{"data":{"id":"10.6084/m9.figshare.c.2166872.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2166872.v1","prefix":"10.6084","suffix":"m9.figshare.c.2166872.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Sin, Mei-Chan","givenName":"Mei-Chan","familyName":"Sin","affiliation":[],"nameIdentifiers":[]},{"name":"Higuchi, Akon","givenName":"Akon","familyName":"Higuchi","affiliation":[],"nameIdentifiers":[]},{"name":"Zheng, Jie","givenName":"Jie","familyName":"Zheng","affiliation":[],"nameIdentifiers":[]},{"name":"Chang, Yung","givenName":"Yung","familyName":"Chang","affiliation":[],"nameIdentifiers":[]},{"name":"Lin, Wen-Lin","givenName":"Wen-Lin","familyName":"Lin","affiliation":[],"nameIdentifiers":[]},{"name":"Chen, Jeff","givenName":"Jeff","familyName":"Chen","affiliation":[],"nameIdentifiers":[]},{"name":"Chinnathambi, Arunachalam","givenName":"Arunachalam","familyName":"Chinnathambi","affiliation":[],"nameIdentifiers":[]},{"name":"Alharbi, Sulaiman Ali","givenName":"Sulaiman Ali","familyName":"Alharbi","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Hemocompatible Interface Control via Thermal-Activated Bio-Inspired Surface PEGylation"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Hematology"},{"subject":"Inorganic Chemistry"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Developmental Biology"},{"subject":"Biological Sciences"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Meta Science"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Evolutionary Biology"},{"subject":"Biotechnology"},{"subject":"Physiology"},{"subject":"Cell Biology"},{"subject":"Microbiology"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-17","dateType":"Created"},{"date":"2019-08-20","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsPreviousVersionOf","relatedIdentifier":"10.6084/m9.figshare.c.2166872","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A facile thermal-activated self-copolymerization coating of antifouling layers was designed. PEGylated poly(ethyleneimine) (PEI-PEGMA) was first synthesized, mixed with an alkaline dopamine solution, and then concurrently co-deposited onto versatile substrates of both organic and inorganic materials. Thermal-activated co-deposition of dopamine/PEI-PEGMA could then proceed, giving rise to good hemocompatible performance in respect to low fibrinogen adsorption, ultra-low blood cell adhesion and activation, and almost undetectable hemolytic activities. This work also revealed that the hemocompatible performance was contributed by PEGylated PEI but not dopamine since the poly(dopamine)-coating was shown to induce a high level of fibrinogen adsorption as well as vigorous platelet activation.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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