10.5061/DRYAD.8JV30
Pinharanda, Ana
University of Cambridge
Martin, Simon H.
University of Cambridge
Barker, Sarah L.
University of Cambridge
Davey, John W.
University of Cambridge
Jiggins, Chris D.
University of Cambridge
Data from: The comparative landscape of duplications in Heliconius
melpomene and Heliconius cydno
Dryad
dataset
2016
Heliconius
duplication
National Science Foundation
https://ror.org/021nxhr62
NERC NE/L501578/1
2016-09-23T13:49:24Z
2016-09-23T13:49:24Z
en
https://doi.org/10.1038/hdy.2016.107
594929 bytes
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CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Gene duplications can facilitate adaptation and may lead to
inter-population divergence, causing reproductive isolation. We used
whole-genome re-sequencing data from 34 butterflies to detect duplications
in two Heliconius species, H. cydno and H. melpomene. Taking advantage of
three distinctive signals of duplication in short-read sequencing data, we
identified 744 duplicated loci in H. cydno and H. melpomene, 96% of which
were validated with single molecule sequencing. We have found that
duplications overlap genes significantly less than expected at random in
H. melpomene, consistent with the action of background selection against
duplicates in functional regions of the genome. Duplicate loci that are
highly differentiated between H. melpomene and H. cydno map to four
different chromosomes. Four duplications were identified with a strong
signal of divergent selection, including an odorant binding protein and
another in close proximity with a known wing colour pattern locus that
differs between the two species.
merge_within_each_toolMerge within each tool: delly, cnvnator,
pindelmerged_by_tool_trio_cydnochromosome 2 duplication calls merged by
tool for the H. cydno (trio)merged_by_tool_trio_melpomenechromosome 2
merged by tool on the trio H. melpomene
samplesheliconius_set.vcfHeliconius set from population data (H. cydno +
H. melpomene)discovery_set_cydnoH. cydno discovery setdiscovery_set_melpH.
melpomene discovery set
Central America