10.5061/DRYAD.7V387
Anderson, Maria
Karolinska Institute
Grindefjord, Margaret
Karolinska Institute
Dahllöf, Göran
Karolinska Institute
Dahlén, Gunnar
University of Gothenburg
Twetman, Svante
University of Copenhagen
Data from: Oral microflora in preschool children attending a fluoride
varnish program: a cross-sectional study
Dryad
dataset
2017
preschool children
community health program
fluoride varnish
caries prevention
2013-2014
2017-11-29T00:00:00Z
2017-11-29T00:00:00Z
en
https://doi.org/10.1186/s12903-016-0325-6
227827 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
Background: To compare the oral microflora in preschool children attending
a fluoride varnish program with a reference group receiving a standard
oral health program without fluoride varnish applications. A second aim
was to relate the microbial composition to the caries prevalence. Methods:
Five hundred seven 3-year-old children were enrolled from a cohort of 3403
preschool children taking part in a community based oral health project.
Two hundred sixty-three of them had attended caries-preventive program
with semi-annual applications of a fluoride varnish since the age of 1
year (test group) while 237 had received standard preventive care
(reference group). Oral samples were collected with a sterile swab and
analysed with checkerboard DNA-DNA hybridization using 12 pre-determined
bacterial probes. Caries and background data were collected from clinical
examinations and questionnaires. Results: Gram-positive streptococci (S.
intermedius, S. salivarius, S. oralis) were most frequently detected and
displayed the highest counts in both groups. There were no significant
differences between the groups concerning prevalence of any of the
selected bacterial strains except for S. oralis that occurred less
frequently in the reference group. In children with caries, V. parvula
were significantly more common (p < 0.05) while strains of
Lactobacillus, Bifidobacterium and Neisseria were more prevalent among the
caries-free children (p < 0.05). Conclusions: A 2-year community
program with semi-annual fluoride varnish applications did not seem to
significantly influence the oral microflora in preschool children. Trial
registration: www.controlled-trials.com (ISRCTN35086887) 20131216
‘retrospectively registered’.
ReadMefileThis read me file describes the data file and supplementary file
accompanying the above publication and contact for correspondence1)
2016-11-26 Data set of the trialThe submitted file include data from the
Stop Caries Stockholm study. The database contains data on data caries,
oral microorganisms and patient background factors2) 2016-11-26 List of
the variables in the supplementary dataset used in the trial and
explanation of the codingList of the variables in the supplementary
dataset used in the trial and explanation of the coding
Sweden