{"data":{"id":"10.6084/m9.figshare.c.2011808.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.2011808.v1","prefix":"10.6084","suffix":"m9.figshare.c.2011808.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Fredimoses, Mangaladoss","givenName":"Mangaladoss","familyName":"Fredimoses","affiliation":[],"nameIdentifiers":[]},{"name":"Zhou, Xuefeng","givenName":"Xuefeng","familyName":"Zhou","affiliation":[],"nameIdentifiers":[]},{"name":"Ai, Wen","givenName":"Wen","familyName":"Ai","affiliation":[],"nameIdentifiers":[]},{"name":"Tian, Xinpeng","givenName":"Xinpeng","familyName":"Tian","affiliation":[],"nameIdentifiers":[]},{"name":"Yang, Bin","givenName":"Bin","familyName":"Yang","affiliation":[],"nameIdentifiers":[]},{"name":"Lin, Xiuping","givenName":"Xiuping","familyName":"Lin","affiliation":[],"nameIdentifiers":[]},{"name":"Xian, Jia-Yun","givenName":"Jia-Yun","familyName":"Xian","affiliation":[],"nameIdentifiers":[]},{"name":"Liu, Yonghong","givenName":"Yonghong","familyName":"Liu","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus \u003ci\u003eAspergillus westerdijkiae\u003c/i\u003e SCSIO 05233"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Hematology"},{"subject":"Inorganic Chemistry"},{"subject":"FOS: Chemical sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences"},{"subject":"Sociology"},{"subject":"FOS: Sociology","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Pharmacology"},{"subject":"Microbiology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.2011808","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"A new methyl 2-(4-((2-hydroxy-3-methylbut-3-en-1-yl)oxy)phenyl) acetate \u003cb\u003e1\u003c/b\u003e, together with five known compounds \u003cb\u003e2\u003c/b\u003e–\u003cb\u003e6\u003c/b\u003e, was isolated from the culture of the deep sea-derived fungus \u003ci\u003eAspergillus westerdijkiae\u003c/i\u003e SCSIO 05233. The new structure was determined by NMR (\u003csup\u003e1\u003c/sup\u003eH and \u003csup\u003e13\u003c/sup\u003eC NMR, HSQC, HMBC and MS) and optical rotation analysis. Compound \u003cb\u003e5\u003c/b\u003e displayed weak inhibitory activities towards K562 and promyelocytic HL-60 with IC\u003csub\u003e50\u003c/sub\u003e values of 25.8 and 44.9 μM, and compound \u003cb\u003e6\u003c/b\u003e showed strong antifouling activity with EC\u003csub\u003e50\u003c/sub\u003e value 8.81 μg/mL.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/collections/Westerdijkin_A_a_new_hydroxyphenylacetic_acid_derivative_from_deep_sea_fungus_i_Aspergillus_westerdijkiae_i_SCSI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