10.25776/63AV-ZC24
Wu, Erika
Erika
Wu
Statistical Genetic Discoveries Using Restricted Maximum Likelihood Method
Old Dominion University Libraries
2022
Paper
In statistical genetics, genetic association and genomic prediction become more successful with a highly heritable trait. Identifying highly heritable components of a complex disease can thus advance scientific understanding of the disease and potentially lead to effective prevention and treatments. Using Matlab and existing large-scale genome datasets, we evaluate a restricted maximum likelihood approach to identify highly heritable components of a complex disease as a function of multiple clinical variables.