10.25504/FAIRSHARING.JWRA3E
FAIRsharing Team
FAIRsharing record for: MobiDB
MobiDB
FAIRsharing
2015
Life Science
Intrinsically disordered proteins
Curated information
Protein
Structure
This FAIRsharing record describes: A database of protein disorder and mobility annotations. MobiDB was designed to offer a centralized resource for annotations of intrinsic protein disorder. The database features three levels of annotation: manually curated, indirect and predicted. Manually curated data is extracted from the DisProt database. Indirect data is inferred from PDB structures that are considered an indication of intrinsic disorder. The 10 predictors currently included (three ESpritz flavors, two IUPred flavors, two DisEMBL flavors, GlobPlot, VSL2b and JRONN) enable MobiDB to provide disorder annotations for every protein in absence of more reliable data. The new version also features a consensus annotation and classification for long disordered regions. In order to complement the disorder annotations, MobiDB features additional annotations from external sources. Annotations from the UniProt database include post-translational modifications and linear motifs. Pfam annotations are displayed in graphical form and are link-enabled, allowing the user to visit the corresponding Pfam page for further information. Experimental protein?protein interactions are also classified for disorder content.
The source of this description is the metadata record on FAIRsharing.org, an educational and informative resource that describes and links databases, standards, and data policies. FAIRsharing also creates collections of these resources and recommendations of databases and standards based on 3rd party data policies.