10.25402/NNM.21908376.V1
Yu-Ting Bai
Yu-Ting
Bai
Xue-Qiong Zhang
Xue-Qiong
Zhang
Xiao-Jie Chen
Xiao-Jie
Chen
Gang Zhou
Gang
Zhou
Augusta University
Biomarker Technologies (China)
Novogene Bioinformatics Institute
Nanomedicines in oral cancer: inspiration comes from extracellular vesicles and biomimetic nanoparticles
<p>Oral cancer is a common life-threatening malignancy having high mortality and morbidity rates. During</p>
<p>the treatment process, individuals unavoidably experience severe side effects. It is essential to develop</p>
<p>safer and more effective strategies. Currently, extracellular vesicles (EVs) and biomimetic nanoparticles are</p>
<p>nanomedicines with long-term blood circulation and lower off-target toxicity that orchestrate immune</p>
<p>responses and accumulate specifically in tumor sites. EVs create a synergetic effect by encapsulating</p>
<p>drugs and collaborating with naturally loaded elements in the EVs. Biomimetic nanoparticles retain the</p>
<p>characteristic features of the synthetic nanocarriers and inherit the intrinsic cellmembrane functionalities.</p>
<p>This review outlines the properties, applications, challenges, pros and cons of EVs and biomimetic</p>
<p>nanoparticles, providing novel perspectives on oral cancer.</p>
Nanomedicine
Future Science Group
2023
2023-01-17
2023-01-17
Dataset
2676573 Bytes
10.2217/nnm-2022-0142
10.25402/NNM.21908376
CC BY 4.0