10.5061/DRYAD.3B426
Haber, Annat
Michigan State University
Tel Aviv University
Dworkin, Ian
Michigan State University
McMaster University
Data from: Disintegrating the fly: a mutational perspective on phenotypic
integration and covariation
Dryad
dataset
2016
Mutations
phenotypic covariation
integrartion
2016-10-12T14:36:50Z
2016-10-12T14:36:50Z
en
https://doi.org/10.1111/evo.13100
6109944 bytes
1
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication
The structure of environmentally induced phenotypic covariation can
influence the effective strength and magnitude of natural selection. Yet
our understanding of the factors that contribute to and influence the
evolutionary lability of such covariation is poor. Most studies have
either examined environmental variation without accounting for
covariation, or examined phenotypic and genetic covariation without
distinguishing the environmental component. In this study we examined the
effect of mutational perturbations on different properties of
environmental covariation, as well as mean shape. We use strains of
Drosophila melanogaster bearing well-characterized mutations known to
influence wing shape, as well as naturally-derived strains, all reared
under carefully-controlled conditions and with the same genetic
background. We find that mean shape changes more freely than the
covariance structure, and that different properties of the covariance
matrix change independently from each other. The perturbations affect
matrix orientation more than they affect matrix eccentricity or total
variance. Yet, mutational effects on matrix orientation do not cluster
according to the developmental pathway that they target. These results
suggest that it might be useful to consider a more general concept of
‘decanalization’, involving all aspects of variation and covariation.
Data and R codeRaw data, R code, and other information required to
reproduce the analyses, figures, and tables in Haber and Dworkin 2016:
"Dis-integrating the fly: A mutational perspective on phenotypic
integration and covariation."intMutant_FruitFly_Evolution2016.zip
North America