{"data":{"id":"10.6084/m9.figshare.c.2038652.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2038652.v1","prefix":"10.6084","suffix":"m9.figshare.c.2038652.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Tao, Shipeng","givenName":"Shipeng","familyName":"Tao","affiliation":[],"nameIdentifiers":[]},{"name":"Hu, Qinquan","givenName":"Qinquan","familyName":"Hu","affiliation":[],"nameIdentifiers":[]},{"name":"Li, Huan","givenName":"Huan","familyName":"Li","affiliation":[],"nameIdentifiers":[]},{"name":"Ma, Shan","givenName":"Shan","familyName":"Ma","affiliation":[],"nameIdentifiers":[]},{"name":"Chen, Yunfeng","givenName":"Yunfeng","familyName":"Chen","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Synthesis of [1,2,3]Triazolo[5,1-\u003cb\u003e\u003ci\u003ea\u003c/i\u003e\u003c/b\u003e]isoquinoline Derivatives via a Selective Cascade Cyclization Sequence of 1,2-bis(Phenylethynyl)benzene Derivatives"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Infectious Diseases"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Science Policy"},{"subject":"Developmental Biology"},{"subject":"Biological Sciences"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Evolutionary Biology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Molecular Biology"},{"subject":"Cell Biology"},{"subject":"Microbiology"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.2038652","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A direct, concise, synthetic method for the generation of [1,2,3]triazolo[5,1-\u003ci\u003ea\u003c/i\u003e]isoquinoline derivatives, using a selective cascade cyclization of unsymmetrical substituted 1,2-bis(phenylethynyl)benzene derivatives with NaN\u003csub\u003e3\u003c/sub\u003e, has been developed. The reaction gave different substituted [1,2,3]triazolo[5,1-\u003ci\u003ea\u003c/i\u003e]isoquinolines in moderate to good yields. It was found that the substituents on the alkynes were important for the selectivities of the cascade cyclization sequences.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/collections/Synthesis_of_1_2_3_Triazolo_5_1_b_i_a_i_b_isoquinoline_Derivatives_via_a_Selective_Cascade_Cyclization_Sequence_of_1_2_bis_Phenylethynyl_benzene_Derivatives/2038652/1","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2015-12-05T19:44:36.000Z","registered":"2015-12-05T19:44:37.000Z","published":"2015","updated":"2024-03-21T08:39:14.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"p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