{"data":{"id":"10.6084/m9.figshare.c.2092283.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2092283.v1","prefix":"10.6084","suffix":"m9.figshare.c.2092283.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Heun Kim, Manh","givenName":"Manh","familyName":"Heun Kim","affiliation":[],"nameIdentifiers":[]},{"name":"Ra Kim, So","givenName":"So","familyName":"Ra Kim","affiliation":[],"nameIdentifiers":[]},{"name":"Hwan Oh, Myeong","givenName":"Myeong","familyName":"Hwan Oh","affiliation":[],"nameIdentifiers":[]},{"name":"Hyeok Heo, Jun","givenName":"Jun","familyName":"Hyeok Heo","affiliation":[],"nameIdentifiers":[]},{"name":"Yin, Jun","givenName":"Jun","familyName":"Yin","affiliation":[],"nameIdentifiers":[]},{"name":"Won Lee, Min","givenName":"Min","familyName":"Won Lee","affiliation":[],"nameIdentifiers":[]},{"name":"Hee Park, Kwan","givenName":"Kwan","familyName":"Hee Park","affiliation":[],"nameIdentifiers":[]},{"name":"Jun Park, Kwang","givenName":"Kwang","familyName":"Jun Park","affiliation":[],"nameIdentifiers":[]},{"name":"Hoon Yoon, Ki","givenName":"Ki","familyName":"Hoon Yoon","affiliation":[],"nameIdentifiers":[]},{"name":"Hyung Yoon, Kyu","givenName":"Kyu","familyName":"Hyung Yoon","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Two new phenolic compounds from the leaves of \u003ci\u003eAlnus sibirica\u003c/i\u003e Fisch. ex Turcz."}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Inorganic Chemistry"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences"},{"subject":"Immunology"},{"subject":"FOS: Clinical medicine","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Cell Biology"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.2092283","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Two new phenolic compounds, 4-\u003ci\u003eO\u003c/i\u003e-glucopyranosyl-5-\u003ci\u003eO\u003c/i\u003e-caffeoylshikimic acid (\u003cb\u003e1\u003c/b\u003e) and 2,3-digalloyl oregonin (\u003cb\u003e2\u003c/b\u003e), were isolated along with eight known phenolic compounds (\u003cb\u003e3\u003c/b\u003e–\u003cb\u003e10\u003c/b\u003e) from an 80% acetone extract of \u003ci\u003eAlnus sibirica\u003c/i\u003e leaves. The chemical structures of these compounds were elucidated using 1D/2D nuclear magnetic resonance and high resolution-MS. The anti-oxidative activities of these compounds were determined by assaying their 1,1-diphenyl-2-picrylhydrazyl radical and nitroblue tetrazolium superoxide anion scavenging activity. All of the isolated phenolic compounds (\u003cb\u003e1\u003c/b\u003e–\u003cb\u003e10\u003c/b\u003e) exhibited potent anti-oxidative activities. In particular, \u003cb\u003e2\u003c/b\u003e and 4, which are diarylheptanoids, and \u003cb\u003e10\u003c/b\u003e which is ellagitannin exhibited excellent anti-oxidative activities with almost the same potency as that of the positive controls \u003ci\u003eL\u003c/i\u003e-ascorbic acid and allopurinol.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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