{"data":{"id":"10.6084/m9.figshare.c.1965146.v1","type":"dois","attributes":{"doi":"10.6084/m9.figshare.c.1965146.v1","prefix":"10.6084","suffix":"m9.figshare.c.1965146.v1","identifiers":[],"alternateIdentifiers":[],"creators":[{"name":"Yang, Wei","givenName":"Wei","familyName":"Yang","affiliation":[],"nameIdentifiers":[]},{"name":"Cui, Yu-Ming","givenName":"Yu-Ming","familyName":"Cui","affiliation":[],"nameIdentifiers":[]},{"name":"Zou, Jing-Feng","givenName":"Jing-Feng","familyName":"Zou","affiliation":[],"nameIdentifiers":[]},{"name":"Wang, Cai-Yun","givenName":"Cai-Yun","familyName":"Wang","affiliation":[],"nameIdentifiers":[]},{"name":"Huang, Wei-Sheng","givenName":"Wei-Sheng","familyName":"Huang","affiliation":[],"nameIdentifiers":[]},{"name":"Zhang, Jin","givenName":"Jin","familyName":"Zhang","affiliation":[],"nameIdentifiers":[]},{"name":"Xu, Li-Wen","givenName":"Li-Wen","familyName":"Xu","affiliation":[],"nameIdentifiers":[]}],"titles":[{"title":"Investigation of the Mitsunobu Reaction of BINOL and Cinchona Alkaloids: Inversion or Retention of Configuration?"}],"publisher":"Taylor \u0026 Francis","container":{},"publicationYear":2015,"subjects":[{"subject":"Mathematics"},{"subject":"FOS: Mathematics","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Biological Sciences"},{"subject":"Chemistry"},{"subject":"Earth and Environmental Sciences"},{"subject":"Biotechnology"},{"subject":"Genetics"},{"subject":"FOS: Biological sciences","schemeUri":"http://www.oecd.org/science/inno/38235147.pdf","subjectScheme":"Fields of Science and Technology (FOS)"},{"subject":"Engineering"},{"subject":"Biochemistry"}],"contributors":[],"dates":[{"date":"2015-12-05","dateType":"Created"},{"date":"2019-08-19","dateType":"Updated"},{"date":"2015","dateType":"Issued"}],"language":null,"types":{"ris":"GEN","bibtex":"misc","citeproc":"article","schemaOrg":"Collection","resourceType":"Collection","resourceTypeGeneral":"Collection"},"relatedIdentifiers":[{"relationType":"IsIdenticalTo","relatedIdentifier":"10.6084/m9.figshare.c.1965146","relatedIdentifierType":"DOI"}],"relatedItems":[],"sizes":[],"formats":[],"version":null,"rightsList":[{"rights":"Creative Commons Attribution 4.0 International","rightsUri":"https://creativecommons.org/licenses/by/4.0/legalcode","schemeUri":"https://spdx.org/licenses/","rightsIdentifier":"cc-by-4.0","rightsIdentifierScheme":"SPDX"}],"descriptions":[{"description":"An efficient approach toward the construction of multistereogenic binaphthol (BINOL)–derived alkaloids with C\u003csub\u003e2\u003c/sub\u003e-axial and sp\u003csup\u003e3\u003c/sup\u003e central chirality has been accomplished. The reaction of BINOL and cinchona alkaloids was occurred smoothly under the Mitsunobu conditions, which led to the synthesis of a new family of complicated functional molecules based on chiral BINOL and cinchona alkaloids. In addition, on the basis of the experimental results, we provided a possible explanation for the intramolecular tertiary amine-induced retention of configuration at C9 of cinchona alkaloids while the inversion of configuration was observed with general alcohols under classic Mitsunobu conditions.","descriptionType":"Abstract"}],"geoLocations":[],"fundingReferences":[],"xml":"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","url":"https://tandf.figshare.com/collections/Investigation_of_the_Mitsunobu_Reaction_of_BINOL_and_Cinchona_Alkaloids_Inversion_or_Retention_of_Configuration_/1965146/1","contentUrl":null,"metadataVersion":2,"schemaVersion":"http://datacite.org/schema/kernel-4","source":"mds","isActive":true,"state":"findable","reason":null,"viewCount":0,"viewsOverTime":[],"downloadCount":0,"downloadsOverTime":[],"referenceCoun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