10.5061/DRYAD.5037S
Matute, Daniel R.
University of Chicago
Gavin-Smyth, Jackie
University of Chicago
Liu, Geoffrey
University of Chicago
Data from: Variable post-zygotic isolation in Drosophila melanogaster/D.
simulans hybrids
Dryad
dataset
2014
2014-05-28T21:13:00Z
2014-05-28T21:13:00Z
en
https://doi.org/10.1111/jeb.12422
74995 bytes
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CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
The study of hybrid inviability reveals cryptic divergence between the
genetic interactions that maintain stable phenotypes in the pure species.
We characterized the effects of natural variation on the penetrance of
hybrid inviability phenotypes in crosses between Drosophila melanogaster
and two species of the D. simulans subcomplex, D. simulans and D.
sechellia. Using a panel of wild-caught lines, we studied the levels of
genetic variance present in D. simulans and D. sechellia affecting
prezygotic and post-zygotic isolation in hybridizations with D.
melanogaster females. We observed extensive variability in the viability
of hybrid individuals, dependent on the genotype of the parents,
suggesting that intraspecific natural variation manifests directly in
hybrid phenotypes. Furthermore, we found that genetic background
significantly affects the penetrance of a well-studied determinant of
hybrid inviability: the interaction between Hmrmel–Lhrsim. Our results
suggest that hybrid inviability – and reproductive isolation generally –
can be modified by polymorphisms at multiple loci segregating within the
parental species. Just as the penetrance of most mutant phenotypes can be
modified by the genetic background within the pure species, the penetrance
of hybrid inviability phenotypes is highly influenced by the parental
genotypes.
Matute_etal_JEB_ReadMeDRM_JGS_GL_raw_data.zip