{
"id": "https://doi.org/10.6084/m9.figshare.21211351",
"doi": "10.6084/M9.FIGSHARE.21211351",
"url": "https://tandf.figshare.com/articles/dataset/Platelet_Lymphocyte_Ratio_Neutrophil_Lymphocyte_Ratio_and_Their_Dynamic_Changes_with_Type_2_Diabetes_Mellitus_A_Cohort_Study_in_China/21211351",
"types": {
"ris": "DATA",
"bibtex": "misc",
"citeproc": "dataset",
"schemaOrg": "Dataset",
"resourceType": "Dataset",
"resourceTypeGeneral": "Dataset"
},
"creators": [
{
"name": "Zhang, Canjia",
"givenName": "Canjia",
"familyName": "Zhang"
},
{
"name": "Chen, Huan",
"givenName": "Huan",
"familyName": "Chen"
},
{
"name": "Cui, Shangxin",
"givenName": "Shangxin",
"familyName": "Cui"
},
{
"name": "Lin, Yeli",
"givenName": "Yeli",
"familyName": "Lin"
},
{
"name": "Liang, Yongqiang",
"givenName": "Yongqiang",
"familyName": "Liang"
},
{
"name": "Zhao, Ping",
"givenName": "Ping",
"familyName": "Zhao"
},
{
"name": "Wang, Changyi",
"givenName": "Changyi",
"familyName": "Wang"
},
{
"name": "Xu, Shan",
"givenName": "Shan",
"familyName": "Xu"
},
{
"name": "Peng, Xiaolin",
"givenName": "Xiaolin",
"familyName": "Peng"
},
{
"name": "Chen, Hongen",
"givenName": "Hongen",
"familyName": "Chen"
},
{
"name": "Wang, Li",
"givenName": "Li",
"familyName": "Wang"
},
{
"name": "Zhao, Dan",
"givenName": "Dan",
"familyName": "Zhao"
},
{
"name": "Zhang, Ming",
"givenName": "Ming",
"familyName": "Zhang"
},
{
"name": "Hu, Dongsheng",
"givenName": "Dongsheng",
"familyName": "Hu"
},
{
"name": "Lou, Yanmei",
"givenName": "Yanmei",
"familyName": "Lou"
},
{
"name": "Hu, Fulan",
"givenName": "Fulan",
"familyName": "Hu"
}
],
"titles": [
{
"title": "Platelet–Lymphocyte Ratio, Neutrophil–Lymphocyte Ratio and Their Dynamic Changes with Type 2 Diabetes Mellitus: A Cohort Study in China"
}
],
"publisher": {
"name": "Taylor & Francis"
},
"container": {},
"subjects": [
{
"subject": "Medicine"
},
{
"subject": "Biotechnology"
},
{
"subject": "Chemical Sciences not elsewhere classified"
},
{
"subject": "Immunology"
},
{
"subject": "FOS: Clinical medicine",
"schemeUri": "http://www.oecd.org/science/inno/38235147.pdf",
"subjectScheme": "Fields of Science and Technology (FOS)"
},
{
"subject": "Biological Sciences not elsewhere classified"
},
{
"subject": "Science Policy"
}
],
"contributors": [],
"dates": [
{
"date": "2022-09-27",
"dateType": "Created"
},
{
"date": "2023-05-30",
"dateType": "Updated"
},
{
"date": "2022",
"dateType": "Issued"
}
],
"publicationYear": 2022,
"identifiers": [],
"sizes": [
"21849180 Bytes"
],
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"rightsList": [
{
"rights": "Creative Commons Attribution 4.0 International",
"rightsUri": "https://creativecommons.org/licenses/by/4.0/legalcode",
"schemeUri": "https://spdx.org/licenses/",
"rightsIdentifier": "cc-by-4.0",
"rightsIdentifierScheme": "SPDX"
}
],
"descriptions": [
{
"description": "This study aimed at investigating the relationships between Platelet-Lymphocyte ratio (PLR) and Neutrophil–Lymphocyte ratio (NLR) and their dynamic changes (∆PLR, ∆NLR) with type 2 diabetes mellitus (T2DM) in a Chinese cohort study. This study recruited 41,439 individuals who were diagnosed without T2DM at first health examination and completed at least one follow-up. The relationships between NLR, PLR, ∆PLR, ∆NLR and T2DM risk were analyzed using the Cox regression model with corresponding Hazard Ratios (HRs) and 95% Confidence Intervals (CIs). PLR exhibited significant correlation with T2DM risk in a linear reverse dose–response pattern, the corresponding HRs and 95% CIs were 0.81 (0.72, 0.90), 0.71 (0.63, 0.80) and 0.56 (0.49, 0.64) respectively (Ptrend < 0.001) for Q2, Q3 and Q4 vs Q1 after adjusting for age, gender, BMI, TG, TC, HDL-C, FPG, ALT, AST, heart rate, smoking, family history of diabetes, and alcohol consumption at baseline in Model 3. The significance remained in subgroups of women, <45 years, ≥45 years, BMI ≥ 24, with fatty liver disease, without fatty liver disease and normotension. Comparing with the largest decrease group of NLR (∆NLR < −0.32), the risk of T2DM increased for −0.003 ≤ ∆NLR < 0.31 (HR 1.17, 95% CI 1.01–1.36) and ∆NLR ≥ 0.31 (HR 1.23, 95% CI 1.06–1.43). Higher PLR could reduce the risk of T2DM. Larger increase of NLR could increase T2DM risk.",
"descriptionType": "Abstract"
}
],
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"fundingReferences": [],
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{
"relationType": "IsSupplementTo",
"relatedIdentifier": "10.1080/07435800.2022.2127757",
"relatedIdentifierType": "DOI"
}
],
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"state": "findable"
}