10.5061/DRYAD.8081
Rebbeck, Clare A.
Imperial College London
Leroi, Armand M.
Imperial College London
Burt, Austin
Imperial College London
Data from: Mitochondrial capture by a transmissible cancer
Dryad
dataset
2010
Canis lupus familiaris
Canis latrans
Canis lupus
Canine transmissible cancer
2010-12-14T15:59:11Z
2010-12-14T15:59:11Z
en
https://doi.org/10.1126/science.1197696
140006 bytes
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CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Canine transmissible venereal tumor (CTVT) is an infectious cell line
circulating in many feral dog populations. It originated once, about
10,000 years ago. Phylogenetic analyses of mitochondrial sequences from
dogs, wolves, and a geographically diverse collection of CTVT samples
indicate that the cancer has periodically acquired mitochondria from its
host. We suggest that this may be because the cancer’s own mitochondria
have a tendency to degenerate, due to high mutation rates and relaxed
selection, resulting in host mitochondria being more fit.
Rebbeck phylogenyNexus file for phylogenetic tree of mitochondrial
sequence data. Data collected from canine transmissible venereal tumor and
host dog aligned with dog, wolf and coyote sequences.
Greece
Mexico
South Africa
Malaysia
Israel
Thailand
Kenya