{"data":{"id":"10.6084/m9.figshare.c.3261559","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.3261559","prefix":"10.6084","suffix":"m9.figshare.c.3261559","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Diaz, Jorge R. A.","nameType":"Personal","givenName":"Jorge R. A.","familyName":"Diaz","affiliation":[],"nameIdentifiers":[]},{"name":"Baldo, Martín Fernández","nameType":"Personal","givenName":"Martín Fernández","familyName":"Baldo","affiliation":[],"nameIdentifiers":[]},{"name":"Echeverría, Gustavo","nameType":"Personal","givenName":"Gustavo","familyName":"Echeverría","affiliation":[],"nameIdentifiers":[]},{"name":"Baldoni, Héctor","nameType":"Personal","givenName":"Héctor","familyName":"Baldoni","affiliation":[],"nameIdentifiers":[]},{"name":"Vullo, Daniela","nameType":"Personal","givenName":"Daniela","familyName":"Vullo","affiliation":[],"nameIdentifiers":[]},{"name":"Soria, Delia B.","nameType":"Personal","givenName":"Delia B.","familyName":"Soria","affiliation":[],"nameIdentifiers":[]},{"name":"Supuran, Claudiu T.","nameType":"Personal","givenName":"Claudiu T.","familyName":"Supuran","affiliation":[],"nameIdentifiers":[]},{"name":"Camí, Gerardo E.","nameType":"Personal","givenName":"Gerardo E.","familyName":"Camí","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"A substituted sulfonamide and its Co (II), Cu (II), and Zn (II) complexes as potential antifungal agents"}],"publisher":"Figshare","container":{},"publicationYear":2016,"subjects":[{"subject":"Biophysics"},{"subject":"Biochemistry"},{"subject":"29999 Physical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Physical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Physical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Medicine"},{"subject":"Pharmacology"},{"subject":"59999 Environmental Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Earth and related environmental sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Earth and related environmental sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"39999 Chemical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Chemical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Sociology"},{"subject":"FOS: Sociology","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Sociology","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Mental Health"}],"contributors":[],"dates":[{"date":"2016-05-27","dateType":"Created"},{"date":"2016-05-27","dateType":"Updated"},{"date":"2016","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsSupplementTo","relatedIdentifier":"10.1080/14756366.2016.1187143","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"CC-BY","rightsUri":"http://creativecommons.org/licenses/by/3.0/us"}],"descriptions":[{"description":"A sulfonamide 1-tosyl-1-\u003ci\u003eH\u003c/i\u003e-benzo(\u003ci\u003ed\u003c/i\u003e)imidazol-2-amine (TBZA) and three new complexes of Co(II), Cu(II), and Zn(II) have been synthesized. The compounds have been characterized by elemental analyses, FTIR, \u003csup\u003e1\u003c/sup\u003eH, and \u003csup\u003e13\u003c/sup\u003eC-NMR spectroscopy. The structure of the TBZA, and its Co(II) and Cu(II) complexes, was determined by X-ray diffraction methods. TBZA and its Co(II) complex crystallize in the triclinic \u003ci\u003eP\u003c/i\u003e-1 space group, while the Cu(II) complex crystallizes in the monoclinic P2\u003csub\u003e1\u003c/sub\u003e/c space group. Antifungal activity was screened against eight pathogenic yeasts: \u003ci\u003eCandida albicans\u003c/i\u003e (DMic 972576), \u003ci\u003eCandida krusei\u003c/i\u003e (DMic 951705), \u003ci\u003eCandida glabrata\u003c/i\u003e (DMic 982882), \u003ci\u003eCandida tropicalis\u003c/i\u003e (DMic 982884), \u003ci\u003eCandida dubliniensis\u003c/i\u003e (DMic 93695), \u003ci\u003eCandida guilliermondii\u003c/i\u003e (DMic 021150), \u003ci\u003eCryptococcus neoformans\u003c/i\u003e (ATCC 24067), and \u003ci\u003eCryptococcus gattii\u003c/i\u003e (ATCC MYA-4561). Results on the inhibition of various human (h) CAs, hCA I, II, IV, VII, IX, and XII, and pathogenic beta and gamma CAs are also reported.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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