10.5061/DRYAD.9KH1B
Llopart, Ana
University of Iowa
Herrig, Danielle
University of Iowa
Brud, Evgeny
University of Iowa
Stecklein, Zachary
University of Iowa
Data from: Sequential adaptive introgression of the mitochondrial genome
in Drosophila yakuba and D. santomea
Dryad
dataset
2014
recurrent adaptation
positive selection
2014-01-22T18:36:57Z
2014-01-22T18:36:57Z
en
https://doi.org/10.1111/mec.12678
2967887 bytes
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CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Interspecific hybridization provides the unique opportunity for species to
tap into genetic variation present in a closely related species and
potentially take advantage of beneficial alleles. It has become
increasingly clear that when hybridization occurs, mitochondrial DNA
(mtDNA) often crosses species boundaries, raising the possibility that it
could serve as a recurrent target of natural selection and source of
species’ adaptations. Here we report the sequences of 46 complete
mitochondrial genomes of Drosophila yakuba and D. santomea, two sister
species known to produce hybrids in nature (~3%). At least two independent
events of mtDNA introgression were uncovered in this study, including an
early invasion of the D. yakuba mitochondrial genome that fully replaced
the D. santomea mtDNA native haplotypes and a more recent, ongoing event
centered in the hybrid zone. Interestingly, this recent introgression
event bears the signature of Darwinian natural selection and the selective
haplotype can be found at low frequency in Africa mainland populations of
D. yakuba. We put forward the possibility that, because the effective
population size of D. santomea is smaller than that of D. yakuba, the
faster accumulation of mildly deleterious mutations associated with
Muller’s ratchet in the former species may have facilitated the
replacement of the mutationally loaded mitochondrial genome of D. santomea
by that of D. yakuba.
IMa2 input file (2 populations, mtDNA)Input file used in the simulations
of the Isolation-with-Migration (IM) model with 2 populations (D. yakuba
and D. santomea) performed with the program IMa2 and the dataset of
complete mitochondrial DNA sequencesLlopart_et_al_IMa2_2_pop.txtIMa2 input
file (3 populations, mtDNA)Input file used in the simulations of the
Isolation-with-Migration (IM) model with 3 populations (D. yakuba
mainland, D. yakuba island and D. santomea) performed with the program
IMa2 and the dataset of complete mitochondrial DNA
sequencesLlopart_et_al_IMa2_3_pop.txtIMa2 input file (2 populations, mtDNA
and Y chromosome)Input file used in the simulations of the
Isolation-with-Migration (IM) model with 2 populations (D. yakuba and D.
santomea) performed with the program IMa2 and the dataset of complete
mitochondrial and partial Y chromosome DNA
sequencesLlopart_et_al_IMa2_with_Y.txtGene tree fileInput file in MEGA
format used to obtain the gene tree shown in Fig. 3Llopart_et_al_Tree.meg