{"data":{"id":"10.6084/m9.figshare.c.1978793","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.1978793","prefix":"10.6084","suffix":"m9.figshare.c.1978793","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Liu, Kai","givenName":"Kai","familyName":"Liu","affiliation":[],"nameIdentifiers":[]},{"name":"Zheng, Youkun","givenName":"Youkun","familyName":"Zheng","affiliation":[],"nameIdentifiers":[]},{"name":"Miao, Cuiping","givenName":"Cuiping","familyName":"Miao","affiliation":[],"nameIdentifiers":[]},{"name":"Xiong, Zijun","givenName":"Zijun","familyName":"Xiong","affiliation":[],"nameIdentifiers":[]},{"name":"Xu, Lihua","givenName":"Lihua","familyName":"Xu","affiliation":[],"nameIdentifiers":[]},{"name":"Guan, Huilin","givenName":"Huilin","familyName":"Guan","affiliation":[],"nameIdentifiers":[]},{"name":"Yang, Yabin","givenName":"Yabin","familyName":"Yang","affiliation":[],"nameIdentifiers":[]},{"name":"Zhao, Lixing","givenName":"Lixing","familyName":"Zhao","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"The antifungal metabolites obtained from the rhizospheric \u003ci\u003eAspergillus\u003c/i\u003e sp. YIM PH30001 against pathogenic fungi of \u003ci\u003ePanax notoginseng\u003c/i\u003e"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Plant Biology"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Infectious Diseases"},{"subject":"FOS: Health sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences"},{"subject":"Ecology"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biotechnology"},{"subject":"Pharmacology"},{"subject":"Microbiology"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"Eight anthraquinones (\u003cb\u003e1–8\u003c/b\u003e), three xanthones (\u003cb\u003e11–13\u003c/b\u003e) and two phenols (\u003cb\u003e9–10\u003c/b\u003e) were isolated from \u003ci\u003eAspergillus\u003c/i\u003e sp. associated with \u003ci\u003ePanax notoginseng\u003c/i\u003e, and their structures were determined as ziganein-1-methyl ether (\u003cb\u003e1\u003c/b\u003e), 8-\u003ci\u003eO\u003c/i\u003e-methylchrysophanol \u003cb\u003e(2\u003c/b\u003e), averythrin (\u003cb\u003e3\u003c/b\u003e), averufin (\u003cb\u003e4\u003c/b\u003e), 8-\u003ci\u003eO\u003c/i\u003e-methyl averufin (\u003cb\u003e5\u003c/b\u003e), versicolorin B (\u003cb\u003e6\u003c/b\u003e), averantin (\u003cb\u003e7\u003c/b\u003e), methyl-averantin (\u003cb\u003e8\u003c/b\u003e), arugosin C (\u003cb\u003e9\u003c/b\u003e), diorcinol (\u003cb\u003e10\u003c/b\u003e), sterigmatocystin (\u003cb\u003e11\u003c/b\u003e), demethylsterigmatocystin (\u003cb\u003e12\u003c/b\u003e) and dihydrosterigmatocystin (\u003cb\u003e13\u003c/b\u003e) by spectroscopic analyses. Compounds \u003cb\u003e1\u003c/b\u003e, \u003cb\u003e2\u003c/b\u003e and\u003cb\u003e 5\u003c/b\u003e were the novel isolates from genus \u003ci\u003eAspergillus\u003c/i\u003e. Compounds \u003cb\u003e3\u003c/b\u003e, \u003cb\u003e6\u003c/b\u003e and\u003cb\u003e 7\u003c/b\u003e exhibited antifungal activity against \u003ci\u003eFusarium\u003c/i\u003e\u003ci\u003esolani\u003c/i\u003e, pathogenic fungus of \u003ci\u003eP. notoginseng\u003c/i\u003e, with minimum inhibitory concentrations (MICs) of 16\u003cb\u003e–\u003c/b\u003e32 μg/mL, and compounds \u003cb\u003e1\u003c/b\u003e, \u003cb\u003e3\u003c/b\u003e, \u003cb\u003e4\u003c/b\u003e, \u003cb\u003e7\u003c/b\u003e and \u003cb\u003e9\u003c/b\u003e showed antibacterial activity against \u003ci\u003eBacillus\u003c/i\u003e\u003ci\u003esubtilis\u003c/i\u003e with MICs of 64–128 μg/mL, 16–32 μg/mL, 8–16 μg/mL, 16–32 μg/mL and 64–128 μg/mL, respectively. The metabolites showed the potential value in the research of antifungal agents, especially in searching for a biocontrol of diseases of \u003ci\u003eP. notoginseng\u003c/i\u003e. The preliminary structure–activity relationships have been discussed for some of the compounds.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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