{
"id": "https://doi.org/10.7490/f1000research.1116819.1",
"doi": "10.7490/F1000RESEARCH.1116819.1",
"url": "https://f1000research.com/posters/8-773",
"types": {
"ris": "GEN",
"bibtex": "misc",
"citeproc": "article",
"schemaOrg": "CreativeWork",
"resourceTypeGeneral": "Other"
},
"creators": [
{
"name": "Andrén, Per",
"nameType": "Personal",
"givenName": "Per",
"familyName": "Andrén",
"affiliation": []
},
{
"name": "Cruz, Lorena Fernández De La",
"nameType": "Personal",
"givenName": "Lorena Fernández De La",
"familyName": "Cruz",
"affiliation": []
},
{
"name": "Lenhard, Fabian",
"nameType": "Personal",
"givenName": "Fabian",
"familyName": "Lenhard",
"affiliation": []
},
{
"name": "Isomura, Kayoko",
"nameType": "Personal",
"givenName": "Kayoko",
"familyName": "Isomura",
"affiliation": []
},
{
"name": "Andersson, Erik",
"nameType": "Personal",
"givenName": "Erik",
"familyName": "Andersson",
"affiliation": []
},
{
"name": "Hall, Charlotte L.",
"nameType": "Personal",
"givenName": "Charlotte L.",
"familyName": "Hall",
"affiliation": []
},
{
"name": "E. Bethan Davies",
"affiliation": []
},
{
"name": "Murphy, Tara",
"nameType": "Personal",
"givenName": "Tara",
"familyName": "Murphy",
"affiliation": []
},
{
"name": "Hollis, Chris",
"nameType": "Personal",
"givenName": "Chris",
"familyName": "Hollis",
"affiliation": []
},
{
"name": "Feldman, Inna",
"nameType": "Personal",
"givenName": "Inna",
"familyName": "Feldman",
"affiliation": []
},
{
"name": "Bottai, Matteo",
"nameType": "Personal",
"givenName": "Matteo",
"familyName": "Bottai",
"affiliation": []
},
{
"name": "Serlachius, Eva",
"nameType": "Personal",
"givenName": "Eva",
"familyName": "Serlachius",
"affiliation": []
},
{
"name": "Mataix-Cols, David",
"nameType": "Personal",
"givenName": "David",
"familyName": "Mataix-Cols",
"affiliation": []
}
],
"titles": [
{
"title": "Clinical and cost–effectiveness of internet–delivered behaviour therapy for children and adolescents with Tourette syndrome: Protocol for a single-blind randomised controlled trial in Sweden"
}
],
"publisher": {
"name": "F1000 Research Limited"
},
"container": {},
"subjects": [],
"contributors": [],
"dates": [
{
"date": "2019",
"dateType": "Issued"
}
],
"publicationYear": 2019,
"identifiers": [],
"descriptions": [
{
"description": "Background:
Behaviour therapy (BT) for Tourette syndrome (TS) and chronic tic disorder (CTD) is effective but rarely available. To increase its availability, we developed a therapist- and parent-guided Internet-delivered BT programme for young people with TS/CTD, named BIP TIC. Preliminary results from a pilot study suggest that BIP TIC is a feasible and highly acceptable treatment. We now plan to evaluate BIP TIC in a full-scale randomised controlled trial in Sweden to determine its clinical efficacy, long-term durability, and cost-effectiveness. This poster outlines the trial protocol.
Methods:
We plan to conduct a single-blind parallel-group randomised controlled superiority trial, where participants (N=220) are randomised to either 10 weeks of BIP TIC (therapist- and parent-guided Internet-delivered exposure and response prevention) or a control condition (therapist- and parent-guided Internet-delivered education on tics). The trial will be coordinated at a single site in Stockholm, Sweden, but will recruit nationally. Eligibility criteria will include a diagnosis of TS/CTD, age between 9 and 17 years, and stable medication for tics, if on medication. Participants are assessed at post-treatment and at 3, 6, and 12 months follow-up. The primary outcome will be tic severity as measured by the Total Tic Severity Score of the Yale Global Tic Severity Scale at the 3-month follow-up, which will be assessed by raters blind to the treatment condition. A full health economic evaluation will be conducted. Data will be analysed using a pre-specified intention-to-treat statistical analysis plan.
Results and Conclusions:
Recruitment started in April 2019. If BIP TIC is superior to tic education alone, as well as cost-effective, we will aim to implement it in routine clinical care in Sweden.",
"descriptionType": "Other"
}
],
"providerId": "zwfe",
"clientId": "bl.f1000r",
"agency": "datacite",
"state": "findable"
}