{
"id": "https://doi.org/10.25493/qn6k-chn",
"doi": "10.25493/QN6K-CHN",
"url": "https://kg.ebrains.eu/search/instances/Dataset/8aa589112382069c4fe65ef0a645d478",
"types": {
"ris": "DATA",
"bibtex": "misc",
"citeproc": "dataset",
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"creators": [
{
"name": "Zilles, K.",
"nameType": "Personal",
"givenName": "K.",
"familyName": "Zilles",
"affiliation": [],
"nameIdentifiers": []
},
{
"name": "Palomero-Gallagher, N.",
"nameType": "Personal",
"givenName": "N.",
"familyName": "Palomero-Gallagher",
"affiliation": [],
"nameIdentifiers": []
},
{
"name": "Amunts, K.",
"nameType": "Personal",
"givenName": "K.",
"familyName": "Amunts",
"affiliation": [],
"nameIdentifiers": []
},
{
"name": "Friederici, A.",
"nameType": "Personal",
"givenName": "A.",
"familyName": "Friederici",
"affiliation": [],
"nameIdentifiers": []
},
{
"name": "Caspers, J.",
"nameType": "Personal",
"givenName": "J.",
"familyName": "Caspers",
"affiliation": [],
"nameIdentifiers": []
}
],
"titles": [
{
"title": "Density measurements of different receptors for Area FG1 (FusG) [human, v1.0]"
}
],
"publisher": {
"name": "Human Brain Project Neuroinformatics Platform"
},
"container": {},
"subjects": [
{
"subject": "Neuroscience"
}
],
"contributors": [
{
"name": "Zilles, Karl",
"nameType": "Personal",
"givenName": "Karl",
"familyName": "Zilles",
"affiliation": [],
"contributorType": "ContactPerson",
"nameIdentifiers": []
},
{
"name": "Palomero-Gallagher, Nicola",
"nameType": "Personal",
"givenName": "Nicola",
"familyName": "Palomero-Gallagher",
"affiliation": [],
"contributorType": "ContactPerson",
"nameIdentifiers": []
}
],
"dates": [
{
"date": "2018-10-25",
"dateType": "Issued"
},
{
"date": "2018-03-31",
"dateType": "Available"
}
],
"publicationYear": 2018,
"identifiers": [],
"sizes": [],
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"rightsList": [
{
"rights": "Creative Commons Attribution Non Commercial Share Alike 4.0 International",
"rightsUri": "https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode",
"schemeUri": "https://spdx.org/licenses/",
"rightsIdentifier": "cc-by-nc-sa-4.0",
"rightsIdentifierScheme": "SPDX"
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],
"descriptions": [
{
"description": "This dataset contains the densities (in fmol/mg protein) of receptors for classical neurotransmitters in Area FG1 (FusG) obtained by means of quantitative _in vitro_ autoradiography. The receptor densities are visualized as _fingerprints_ (**fp**), which provide the mean density and standard deviation for each of the analyzed receptor types, averaged across samples. Overview of available measurements [ **receptor** \\| **_neurotransmitter_** \\| _labeling agent_ ]: **AMPA** \\| **_glutamate_** \\| _[3H]AMPA_ **kainate** \\| **_glutamate_** \\| _[3H]kainate_ **NMDA** \\| **_glutamate_** \\| _[3H]MK-801_ **mGluR2/3** \\| **_glutamate_** \\| _[3H]LY341495_ **GABAA** \\| **_GABA_** \\| _[3H]muscimol_ **GABAB** \\| **_GABA_** \\| _[3H]CGP54626_ **GABAA/BZ** \\| **_GABA_** \\| _[3H]flumazenil_ **muscarinic M1** \\| **_acetylcholine_** \\| _[3H]pirenzepine_ **muscarinic M2** \\| **_acetylcholine_** \\| _[3H]oxotremorine-M_ **muscarinic M3** \\| **_acetylcholine_** \\| _[3H]4-DAMP_ **nicotinic α4β2** \\| **_acetylcholine_** \\| _[3H]epibatidine_ **α1** \\| **_noradrenalin/norepinephrine_** \\| _[3H]prazosin_ **α2** \\| **_noradrenalin/norepinephrine_** \\| _[3H]UK-14,304_ **5-HT1A** \\| **_serotonin_** \\| _[3H]8-OH-DPAT_ **5-HT2** \\| **_serotonin_** \\| _[3H]ketanserin_ **D1** \\| **_dopamine_** \\| _[3H]SCH23390_ For exemplary samples, we also provide laminar _profiles_ (**pr**) and/or color-coded laminar _autoradiography_ images (**ar**). The density profiles provide, for a single tissue sample, an exemplary density distribution for a single receptor from the pial surface to the border between layer VI and the white matter. The autoradiography images show an exemplary density distribution of a single receptor for one laminar cross-section in a single tissue sample. Information on the used tissue samples and corresponding subjects for the receptor fingerprints, profiles and autoradiographs as well as a list of analyzed receptors accompanies the provided dataset. **For methodological details, see:** Zilles, K. et al. (2002). Quantitative analysis of cyto- and receptorarchitecture of the human brain, pp. 573-602. In: Brain Mapping: The Methods, 2nd edition (A.W. Toga and J.C. Mazziotta, eds.). San Diego, Academic Press. Palomero-Gallagher N, Zilles K. (2018) Cyto- and receptorarchitectonic mapping of the human brain. In: Handbook of Clinical Neurology 150: 355-387",
"descriptionType": "Abstract"
}
],
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"relatedIdentifiers": [
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"relationType": "IsDocumentedBy",
"relatedIdentifier": "10.1007/s00429-013-0646-z",
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"relatedIdentifier": "10.1016/j.cortex.2014.07.007",
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