilobase Million; AM, adductor muscle; F,
foot; O, ovary; G, gill; M, mantle; and VM, visceral
mass.Bathymodiolus_FunAnno_FilteredGeneModels.xlsxThe functional
annotation and gene expression level file of the predicted Modiolus
philippinarum gene modelsAbbreviations used in this excel table: tpm,
Transcripts Per Kilobase Million; AM, adductor muscle; F, foot; G, gill;
M, mantle; and VM, visceral mass.Modiolus_FunAnno_FilteredGeneModels.xlsx