{"data":{"id":"10.6084/m9.figshare.c.2166872","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2166872","prefix":"10.6084","suffix":"m9.figshare.c.2166872","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Sin, Mei-Chan","givenName":"Mei-Chan","familyName":"Sin","affiliation":[],"nameIdentifiers":[]},{"name":"Lin, Wen-Lin","givenName":"Wen-Lin","familyName":"Lin","affiliation":[],"nameIdentifiers":[]},{"name":"Chang-Hung Chen, Jeff","givenName":"Jeff","familyName":"Chang-Hung Chen","affiliation":[],"nameIdentifiers":[]},{"name":"Higuchi, Akon","givenName":"Akon","familyName":"Higuchi","affiliation":[],"nameIdentifiers":[]},{"name":"Zheng, Jie","givenName":"Jie","familyName":"Zheng","affiliation":[],"nameIdentifiers":[]},{"name":"Chinnathambi, Arunachalam","givenName":"Arunachalam","familyName":"Chinnathambi","affiliation":[],"nameIdentifiers":[]},{"name":"Alharbi, Sulaiman Ali","givenName":"Sulaiman Ali","familyName":"Alharbi","affiliation":[],"nameIdentifiers":[]},{"name":"Chang, Yung","givenName":"Yung","familyName":"Chang","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Hemocompatible interface control via thermal-activated bio-inspired surface PEGylation"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Biochemistry"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Genetics"},{"subject":"Physiology"},{"subject":"Biotechnology"},{"subject":"Chemical Sciences not elsewhere classified"},{"subject":"Ecology"},{"subject":"Science Policy"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Developmental Biology"},{"subject":"Inorganic Chemistry"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Hematology"}],"contributors":[],"dates":[{"date":"2015-12-17","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A facile thermal-activated self-copolymerization coating of antifouling layers was designed. PEGylated poly(ethyleneimine) (PEI-PEGMA) was first synthesized, mixed with an alkaline dopamine solution, and then concurrently codeposited onto versatile substrates of both organic and inorganic materials. Thermal-activated codeposition of dopamine/PEI-PEGMA could then proceed, giving rise to good hemocompatible performance in respect to low fibrinogen adsorption, ultra-low blood cell adhesion and activation, and almost undetectable hemolytic activities. This work also revealed that the hemocompatible performance was contributed by PEGylated PEI but not dopamine, as the poly(dopamine)-coating was shown to induce a high level of fibrinogen adsorption as well as vigorous platelet activation.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/collections/Hemocompatible_Interface_Control_via_Thermal_Activated_Bio_Inspired_Surface_PEGylation/2166872","contentUrl":null,"metadataVersion":3,"schemaVersion":"h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