10.5061/DRYAD.D51C59ZZW
Van Cleve, Jeremy
0000-0003-3656-4257
University of Kentucky
Dunoyer, Luc
0000-0001-6573-3844
Wake Technical Community College
Seifert, Ashley
University of Kentucky
Ancestral state reconstruction for regeneration and autotomy in arthopods
and reptiles
Dryad
dataset
2020
National Science Foundation
https://ror.org/021nxhr62
1353713
National Science Foundation
https://ror.org/021nxhr62
1846260
National Institute of Arthritis and Musculoskeletal and Skin Diseases
https://ror.org/006zn3t30
R01AR070313
2020-06-19T00:00:00Z
2020-06-19T00:00:00Z
en
https://doi.org/10.1002/jez.b.22974
161797 bytes
6
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Some form of regeneration occurs in all lifeforms and extends from
single-cell organisms to humans. The degree to which regenerative ability
is distributed across different taxa, however, is harder to ascertain
given the potential for phylogenetic constraint or inertia, and adaptive
processes to shape this pattern. Here, we examine the phylogenetic history
of regeneration in two groups where the trait has been well-studied:
arthropods and reptiles. Because autotomy is often present alongside
regeneration in these groups, we performed ancestral state reconstructions
for both traits to more precisely assess the timing of their origins and
the degree to which these traits coevolve. Using an ancestral trait
reconstruction, we find that autotomy and regeneration were present at the
base of the arthropod and reptile trees. We also find that when autotomy
is lost it does not re-evolve easily. Lastly, we find that the
distribution of regeneration is intimately connected to autotomy with the
association being stronger in reptiles than in arthropods. While these
patterns suggest that decoupling autotomy and regeneration at a broad
phylogenetic scale may be difficult, the available data provides useful
insight into their entanglement. Ultimately, our reconstructions provide
important groundwork to explore how selection may have played a role
during the loss of regeneration in specific lineages.
Please see manuscript.