{"data":{"id":"10.6084/m9.figshare.c.2065901.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2065901.v1","prefix":"10.6084","suffix":"m9.figshare.c.2065901.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Lü, Hai-Ning","givenName":"Hai-Ning","familyName":"Lü","affiliation":[],"nameIdentifiers":[]},{"name":"Ma, Shuang-Gang","givenName":"Shuang-Gang","familyName":"Ma","affiliation":[],"nameIdentifiers":[]},{"name":"Liu, Yun-Bao","givenName":"Yun-Bao","familyName":"Liu","affiliation":[],"nameIdentifiers":[]},{"name":"Qu, Jing","givenName":"Jing","familyName":"Qu","affiliation":[],"nameIdentifiers":[]},{"name":"Li, Yong","givenName":"Yong","familyName":"Li","affiliation":[],"nameIdentifiers":[]},{"name":"Xu, Song","givenName":"Song","familyName":"Xu","affiliation":[],"nameIdentifiers":[]},{"name":"Zhu, Hua","givenName":"Hua","familyName":"Zhu","affiliation":[],"nameIdentifiers":[]},{"name":"Yu, Shi-Shan","givenName":"Shi-Shan","familyName":"Yu","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Sesquiterpenes from the roots of \u003ci\u003eIllicium oligandrum\u003c/i\u003e"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Virology"},{"subject":"Infectious Diseases"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences"},{"subject":"Ecology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.2065901","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Two new sesquiterpenes, oligandrin (\u003cb\u003e1\u003c/b\u003e) and oligandric acid (\u003cb\u003e2\u003c/b\u003e), together with three analogues, tashironin A (\u003cb\u003e3\u003c/b\u003e), tashironin (\u003cb\u003e4\u003c/b\u003e), and oplodiol (\u003cb\u003e5\u003c/b\u003e), were isolated from the roots of \u003ci\u003eIllicium oligandrum\u003c/i\u003e. The structures of new compounds were determined based on 1D and 2D NMR experiments and X-ray diffraction. Compound \u003cb\u003e1\u003c/b\u003e represents a presumed biosynthetic precursor of \u003ci\u003eseco\u003c/i\u003e-prezizaane sesquiterpenes which consists of a novel 6/6/5 tricarbocyclic skeleton. Compound \u003cb\u003e2\u003c/b\u003e is the first example of chamipinene-type sesquiterpene possessing a 6/4/6 tricyclic system from the genus \u003ci\u003eIllicium\u003c/i\u003e. Compounds \u003cb\u003e1\u003c/b\u003e–\u003cb\u003e5\u003c/b\u003e were evaluated \u003ci\u003ein vitro\u003c/i\u003e for their activity against coxsackie virus B3 (CVB3), influenza virus A/Hanfang/359/95 (H3N2), and influenza virus A/FM/1/47 (H1N1). Compound \u003cb\u003e1\u003c/b\u003e showed selective antiviral activity against CVB3 with IC\u003csub\u003e50\u003c/sub\u003e value of 11.11 μM.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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