{"data":{"id":"10.6084/m9.figshare.c.2122022","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2122022","prefix":"10.6084","suffix":"m9.figshare.c.2122022","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Zeng, Biao","givenName":"Biao","familyName":"Zeng","affiliation":[],"nameIdentifiers":[]},{"name":"Liu, Guang-Da","givenName":"Guang-Da","familyName":"Liu","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Bao-Bao","givenName":"Bao-Bao","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Wang, Shan-shan","givenName":"Shan-shan","familyName":"Wang","affiliation":[],"nameIdentifiers":[]},{"name":"Ma, Rui","givenName":"Rui","familyName":"Ma","affiliation":[],"nameIdentifiers":[]},{"name":"Zhong, Bei-Shan","givenName":"Bei-Shan","familyName":"Zhong","affiliation":[],"nameIdentifiers":[]},{"name":"He, Bai-qiu","givenName":"Bai-qiu","familyName":"He","affiliation":[],"nameIdentifiers":[]},{"name":"Liang, Yan","givenName":"Yan","familyName":"Liang","affiliation":[],"nameIdentifiers":[]},{"name":"Wu, Fei-Hua","givenName":"Fei-Hua","familyName":"Wu","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"A new triterpenoid saponin from \u003ci\u003eClinopodium chinense\u003c/i\u003e (Benth.) O. Kuntze"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Biochemistry"},{"subject":"Space Science"},{"subject":"Pharmacology"},{"subject":"Chemical Sciences not elsewhere classified"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Sociology"},{"subject":"FOS: Sociology","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences not elsewhere classified"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A new triterpene saponin, 3\u003ci\u003eβ\u003c/i\u003e,16\u003ci\u003eβ\u003c/i\u003e,23\u003ci\u003eα\u003c/i\u003e,28\u003ci\u003eβ\u003c/i\u003e,30\u003ci\u003eβ\u003c/i\u003e-pentahydroxyl-olean-11,13(18)-dien-3\u003ci\u003eβ\u003c/i\u003e-yl-[\u003ci\u003eβ\u003c/i\u003e-d-glucopyranosyl-(1→2)]-[\u003ci\u003eβ\u003c/i\u003e-d-glucopyranosyl-(1→3)]-\u003ci\u003eβ\u003c/i\u003e-d-fucopyranoside, was named Clinoposaponin D (\u003cb\u003e1\u003c/b\u003e), together with six known triterpene saponins, buddlejasaponin IVb (\u003cb\u003e2\u003c/b\u003e), buddlejasaponin IVa (\u003cb\u003e3\u003c/b\u003e), buddlejasaponin IV (\u003cb\u003e4\u003c/b\u003e), clinopodisides D (\u003cb\u003e5\u003c/b\u003e), 11\u003ci\u003eα\u003c/i\u003e,16\u003ci\u003eβ\u003c/i\u003e,23,28-Tetrahydroxyolean-12-en-3\u003ci\u003eβ\u003c/i\u003e-yl-[\u003ci\u003eβ\u003c/i\u003e-d-glucopyranosyl-(1→2)]-[\u003ci\u003eβ\u003c/i\u003e-d-glucopyranosyl-(1→3)]-\u003ci\u003eβ\u003c/i\u003e-d-fucopyranoside (\u003cb\u003e6\u003c/b\u003e) and prosaikogenin A (\u003cb\u003e7\u003c/b\u003e), and two known triterpenes, saikogenin A (\u003cb\u003e8\u003c/b\u003e) and saikogenin F (\u003cb\u003e9\u003c/b\u003e) were isolated from \u003ci\u003eClinopodium chinense\u003c/i\u003e (Benth.) O. Kuntze. Their structures were elucidated on the basis of 1D, 2D NMR and MS analysis. Meanwhile, the effects of all compounds on rabbit platelet aggregation and thrombin time (TT) were investigated \u003ci\u003ein vitro\u003c/i\u003e. Compounds \u003cb\u003e4\u003c/b\u003e and \u003cb\u003e7\u003c/b\u003e had significant promoting effects on platelet aggregation with EC\u003csub\u003e50\u003c/sub\u003e value at 53.4 and 12.2 μM, respectively. In addition, the highest concentration (200 μM) of compounds \u003cb\u003e2\u003c/b\u003e and \u003cb\u003e9\u003c/b\u003e shortened TT by 20.6 and 25.1%, respectively.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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