{"data":{"id":"10.6084/m9.figshare.c.2168006","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2168006","prefix":"10.6084","suffix":"m9.figshare.c.2168006","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Catalán, Julia","nameType":"Personal","givenName":"Julia","familyName":"Catalán","affiliation":[],"nameIdentifiers":[]},{"name":"Siivola, Kirsi M.","nameType":"Personal","givenName":"Kirsi M.","familyName":"Siivola","affiliation":[],"nameIdentifiers":[]},{"name":"Nymark, Penny","nameType":"Personal","givenName":"Penny","familyName":"Nymark","affiliation":[],"nameIdentifiers":[]},{"name":"Lindberg, Hanna","nameType":"Personal","givenName":"Hanna","familyName":"Lindberg","affiliation":[],"nameIdentifiers":[]},{"name":"Suhonen, Satu","nameType":"Personal","givenName":"Satu","familyName":"Suhonen","affiliation":[],"nameIdentifiers":[]},{"name":"Järventaus, Hilkka","nameType":"Personal","givenName":"Hilkka","familyName":"Järventaus","affiliation":[],"nameIdentifiers":[]},{"name":"Koivisto, Antti J.","nameType":"Personal","givenName":"Antti J.","familyName":"Koivisto","affiliation":[],"nameIdentifiers":[]},{"name":"Moreno, Carlos","nameType":"Personal","givenName":"Carlos","familyName":"Moreno","affiliation":[],"nameIdentifiers":[]},{"name":"Vanhala, Esa","nameType":"Personal","givenName":"Esa","familyName":"Vanhala","affiliation":[],"nameIdentifiers":[]},{"name":"Wolff, Henrik","nameType":"Personal","givenName":"Henrik","familyName":"Wolff","affiliation":[],"nameIdentifiers":[]},{"name":"Kling, Kirsten I.","nameType":"Personal","givenName":"Kirsten I.","familyName":"Kling","affiliation":[],"nameIdentifiers":[]},{"name":"Jensen, Keld Alstrup","nameType":"Personal","givenName":"Keld Alstrup","familyName":"Jensen","affiliation":[],"nameIdentifiers":[]},{"name":"Savolainen, Kai","nameType":"Personal","givenName":"Kai","familyName":"Savolainen","affiliation":[],"nameIdentifiers":[]},{"name":"Norppa, Hannu","nameType":"Personal","givenName":"Hannu","familyName":"Norppa","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"\u003ci\u003eIn vitro\u003c/i\u003e and \u003ci\u003ein vivo\u003c/i\u003e genotoxic effects of straight versus tangled multi-walled carbon nanotubes"}],"publisher":"Figshare","container":{},"publicationYear":2016,"subjects":[{"subject":"Biophysics"},{"subject":"Biochemistry"},{"subject":"Space Science"},{"subject":"29999 Physical Sciences not elsewhere classified","subjectScheme":"FOR"},{"subject":"FOS: Physical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Physical sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Medicine"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"FOS: Biological sciences","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Cell Biology"},{"subject":"Molecular Biology"},{"subject":"Physiology"},{"subject":"Pharmacology"},{"subject":"Biotechnology"},{"subject":"Developmental Biology"},{"subject":"Cancer"},{"subject":"Mental Health"},{"subject":"Hematology"}],"contributors":[],"dates":[{"date":"2015-12-17","dateType":"Created"},{"date":"2016-05-11","dateType":"Updated"},{"date":"2016","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"CC-BY","rightsUri":"http://creativecommons.org/licenses/by/3.0/us"}],"descriptions":[{"description":"Some multi-walled carbon nanotubes (MWCNTs) induce mesothelioma in rodents, straight MWCNTs showing a more pronounced effect than tangled MWCNTs. As primary and secondary genotoxicity may play a role in MWCNT carcinogenesis, we used a battery of assays for DNA damage and micronuclei to compare the genotoxicity of straight (MWCNT-S) and tangled MWCNTs (MWCNT-T) \u003ci\u003ein vitro\u003c/i\u003e (primary genotoxicity) and \u003ci\u003ein vivo\u003c/i\u003e (primary or secondary genotoxicity). C57Bl/6 mice showed a dose-dependent increase in DNA strand breaks, as measured by the comet assay, in lung cells 24 h after a single pharyngeal aspiration of MWCNT-S (1–200 μg/mouse). An increase was also observed for DNA strand breaks in lung and bronchoalveolar lavage (BAL) cells and for micronucleated alveolar type II cells in mice exposed to aerosolized MWCNT-S (8.2–10.8 mg/m\u003csup\u003e3\u003c/sup\u003e) for 4 d, 4 h/d. No systemic genotoxic effects, assessed by the γ-H2AX assay in blood mononuclear leukocytes or by micronucleated polychromatic erythrocytes (MNPCEs) in bone marrow or blood, were observed for MWCNT-S by either exposure technique. MWCNT-T showed a dose-related \u003ci\u003edecrease\u003c/i\u003e in DNA damage in BAL and lung cells of mice after a single pharyngeal aspiration (1–200 μg/mouse) and in MNPCEs after inhalation exposure (17.5 mg/m\u003csup\u003e3\u003c/sup\u003e). \u003ci\u003eIn vitro\u003c/i\u003e in human bronchial epithelial BEAS-2B cells, MWCNT-S induced DNA strand breaks at low doses (5 and 10 μg/cm\u003csup\u003e2\u003c/sup\u003e), while MWCNT-T increased strand breakage only at 200 μg/cm\u003csup\u003e2\u003c/sup\u003e. Neither of the MWCNTs was able to induce micronuclei \u003ci\u003ein vitro\u003c/i\u003e. Our findings suggest that both primary and secondary mechanisms may be involved in the genotoxicity of straight MWCNTs.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"<?xml version="1.0" encoding="UTF-8"?>
<resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4/metadata.xsd">
  <identifier identifierType="DOI">10.6084/M9.FIGSHARE.C.2168006</identifier>
  <creators>
    <creator>
      <creatorName nameType="Personal">Catalán, Julia</creatorName>
      <givenName>Julia</givenName>
      <familyName>Catalán</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Siivola, Kirsi M.</creatorName>
      <givenName>Kirsi M.</givenName>
      <familyName>Siivola</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Nymark, Penny</creatorName>
      <givenName>Penny</givenName>
      <familyName>Nymark</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Lindberg, Hanna</creatorName>
      <givenName>Hanna</givenName>
      <familyName>Lindberg</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Suhonen, Satu</creatorName>
      <givenName>Satu</givenName>
      <familyName>Suhonen</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Järventaus, Hilkka</creatorName>
      <givenName>Hilkka</givenName>
      <familyName>Järventaus</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Koivisto, Antti J.</creatorName>
      <givenName>Antti J.</givenName>
      <familyName>Koivisto</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Moreno, Carlos</creatorName>
      <givenName>Carlos</givenName>
      <familyName>Moreno</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Vanhala, Esa</creatorName>
      <givenName>Esa</givenName>
      <familyName>Vanhala</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Wolff, Henrik</creatorName>
      <givenName>Henrik</givenName>
      <familyName>Wolff</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Kling, Kirsten I.</creatorName>
      <givenName>Kirsten I.</givenName>
      <familyName>Kling</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Jensen, Keld Alstrup</creatorName>
      <givenName>Keld Alstrup</givenName>
      <familyName>Jensen</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Savolainen, Kai</creatorName>
      <givenName>Kai</givenName>
      <familyName>Savolainen</familyName>
    </creator>
    <creator>
      <creatorName nameType="Personal">Norppa, Hannu</creatorName>
      <givenName>Hannu</givenName>
      <familyName>Norppa</familyName>
    </creator>
  </creators>
  <titles>
    <title>&lt;i&gt;In vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt; genotoxic effects of straight versus tangled multi-walled carbon nanotubes</title>
  </titles>
  <publisher>Figshare</publisher>
  <publicationYear>2016</publicationYear>
  <resourceType resourceTypeGeneral="Collection">Collection</resourceType>
  <subjects>
    <subject>Biophysics</subject>
    <subject>Biochemistry</subject>
    <subject>Space Science</subject>
    <subject subjectScheme="FOR">29999 Physical Sciences not elsewhere classified</subject>
    <subject subjectScheme="Fields of Science and Technology (FOS)" schemeURI="http://www.oecd.org/science/inno/38235147.pdf">FOS: Physical sciences</subject>
    <subject subjectScheme="Fields of Science and Technology (FOS)">FOS: Physical sciences</subject>
    <subject>Medicine</subject>
    <subject>Microbiology</subject>
    <subject subjectScheme="Fields of Science and Technology (FOS)" schemeURI="http://www.oecd.org/science/inno/38235147.pdf">FOS: Biological sciences</subject>
    <subject subjectScheme="Fields of Science and Technology (FOS)">FOS: Biological sciences</subject>
    <subject>Cell Biology</subject>
    <subject>Molecular Biology</subject>
    <subject>Physiology</subject>
    <subject>Pharmacology</subject>
    <subject>Biotechnology</subject>
    <subject>Developmental Biology</subject>
    <subject>Cancer</subject>
    <subject>Mental Health</subject>
    <subject>Hematology</subject>
  </subjects>
  <dates>
    <date dateType="Created">2015-12-17</date>
    <date dateType="Updated">2016-05-11</date>
    <date dateType="Issued">2016</date>
  </dates>
  <sizes/>
  <formats/>
  <version/>
  <rightsList>
    <rights rightsURI="http://creativecommons.org/licenses/by/3.0/us">CC-BY</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Some multi-walled carbon nanotubes (MWCNTs) induce mesothelioma in rodents, straight MWCNTs showing a more pronounced effect than tangled MWCNTs. As primary and secondary genotoxicity may play a role in MWCNT carcinogenesis, we used a battery of assays for DNA damage and micronuclei to compare the genotoxicity of straight (MWCNT-S) and tangled MWCNTs (MWCNT-T) &lt;i&gt;in vitro&lt;/i&gt; (primary genotoxicity) and &lt;i&gt;in vivo&lt;/i&gt; (primary or secondary genotoxicity). C57Bl/6 mice showed a dose-dependent increase in DNA strand breaks, as measured by the comet assay, in lung cells 24 h after a single pharyngeal aspiration of MWCNT-S (1–200 μg/mouse). An increase was also observed for DNA strand breaks in lung and bronchoalveolar lavage (BAL) cells and for micronucleated alveolar type II cells in mice exposed to aerosolized MWCNT-S (8.2–10.8 mg/m&lt;sup&gt;3&lt;/sup&gt;) for 4 d, 4 h/d. No systemic genotoxic effects, assessed by the γ-H2AX assay in blood mononuclear leukocytes or by micronucleated polychromatic erythrocytes (MNPCEs) in bone marrow or blood, were observed for MWCNT-S by either exposure technique. MWCNT-T showed a dose-related &lt;i&gt;decrease&lt;/i&gt; in DNA damage in BAL and lung cells of mice after a single pharyngeal aspiration (1–200 μg/mouse) and in MNPCEs after inhalation exposure (17.5 mg/m&lt;sup&gt;3&lt;/sup&gt;). &lt;i&gt;In vitro&lt;/i&gt; in human bronchial epithelial BEAS-2B cells, MWCNT-S induced DNA strand breaks at low doses (5 and 10 μg/cm&lt;sup&gt;2&lt;/sup&gt;), while MWCNT-T increased strand breakage only at 200 μg/cm&lt;sup&gt;2&lt;/sup&gt;. Neither of the MWCNTs was able to induce micronuclei &lt;i&gt;in vitro&lt;/i&gt;. Our findings suggest that both primary and secondary mechanisms may be involved in the genotoxicity of straight MWCNTs.</description>
  </descriptions>
</resource>
","url":"https://figshare.com/collections/_i_In_vitro_i_and_i_in_vivo_i_genotoxic_effects_of_straight_i_versus_i_tangled_multi_walled_carbon_nanotubes/2168006","contentUrl":null,"metadataVersion":4,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"api","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2015-12-17T15:24:38.000Z","registered":"2015-12-17T15:24:39.000Z","published":"2016","updated":"2024-12-12T12:49:41.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.c.2168006","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}