{"data":{"id":"10.6084/m9.figshare.c.2030384","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2030384","prefix":"10.6084","suffix":"m9.figshare.c.2030384","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Zhang, Xiaoning","givenName":"Xiaoning","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Wu, Xuan","givenName":"Xuan","familyName":"Wu","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Man","givenName":"Man","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Lin, Chen","givenName":"Chen","familyName":"Lin","affiliation":[],"nameIdentifiers":[]},{"name":"Jin, Can","givenName":"Can","familyName":"Jin","affiliation":[],"nameIdentifiers":[]},{"name":"Jiang, Juli","givenName":"Juli","familyName":"Jiang","affiliation":[],"nameIdentifiers":[]},{"name":"Wang, Leyong","givenName":"Leyong","familyName":"Wang","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"The recognition of \u003ci\u003en\u003c/i\u003e-alkyl phosphonic or carboxylic acid by mono-squaramide-functionalised pillar[5]arenes"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Infectious Diseases"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Evolutionary Biology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biotechnology"},{"subject":"Physiology"},{"subject":"Cell Biology"},{"subject":"Microbiology"},{"subject":"Biochemistry"},{"subject":"Biophysics"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"\u003cb\u003e:\u003c/b\u003e The synthesis of a novel mono-squaramide-functionalised pillar[5]arene \u003cb\u003e1a\u003c/b\u003e is reported, by which \u003ci\u003en\u003c/i\u003e-hexylphosphonic acid (HPA) or \u003ci\u003en\u003c/i\u003e-heptanoic acid (HA) could be recognised. The results of \u003csup\u003e1\u003c/sup\u003eH NMR titration, Job Plot, ESI-MS and 2D NMR experiments reveal that \u003cb\u003e1a\u003c/b\u003e forms a 1:1 stoichiometric complex with HPA and HA, respectively, and its association constants (log \u003ci\u003eK\u003c/i\u003e/M\u003csup\u003e− 1\u003c/sup\u003e) with HPA and HA are determined to be 3.83 ± 0.05 and 1.98 ± 0.04, respectively, suggesting much stronger binding ability of \u003cb\u003e1a\u003c/b\u003e with HPA over HA. To compare with \u003cb\u003e1a\u003c/b\u003e, \u003cb\u003e1b\u003c/b\u003e with the electron-withdrawing group (CF\u003csub\u003e3\u003c/sub\u003e) on the phenyl ring of squaramide moiety is synthesised as well, which shows the similar selective binding ability for HPA and HA but with a little stronger binding ability than \u003cb\u003e1a\u003c/b\u003e.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"PD94bWwgdmVyc2lvbj0iMS4wIiBlbmNvZGluZz0iVVRGLTgiPz4KPHJlc291cmNlIHhtbG5zPSJodHRwOi8vZGF0YWNpdGUub3JnL3NjaGVtYS9rZXJuZWwtNCIgeG1sbnM6eHNpPSJodHRwOi8vd3d3LnczLm9yZy8yMDAxL1hNTFNjaGVtYS1pbnN0YW5jZSIgeHNpOnNjaGVtYUxvY2F0aW9uPSJodHRwOi8vZGF0YWNpdGUub3JnL3NjaGVtYS9rZXJuZWwtNCBodHRwOi8vc2NoZW1hLmRhdGFjaXRlLm9yZy9tZXRhL2tlcm5lbC00LjQvbWV0YWRhdGEueHNkIj4KICA8aWRlbnRpZmllciBpZGVudGlmaWVyVHlwZT0iRE9JIj4xMC42MDg0L005LkZJR1NIQVJFLkMuMjAzMDM4NDwvaWRlbnRpZmllcj4KICA8Y3JlYXRvcnM+CiAgICA8Y3JlYXRvcj4KICAgICAgPGNyZWF0b3JOYW1lPlhpYW9uaW5nIFpoYW5nPC9jcmVhdG9yTmFtZT4KICAgICAgPGdpdmVuTmFtZT5YaWFvbmluZzwvZ2l2ZW5OYW1lPgogICAgICA8ZmFtaWx5TmFtZT5aaGFuZzwvZmFtaWx5TmFtZT4KICAgIDwvY3JlYXRvcj4KICAgIDxjcmVhdG9yPgogICAgICA8Y3JlYXRvck5hbWU+WHVhbiBXdTwvY3JlYXRvck5hbWU+CiAgICAgIDxnaXZlbk5hbWU+WHVhbjwvZ2l2ZW5OYW1lPgogICAgICA8ZmFtaWx5TmFtZT5XdTwvZmFtaWx5TmFtZT4KICAgIDwvY3JlYXRvcj4KICAgIDxjcmVhdG9yPgogICAgICA8Y3JlYXRvck5hbWU+TWFuIFpoYW5nPC9jcmVhdG9yTmFtZT4KICAgICAgPGdpdmVuTmFtZT5NYW48L2dpdmVuTmFtZT4KICAgICAgPGZhbWlseU5hbWU+Wmhhbmc8L2ZhbWlseU5hbWU+CiAgICA8L2NyZWF0b3I+CiAgICA8Y3JlYXRvcj4KICAgICAgPGNyZWF0b3JOYW1lPkNoZW4gTGluPC9jcmVhdG9yTmFtZT4KICAgICAgPGdpdmVuTmFtZT5DaGVuPC9naXZlbk5hbWU+CiAgICAgIDxmYW1pbHlOYW1lPkxpbjwvZmFtaWx5TmFtZT4KICAgIDwvY3JlYXRvcj4KICAgIDxjcmVhdG9yPgogICAgICA8Y3JlYXRvck5hbWU+Q2FuIEppbjwvY3JlYXRvck5hbWU+CiAgICAgIDxnaXZlbk5hbWU+Q2FuPC9naXZlbk5hbWU+CiAgICAgIDxmYW1pbHlOYW1lPkppbjwvZmFtaWx5TmFtZT4KICAgIDwvY3JlYXRvcj4KICAgIDxjcmVhdG9yPgogICAgICA8Y3JlYXRvck5hbWU+SnVsaSBKaWFuZzwvY3JlYXRvck5hbWU+CiAgICAgIDxnaXZlbk5hbWU+SnVsaTwvZ2l2ZW5OYW1lPgogICAgICA8ZmFtaWx5TmFtZT5KaWFuZzwvZmFtaWx5TmFtZT4KICAgIDwvY3JlYXRvcj4KICAgIDxjcmVhdG9yPgogICAgICA8Y3JlYXRvck5hbWU+TGV5b25nIFdhbmc8L2NyZWF0b3JOYW1lPgogICAgICA8Z2l2ZW5OYW1lPkxleW9uZzwvZ2l2ZW5OYW1lPgogICAgICA8ZmFtaWx5TmFtZT5XYW5nPC9mYW1pbHlOYW1lPgogICAgPC9jcmVhdG9yPgogIDwvY3JlYXRvcnM+CiAgPHRpdGxlcz4KICAgIDx0aXRsZT5UaGUgcmVjb2duaXRpb24gb2YgJmx0O2kmZ3Q7biZsdDsvaSZndDstYWxreWwgcGhvc3Bob25pYyBvciBjYXJib3h5bGljIGFjaWQgYnkgbW9uby1zcXVhcmFtaWRlLWZ1bmN0aW9uYWxpc2VkIHBpbGxhcls1XWFyZW5lczwvdGl0bGU+CiAgPC90aXRsZXM+CiAgPGRlc2NyaXB0aW9ucz4KICAgIDxkZXNjcmlwdGlvbiBkZXNjcmlwdGlvblR5cGU9IkFic3RyYWN0Ij4mbHQ7ZGl2Jmd0OyZsdDtwJmd0OyZsdDtiJmd0OzombHQ7L2ImZ3Q7IFRoZSBzeW50aGVzaXMgb2YgYSBub3ZlbCBtb25vLXNxdWFyYW1pZGUtZnVuY3Rpb25hbGlzZWQgcGlsbGFyWzVdYXJlbmUgJmx0O2ImZ3Q7MWEmbHQ7L2ImZ3Q7IGlzIHJlcG9ydGVkLCBieSB3aGljaCAmbHQ7aSZndDtuJmx0Oy9pJmd0Oy1oZXh5bHBob3NwaG9uaWMgYWNpZCAoSFBBKSBvciAmbHQ7aSZndDtuJmx0Oy9pJmd0Oy1oZXB0YW5vaWMgYWNpZCAoSEEpIGNvdWxkIGJlIHJlY29nbmlzZWQuIFRoZSByZXN1bHRzIG9mICZsdDtzdXAmZ3Q7MSZsdDsvc3VwJmd0O0ggTk1SIHRpdHJhdGlvbiwgSm9iIFBsb3QsIEVTSS1NUyBhbmQgMkQgTk1SIGV4cGVyaW1lbnRzIHJldmVhbCB0aGF0ICZsdDtiJmd0OzFhJmx0Oy9iJmd0OyBmb3JtcyBhIDE6MSBzdG9pY2hpb21ldHJpYyBjb21wbGV4IHdpdGggSFBBIGFuZCBIQSwgcmVzcGVjdGl2ZWx5LCBhbmQgaXRzIGFzc29jaWF0aW9uIGNvbnN0YW50cyAobG9nICZsdDtpJmd0O0smbHQ7L2kmZ3Q7L00mbHQ7c3VwJmd0O+KIksKgMSZsdDsvc3VwJmd0Oykgd2l0aCBIUEEgYW5kIEhBIGFyZSBkZXRlcm1pbmVkIHRvIGJlIDMuODPCoMKxwqAwLjA1IGFuZCAxLjk4wqDCscKgMC4wNCwgcmVzcGVjdGl2ZWx5LCBzdWdnZXN0aW5nIG11Y2ggc3Ryb25nZXIgYmluZGluZyBhYmlsaXR5IG9mICZsdDtiJmd0OzFhJmx0Oy9iJmd0OyB3aXRoIEhQQSBvdmVyIEhBLiBUbyBjb21wYXJlIHdpdGggJmx0O2ImZ3Q7MWEmbHQ7L2ImZ3Q7LCAmbHQ7YiZndDsxYiZsdDsvYiZndDsgd2l0aCB0aGUgZWxlY3Ryb24td2l0aGRyYXdpbmcgZ3JvdXAgKENGJmx0O3N1YiZndDszJmx0Oy9zdWImZ3Q7KSBvbiB0aGUgcGhlbnlsIHJpbmcgb2Ygc3F1YXJhbWlkZSBtb2lldHkgaXMgc3ludGhlc2lzZWQgYXMgd2VsbCwgd2hpY2ggc2hvd3MgdGhlIHNpbWlsYXIgc2VsZWN0aXZlIGJpbmRpbmcgYWJpbGl0eSBmb3IgSFBBIGFuZCBIQSBidXQgd2l0aCBhIGxpdHRsZSBzdHJvbmdlciBiaW5kaW5nIGFiaWxpdHkgdGhhbiAmbHQ7YiZndDsxYSZsdDsvYiZndDsuJmx0Oy9wJmd0OyZsdDsvZGl2Jmd0OzwvZGVzY3JpcHRpb24+CiAgPC9kZXNjcmlwdGlvbnM+CiAgPHN1YmplY3RzPgogICAgPHN1YmplY3Q+SW5mZWN0aW91cyBEaXNlYXNlczwvc3ViamVjdD4KICAgIDxzdWJqZWN0PkNoZW1pc3RyeTwvc3ViamVjdD4KICAgIDxzdWJqZWN0PkV2b2x1dGlvbmFyeSBCaW9sb2d5PC9zdWJqZWN0PgogICAgPHN1YmplY3Q+QmlvdGVjaG5vbG9neTwvc3ViamVjdD4KICAgIDxzdWJqZWN0PlBoeXNpb2xvZ3k8L3N1YmplY3Q+CiAgICA8c3ViamVjdD5DZWxsIEJpb2xvZ3k8L3N1YmplY3Q+CiAgICA8c3ViamVjdD5NaWNyb2Jpb2xvZ3k8L3N1YmplY3Q+CiAgICA8c3ViamVjdD5CaW9jaGVtaXN0cnk8L3N1YmplY3Q+CiAgICA8c3ViamVjdD5CaW9waHlzaWNzPC9zdWJqZWN0PgogIDwvc3ViamVjdHM+CiAgPHB1Ymxpc2hlcj5UYXlsb3IgJmFtcDsgRnJhbmNpczwvcHVibGlzaGVyPgogIDxwdWJsaWNhdGlvblllYXI+MjAxNTwvcHVibGljYXRpb25ZZWFyPgogIDxkYXRlcz4KICAgIDxkYXRlIGRhdGVUeXBlPSJDcmVhdGVkIj4yMDE1LTEyLTA1PC9kYXRlPgogICAgPGRhdGUgZGF0ZVR5cGU9IlVwZGF0ZWQiPjIwMTktMDgtMTk8L2RhdGU+CiAgPC9kYXRlcz4KICA8cmVzb3VyY2VUeXBlIHJlc291cmNlVHlwZUdlbmVyYWw9IkNvbGxlY3Rpb24iPkNvbGxlY3Rpb248L3Jlc291cmNlVHlwZT4KICA8cmlnaHRzTGlzdD4KICAgIDxyaWdodHMgcmlnaHRzVVJJPSJodHRwczovL2NyZWF0aXZlY29tbW9ucy5vcmcvbGljZW5zZXMvYnkvNC4wLyI+Q0MgQlkgNC4wPC9yaWdodHM+CiAgPC9yaWdodHNMaXN0Pgo8L3Jlc291cmNlPg==","url":"https://tandf.figshare.com/collections/The_recognition_of_i_n_i_alkyl_phosphonic_or_carboxylic_acid_by_mono_squaramide_functionalised_pillar_5_arenes/2030384","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"versionCount":0,"versionOfCount":0,"created":"2015-12-05T17:06:48.000Z","registered":"2015-12-05T17:06:49.000Z","published":"2015","updated":"2024-03-21T08:35:14.000Z"},"relationships":{"client":{"data":{"id":"figshare.ars","type":"clients"}},"provider":{"data":{"id":"otjm","type":"providers"}},"media":{"data":{"id":"10.6084/m9.figshare.c.2030384","type":"media"}},"references":{"data":[]},"citations":{"data":[]},"parts":{"data":[]},"partOf":{"data":[]},"versions":{"data":[]},"versionOf":{"data":[]}}}}