{"data":{"id":"10.6084/m9.figshare.c.2020865.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2020865.v1","prefix":"10.6084","suffix":"m9.figshare.c.2020865.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Chen, Wen-Hao","givenName":"Wen-Hao","familyName":"Chen","affiliation":[],"nameIdentifiers":[]},{"name":"Liu, Wen-Jie","givenName":"Wen-Jie","familyName":"Liu","affiliation":[],"nameIdentifiers":[]},{"name":"Wang, Yan","givenName":"Yan","familyName":"Wang","affiliation":[],"nameIdentifiers":[]},{"name":"Song, Xiao-Ping","givenName":"Xiao-Ping","familyName":"Song","affiliation":[],"nameIdentifiers":[]},{"name":"Chen, Guang-Ying","givenName":"Guang-Ying","familyName":"Chen","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"A new naphthoquinone and other antibacterial constituents from the roots of \u003ci\u003eXanthium sibiricum\u003c/i\u003e"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Infectious Diseases"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Developmental Biology"},{"subject":"Chemistry"},{"subject":"Biotechnology"},{"subject":"Pharmacology"},{"subject":"Biochemistry"},{"subject":"Biophysics"},{"subject":"Biological Sciences"},{"subject":"Earth and Environmental Sciences"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.2020865","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Reinvestigating the chemical constituents of the roots of \u003ci\u003eXanthium sibiricum\u003c/i\u003e led to the isolation of a new naphthoquinone (\u003cb\u003e1\u003c/b\u003e), together with 13 known compounds (\u003cb\u003e2\u003c/b\u003e–\u003cb\u003e14\u003c/b\u003e). Their structures were elucidated by using spectroscopic analyses, including HR-ESI-MS, 1D and 2D NMR, and by comparing their NMR data with those of related compounds. Compound \u003cb\u003e1\u003c/b\u003e showed moderate antibacterial activity against \u003ci\u003eEscherichia coli\u003c/i\u003e, \u003ci\u003eBacillus subtilis\u003c/i\u003e, \u003ci\u003eMicrococcus tetragenus\u003c/i\u003e and \u003ci\u003eStaphylococcus aureus\u003c/i\u003e, while \u003cb\u003e6\u003c/b\u003e and \u003cb\u003e12\u003c/b\u003e showed stronger antibacterial activity than the positive control ciprofloxacin against \u003ci\u003eE. coli\u003c/i\u003e, with minimum inhibitory concentration values of 0.17 and 0.35 μg/mL, respectively.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/collections/A_new_naphthoquinone_and_other_antibacterial_constituents_from_the_roots_of_i_Xanthium_sibiricum_i_/2020865/1","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCount":0,"citationCount":0,"citationsOverTime":[],"partCount":0,"partOfCount":0,"ve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