{"data":{"id":"10.6084/m9.figshare.c.2175012","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2175012","prefix":"10.6084","suffix":"m9.figshare.c.2175012","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Wang, Bao-Lei","givenName":"Bao-Lei","familyName":"Wang","affiliation":[],"nameIdentifiers":[]},{"name":"Zhan, Yi-Zhou","givenName":"Yi-Zhou","familyName":"Zhan","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Li-Yuan","givenName":"Li-Yuan","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Yan","givenName":"Yan","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Xiao","givenName":"Xiao","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Li, Zheng-Ming","givenName":"Zheng-Ming","familyName":"Li","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Synthesis and Fungicidal Activities of Novel 1,2,4-Triazole Thione Derivatives Containing 1,2,3-Triazole and Substituted Piperazine Moieties"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2016,"subjects":[{"subject":"Biochemistry"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biotechnology"},{"subject":"Chemical Sciences not elsewhere classified"},{"subject":"Ecology"},{"subject":"Sociology"},{"subject":"FOS: Sociology","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Infectious Diseases"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Plant Biology"},{"subject":"Virology"}],"contributors":[],"dates":[{"date":"2016-01-18","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2016","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A series of novel 1,2,4-triazole thione derivatives containing 1,2,3-triazole and substituted piperazine moieties were synthesized via the Mannich reaction of 1,2,3-triazole-containing 1,2,4-triazole thiol intermediates with various substituted piperazines and formaldehyde in high yields. The structures of 14 title compounds were confirmed by melting points, IR, \u003csup\u003e1\u003c/sup\u003eH NMR, \u003csup\u003e13\u003c/sup\u003eC NMR, and elemental analysis. The bioassay results showed that some of the title compounds exhibit significant fungicidal activities against several plant fungi at 50 μg/mL, especially trifluoromethyl-containing triazole thione derivative \u003cb\u003e9g\u003c/b\u003e showed broad activities and could be made further structural optimization for novel fungicides innovation research.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/collections/Synthesis_and_Fungicidal_Activities_of_Novel_1_2_4_Triazole_Thione_Derivatives_Containing_1_2_3_Triazole_and_Substituted_Piperazine_Moieties/2175012","contentUrl":null,"metadataVersion":3,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2016-01-18T13:33:18.000Z","registered":"2016-01-18T13:33:19.000Z","published":"2016","updated":"2024-03-21T11:24:30.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.c.2175012","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}