{"data":{"id":"10.6084/m9.figshare.c.4155764","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.4155764","prefix":"10.6084","suffix":"m9.figshare.c.4155764","identifiers":[{"identifier":"https://doi.org/10.6084/m9.figshare.c.4155764","identifierType":"DOI"}],"alternateIdentifiers":[{"alternateIdentifierType":"DOI","alternateIdentifier":"https://doi.org/10.6084/m9.figshare.c.4155764"}],"creators":[{"name":"Pan, An","nameType":"Personal","givenName":"An","familyName":"Pan","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Yan","nameType":"Personal","givenName":"Yan","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Wen, Kai","nameType":"Personal","givenName":"Kai","familyName":"Wen","affiliation":[],"nameIdentifiers":[]},{"name":"Meiling Zhou","affiliation":[],"nameIdentifiers":[]},{"name":"Junwei Min","affiliation":[],"nameIdentifiers":[]},{"name":"Lei, Ming","nameType":"Personal","givenName":"Ming","familyName":"Lei","affiliation":[],"nameIdentifiers":[]},{"name":"Baoli Yao","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Subwavelength resolution Fourier ptychography with hemispherical digital condensers"}],"publisher":"Figshare","container":{},"publicationYear":2018,"subjects":[{"subject":"100509 Video Communications","subjectScheme":"FOR"},{"subject":"FOS: Electrical engineering, electronic engineering, information engineering","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2018-07-06","dateType":"Created"},{"date":"2018-08-23","dateType":"Updated"},{"date":"2018","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1364/oe.26.023119","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"CC BY 4.0","rightsUri":"https://creativecommons.org/licenses/by/4.0"}],"descriptions":[{"description":"Fourier ptychography (FP) is a promising computational imaging technique that overcomes the physical space-bandwidth product (SBP) limit of a conventional microscope by applying angular-varied illuminations. However, to date, the effective imaging numerical aperture (NA) achievable with a commercial LED board is still limited to the range of 0.3−0.7 with a 4×/0.1NA objective due to the geometric constraint with the declined illumination intensities and attenuated signal-to-noise ratio (SNR). Thus the highest achievable half-pitch resolution is usually constrained between 500−1000 nm, which cannot meet the requirements of high-resolution biomedical imaging applications. Although it is possible to improve the resolution by using a high-NA objective lens, the FP approach is less appealing as the decrease of field-of-view (FOV) will far exceed the improvement of spatial resolution in this case. Herein, in this paper, we initially present a subwavelength resolution Fourier ptychography (SRFP) platform with a hemispherical digital condenser to provide high-angle programmable plane-wave illuminations of 0.95NA, attaining a 4×/0.1NA objective with the final effective imaging performance of 1.05NA at a half-pitch resolution of 244 nm with the incident wavelength of 465 nm across a wide FOV of 14.60 mm², corresponding to a SBP of 245 megapixels. Our work provides an essential step of FP towards high-throughput imaging applications.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://figshare.com/collections/Subwavelength_resolution_Fourier_ptychography_with_hemispherical_digital_condensers/4155764","contentUrl":null,"metadataVersion":1,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":1,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2018-08-23T18:33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