10.5061/DRYAD.CS604
Pedersen, Mads Lund
University of Oslo
Oslo University Hospital
Endestad, Tor
University of Oslo
Biele, Guido
University of Oslo
Norwegian Institute of Public Health
Data from: Evidence accumulation and choice maintenance are dissociated in
human perceptual decision making
Dryad
dataset
2016
2016-10-07T00:00:00Z
2016-10-07T00:00:00Z
en
https://doi.org/10.1371/journal.pone.0140361
5879250422 bytes
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CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Perceptual decision making in monkeys relies on decision neurons, which
accumulate evidence and maintain choices until a response is given. In
humans, several brain regions have been proposed to accumulate evidence,
but it is unknown if these regions also maintain choices. To test if
accumulator regions in humans also maintain decisions we compared delayed
and self-paced responses during a face/house discrimination decision
making task. Computational modeling and fMRI results revealed dissociated
processes of evidence accumulation and decision maintenance, with
potential accumulator activations found in the dorsomedial prefrontal
cortex, right inferior frontal gyrus and bilateral insula. Potential
maintenance activation spanned the frontal pole, temporal gyri, precuneus
and the lateral occipital and frontal orbital cortices. Results of a
quantitative reverse inference meta-analysis performed to differentiate
the functions associated with the identified regions did not narrow down
potential accumulation regions, but suggested that response-maintenance
might rely on a verbalization of the response.
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