{"data":{"id":"10.6084/m9.figshare.c.2174291.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2174291.v1","prefix":"10.6084","suffix":"m9.figshare.c.2174291.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Zhang, Yan-Jun","givenName":"Yan-Jun","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Huang, Yan","givenName":"Yan","familyName":"Huang","affiliation":[],"nameIdentifiers":[]},{"name":"Li, Jun","givenName":"Jun","familyName":"Li","affiliation":[],"nameIdentifiers":[]},{"name":"Wu, Liang-Deng","givenName":"Liang-Deng","familyName":"Wu","affiliation":[],"nameIdentifiers":[]},{"name":"Xiong, Chun-Lan","givenName":"Chun-Lan","familyName":"Xiong","affiliation":[],"nameIdentifiers":[]},{"name":"Chen, Zi-Zhan","givenName":"Zi-Zhan","familyName":"Chen","affiliation":[],"nameIdentifiers":[]},{"name":"He, Rui-Jie","givenName":"Rui-Jie","familyName":"He","affiliation":[],"nameIdentifiers":[]},{"name":"Deng, Sheng-Ping","givenName":"Sheng-Ping","familyName":"Deng","affiliation":[],"nameIdentifiers":[]},{"name":"Yang, Rui-Yun","givenName":"Rui-Yun","familyName":"Yang","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"A new flavane acid from the fruits of \u003ci\u003eIllicium verum\u003c/i\u003e"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2016,"subjects":[{"subject":"Biological Sciences"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biotechnology"},{"subject":"Microbiology"},{"subject":"Biochemistry"},{"subject":"Biophysics"}],"contributors":[],"dates":[{"date":"2016-01-08","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2016","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.2174291","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A new compound, illiciumflavane acid (\u003cb\u003e1\u003c/b\u003e), along with 13 known compounds (2–14), were isolated from the fruits of \u003ci\u003eIllicium verum\u003c/i\u003e Hook. F. Their structures were elucidated through various spectroscopic methods, including 1D NMR (\u003csup\u003e1\u003c/sup\u003eH NMR, \u003csup\u003e13\u003c/sup\u003eC NMR), 2D NMR (HMQC, HMBC and NOESY) and HRMS. The stereochemistry at the chiral centres was determined using CD spectrum as well as analyses of coupling constants and optical rotation data. Cytotoxicity evaluation of four compounds showed that illiciumflavane acid and (\u003ci\u003eE\u003c/i\u003e)-1,2-bis(4-methoxyphenyl)ethene exhibited potential against A549 activities with IC\u003csub\u003e50\u003c/sub\u003e values of 4.63 μM and 9.17 μM, respectively.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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